Best CBD Oil for Pain Relief & Inflammation in 2022
CBD oil is a well-known natural healing product for pain relief. Is it, however, truly effective? Learn what the research says, how to use CBD oil, and why so many people are switching from prescription pain relievers to CBD oil. Individuals all around the world suffer from chronic pain.
But, CBD oil and other cannabis extracts have demonstrated promising results in the management of pain in recent years, without the negative side effects associated with prescription medicines. CBD products are being used to treat arthritis, multiple sclerosis, migraine headaches, amyotrophic lateral sclerosis, fibromyalgia, nerve damage, PMS, and a variety of other ailments.
Chronic inflammation, spasms, tension, and anxiety can also be treated with such products. Finding the right CBD oil to help with your symptoms might be difficult. However, the market is filled with costly CBD oils that do not work and offer poor value to those who need them the most. But do not worry, as we have compiled a list of the best brands offering CBD oil for pain in this article.
Best CBD Oil Products For Joint Pain – 2022’s Buying Guide
: Overall Best CBD Oil On The Market, Editor’s Pick: Strongest & Most Potent CBD Oil For Pain Management CBD : Most Reliable CBD Tinctures For Chronic Pain & Inflammation: Full-Spectrum CBD Oil For Optimal Relief & Relaxation: Citrus Flavored Hemp Oil for Beginners
#1. Exhale Wellness: Overall Best CBD Oil On The Market, Editor’s Pick
Exhale is situated in Los Angeles and is committed to selling only the highest quality hemp goods on the market. It keeps producing effective CBD products in order to inspire people to live healthier, more relaxed lives.
Each bottle includes CBD derived from the natural hemp plant, as well as a delectable flavor and intriguing aromas. Pesticides, herbicides, and other chemical fertilizers are not used during the growing process. As a result, all of the products are organic, vegan, and natural.
Exhale Wellness offers CBD and delta-8 products in a variety of flavors and strains. Hawaiian Haze, Sour Space Kandy, OG Kush, Northern Lights, Skywalker OG, Cookies, Zkittles, Sour Diesel, and Gorilla Glue are just a few of the strains offered. As a result, it is reasonable to say that there is plenty to choose from, and these products can aid a wide range of conditions.
Exhale Wellness additionally offers excellent after-sales service. You can place an order without cost worries since all items are placed with free shipping and every product is covered by a 30-day money-back guarantee.
Exhale Wellness has a partnership with Colorado farms from which it obtains all of its top-quality hemp. The hemp is grown under strict standards, ensuring the products’ purity and safety. The CO2 method of extraction is used to make CBD oil from superior extracts. The CBD oil has no additives, artificial colors, flavorings, or preservatives. As a result, we can guarantee its safety.
The oil is available in two potencies — 600mg and 1,200mg — and it comes in a compact 30ml dropper bottle. Although there is not much information about Exhale Wellness’ CBD oil in the product description area, it is very well known that it is one of the company’s most potent products. Once you have tried it, you will understand what we are talking about.
CBD oil begins to work pretty quickly and helps in pain management. It gives you a relaxed feeling without making you tired, and it assists you in remaining more concentrated while performing your regular tasks. You can also save an additional 25% by subscribing to the service.
- Quality-centric brand
- Full-spectrum CBD oil
- 100% organic
- 30-day money-back guarantee
- Free shipping
- Third-party lab tested
- Only available online
Exhale Wellness’ CBD oil is one of the brand’s best-selling items. The reviews we read about the oil were largely positive, and customers say the oil is quite effective. The superior grade of CBD oil is immediately apparent after ingestion. It has helped a number of clients stay focused while also relieving discomfort. Customers have strongly recommended this CBD oil, which is reasonably priced and is stated to be preferable over many others.
#2. BudPop: Strongest & Most Potent CBD Oil For Pain Management
BudPop was founded by a group of people who were passionate about the benefits of potent CBD oil and believed that CBD should be accessible to everyone who needs it at a reasonable cost. They wanted to accomplish something meaningful with their time that would benefit others by enhancing their quality of life. It gives them comfort to know that they can contribute to something so significant.
BudPop offers true seed-to-sale purchasing to its consumers, and their industrial hemp is cultivated and extracted in strict conformity with regulations. To assure consistency and quality, every product that leaves the facility must be third-party lab tested.
BudPop is proud to work with the Hemp Pilot Research Program to supply high-quality CBD extract to customers in all 50 U.S. states. Despite the fact that hemp cultivation, extraction, and manufacturing are still relatively new in the United States, their team of experts and partners has dedicated their lives to industrial farming methodologies, food-grade compound extraction, vegetable genetics, and quality control, to name a few.
The BudPop CBD Oil Tincture is a good place to start because they allow for customized doses. The measure marks on the dropper dispenser, which are marked with 0.25, 0.50, 0.75, and 1mL, allow for accuracy and flexibility in portion sizes.
This is a high-quality, completely compliant CBD product derived from industrial hemp produced in the United States. Each plant is cultivated organically, tested by a third-party lab, and guaranteed to be contaminant-free.
Moreover, BudPop uses a CO2 extraction procedure to extract CBD from plant material while filtering away unnatural compounds, resulting in a high concentration of pure CBD oil. The process of extraction is crucial for obtaining the best-grade cannabidiol from the hemp plant.
- Two flavors to choose from — Peppermint and Natural
- CO2 extraction procedure used
- Third-party lab tested
- Free shipping
- 30-day money-back guarantee
- Only available on BudPop’s official website
Customers are generally satisfied with the CBD oils that this brand offers, and they like the flavors that are offered. They say the oils are very effective and have good potency, and they would recommend this brand to others.
#3. Hollyweed CBD: Most Reliable CBD Tinctures For Chronic Pain & Inflammation
The Hollyweed team always cares for the well-being of people and consists of individuals who have worked in the medicinal cannabis industry for decades. They are dedicated to developing goods that help them achieve their health goals, and they believe in the healing properties of hemp.
They saw a lack of consistency and transparency in the CBD industry when they first started their business, so they decided to focus on high-quality, dependable products. With such a dedicated brand, you can be assured you will only receive the highest quality items.
When it comes to supplying the highest quality CBD products, you can count on and trust this brand. If you prefer to inhale your CBD, try their vape cartridges, which come in a range of strains.
Hemp seed oil, which is included in Hollyweed’s CBD oil, is a nutrient-dense superfood that can help you maintain a balanced diet. This incredible, natural superfood is high in Omega 3, 6, and 9 vital fatty acids, and it provides a full protein supply for vegans. Hemp seed oil has a rich, earthy flavor that might help you take charge of your body’s health.
CBD oil, also known as cannabidiol, is a naturally occurring substance found in hemp that is non-psychoactive. The endocannabinoid system (ECS) in the body is supported by this remarkable cannabinoid, and our body’s sleep, emotions, digestion, hunger, and metabolism are all aided by the ECS.
Furthermore, Hollyweed makes sure their customers receive only the best quality products, which is why this CBD oil is third-party lab tested to check its accurate potency.
Hollyweed’s CBD oil comes in a practical glass dropper vial, and you can take one or more servings twice a day or as needed by dropping it directly in the mouth or by including it in meals. It comes in strengths of 300mg, 600mg, 1,200mg and 3,000mg, so there is something for every user, whether you are a newbie or an experienced CBD oil user.
- Naturally-grown hemp
- Third-party laboratory tested
- 30-day money-back guarantee
- CO2 extraction method used
- Free shipping within the U.S.
- Can only be purchased online
According to online reviews, customers are mostly pleased with this product. A variety of users, both new and experienced, were happy with the strength and potencies of this CBD oil. Overall, they consider Hollyweed to be a reliable brand, and they plan to buy from them again. This oil, they allege, has provided them with physical and mental relief.
#4. Cheef Botanicals: Full-Spectrum CBD Oil For Optimal Relief & Relaxation
Cheef Botanicals is a well-known organic product firm with over 25 years of experience. We admire this company’s commitment for providing education about natural options, along with the risks and side effects of pharmaceutical therapies.
Cheef Botanicals has a line of organic CBD products made from plants. The products are manufactured using cruelty-free, organic, vegan ingredients that are also non-GMO, gluten-free, and dairy-free. They exclusively use natural ingredients and avoid artificial colors and tastes.
The product lines go through extensive research, development, and refining to create their unique, one-of-a-kind, vegan CBD goods. They are ensuring their consumers obtain the best and purest CBD products by doing so.
Cheef’s 300mg full-spectrum CBD oil is a wonderful place to start if you are new to cannabidiol. To promote a more pure consumption experience, this mild oil exclusively contains CBD and hemp seed oil. These oils embrace full-plant components including subsidiary cannabinoids and terpenes by employing full-spectrum hemp extract. This contributes to a richer, greater objective.
With only 300mg of CBD, if this oil is used by anyone with a CBD tolerance, we recommend trying higher doses, which are available up to 3,000mg per bottle, so it is potent enough. However, for those of you who are CBD rookies, this oil can be a fantastic option. Just keep in mind that you might get a hint of hemp’s earthy flavor.
- Free shipping
- All-natural ingredients
- Third-party lab tested
- 30-day money-back guarantee
- Full-spectrum CBD
- International shipping not available
We discovered the majority of consumers are pleased with Cheef Botanicals’ CBD oil after reading the reviews. Customers who have purchased this brand in the past say they have never been dissatisfied. This CBD oil is the best place to start if you are new to the cannabidiol world. The dose is fairly low, but in those who require it, it will provide gentle, supporting benefits.
#5. FAB CBD: Citrus Flavored Hemp Oil for Beginners
FAB CBD is a resurrected brand that debuted in 2017 and has since worked out a way to capture customers’ interest with its diverse product offering. They are regarded as one of the greatest CBD product manufacturers in the business.
They sell items made entirely of natural materials obtained from hemp produced organically in Colorado. The goods are pesticide-free, gluten-free, and non-GMO, and they are also suitable for vegans.
CBD has swept the world in recent years, and while CBD tinctures offer benefits, they are also handy and inconspicuous to use. With its significant analgesic, anti-inflammatory, and muscle relaxant qualities, FAB CBD’s oils can help relieve pain. Allow the CBD oil to perform its magic in assisting you in a quicker recovery.
FAB CBD has a good reputation and is open and honest about its services and products. It offers a wide range of full-spectrum and isolated nutrients. Each product’s dosage is clearly labeled, and the website includes instructions on how to utilize everything. So, customers may easily predict what to expect from their items with this knowledge.
FAB CBD has tens of thousands of clients and has been listed in various publications’ “best CBD oil for pain” lists. As a result, it must be doing something correctly. FAB CBD passed the authenticity test first and foremost. The firm openly displays proof that its oil contains less THC and a substantial amount of CBD in their ‘Lab Report’ section.
For the record, ProVerde Laboratories performs the testing, and the CBD content of the 1,200mg natural oil drops is 36.28 mg per ml. The drops have a THC concentration of 0.22%, which is significantly below the regulatory limit.
The FAB CBD product range is 100% naturally and organically grown in Colorado, and it is GMO-free.
Citrus, Mint, Berry, Vanilla, and Natural are the five flavors available in FAB CBD oil drops. There are also four different strengths available, which are 300mg, 600mg, 1,200mg, and 2,400mg. So, regardless of if you are a beginner or an experienced user, you can find the product with the right potency and flavor that suits your needs the most.
Larger bottles, as is common, provide significantly better return on investment. It is worth noting that FAB’s costs have been drastically cut. In such a competitive industry, it must maintain acceptable expenses.
- Natural ingredients
- Third-party lab tested
- Provides efficient pain relief
- 30-day money-back guarantee
- Proper servings
- International shipping times can be lengthy
Customers share their great experiences in the reviews we read, and they were thrilled to discover that taking CBD oil made them feel more at ease.
Some of them chose to take a dose an hour before bedtime, and the quality of their sleep improved as a result. Even more importantly, some of them began to feel rejuvenated when they awoke, which they described as a completely new sensation for them.
What to Consider When Buying CBD Oil
Where to Buy CBD Oils
Now that you are familiar with what CBD is, your next issue might be where to get CBD oil. CBD oil can be found in a variety of places, including online, dispensaries, and specialty stores.
One disadvantage of purchasing CBD oil from a dispensary or specialized retail store is the lack of quality control. Because they buy items from outside extractors, retailers frequently do not provide lab results or purity analyses. When you buy CBD oil directly from brands that provide information about their manufacturing process as well as confirmed lab tests, you can be assured you are obtaining the highest-quality CBD oil available.
The Right Amount
Reputable CBD companies use hemp grown in the United States, use safe manufacturing methods, and subject their products to third-party lab tests. But, how long does CBD oil take to work, and are you getting the right amount? Now it is just time to consider another crucial question — how much CBD are you actually getting?
The amount on the front of most CBD oil bottles will range from 300mg to 10,000mg. This is the overall amount of CBD contained in the oil, not the amount of CBD oil included in each serving. The total CBD number on the front should be calculated by dividing the number of servings in the container to get the actual amount of CBD you will get.
We typically think that a higher-priced product is of higher quality in sales. But, this may not be the same when CBD oil is in question, as quality and price do not necessarily go hand in hand.
The Food and Drug Administration (FDA) discovered severe labeling errors in over 20 CBD-containing products in 2016. The items included much higher or lower quantities of CBD than claimed, according to an investigation, and some did not have any CBD at all.
When you decide which CBD oil to buy, do not just go for the most costly product on the market in the hopes of receiving the best. Instead, read about the company’s manufacturing process and look at their lab reports, or Certificates of Analysis (COAs), to see what you will get in each product batch.
Hemp was declared banned under the Controlled Substances Act of 1970, and the plant was also classified as a Schedule I substance, along with heroin, LSD, and ecstasy. As a consequence, international hemp became necessary, where growing regulations are less stringent than those set by the U.S. Department of Agriculture.
Therefore, for high-quality CBD oil, locally cultivated hemp is the best alternative. Plants grown on American farms are subjected to stricter quality controls, such as reduced pesticide exposure and improved growth quality. When looking for and purchasing high-quality CBD oil, make sure it originates from hemp plants farmed in the United States.
Risks and Side Effects
CBD is a naturally occurring substance, and as such, people who consume CBD alone face little danger if they are not using any other medications. CBD may engage in a variety of other medications, potentially increasing negative effects. Before using CBD, anyone who routinely takes prescription or over-the-counter drugs should consult their doctor.
While taking CBD, some people may have moderate side effects such as drowsiness and stomach distress. Because scientists are unsure whether CBD is safe to use during pregnancy, those who are pregnant should avoid it.
Many companies may add other ingredients to their CBD products to make them work better. Make sure a product does not include any other ingredients before buying it. Chemicals, flavoring additives, and other substances may not be appropriate for everyone.
Some ingredients may cause adverse reactions in some people. So, keep an eye out for other food sensitivities and look up any unusual ingredient names before purchasing any CBD product.
Another important factor to consider is the CBD product’s potency, which varies greatly depending on the needs of the individual. CBD dosages are typically expressed in milligrams. However, it is important to keep in mind that there is not a lot of human evidence to recommend optimum amounts for specific conditions.
It is best to start with tiny doses and work your way up until you have found the smallest effective dose with the fewest side effects. When one person has discovered the dosage that is most effective for them, they should stick to it. A person’s dose is determined by their metabolism, tolerance levels, and mode of delivery.
CBD Oils & Drops: Frequently Asked Questions
Q1. What is the difference between CBD oil and CBD drops?
CBD oil is the umbrella term for hemp-derived CBD included in an orally ingestible oil. A CBD tincture is a type of product that is a liquid that may be consumed by mouth.
These names are frequently used interchangeably while shopping; however, they are usually hemp-based cannabidiol products with a carrier oil like MCT oil. Looking at the back label of the bottle is the easiest approach to figure out what components are used.
Q2. How do I use CBD drops?
Remove the top and then use the dropper to select the quantity you would like to consume. Many people who are new to CBD start with a smaller dose as they become used to incorporating the natural element into their daily routine.
Once you have decided on the amount you want, place it under your tongue, where the mucous membranes will absorb it. The majority of CBD oil users choose to take it in the morning and at night, but your schedule will be determined by your actual goals like enhancing testosterone levels .
Q3. How long does it take for CBD oil to work?
It varies on how much you consume, your body type, and how you metabolize; however, a sublingual substance like a tincture will usually give you a result in just a few minutes. It is a rapid and efficient approach to consume plant-based cannabis oils because the substance is absorbed by the mucous membranes under the tongue.
Q4. Is CBD a legal substance?
CBD products derived from hemp that contain less than 0.3% THC are allowed in the United States, but they are still banned in several states. CBD products produced from marijuana, however, are banned on the federal level but are legal in some states. So, check your local laws, especially if you are traveling.
Q5. What is a Certificate of Analysis (COA)?
A Certificate of Analysis, or COA, is one of the most important factors to consider when purchasing CBD. It is simply a form of quality control that verifies the product contains the levels of CBD claimed or advertised by the brand. A COA should be obtained from a third-party source rather than the maker or brand in order to provide reliable and unbiased results. A COA from a third-party is usually separated into various sections.
One portion will usually list the amount of CBD, THC, and other, less plentiful cannabinoids in the product, such as CBN or CBC. The potency of a product is determined by these readings. Another segment will look at possible pollutants in the product, such as pesticides or bacteria. A separate section will detail any heavy metal or chemical pollution, such as residual solvents.
A COA should be posted on the website of a CBD company so potential purchasers can inspect a product prior to buying it. It is also crucial that the COA originates from a reputable lab. If at all possible, look for labs that have been accredited by the International Organization for Standardization (ISO).
Q6. What is CBD’s mechanism of action?
To begin, it is crucial to understand that we all have a system within our bodies that regulates our immune systems’ reaction, our sleep patterns, our moods, and how we perceive pain. The endocannabinoid system (ECS) is responsible for dealing with the cannabinoids produced naturally by our bodies. CB1 receptors (found in the brain and neurological system) and CB2 receptors (found throughout the body) are two types of cannabinoid receptors that do this.
While THC binds to endocannabinoid receptors in the brain and causes a high, CBD does not. Instead, it encourages your body to make better use of its own natural supply of cannabinoids. That is, it can affect the amount of pain you feel in your brain by inhibiting or activating molecules in the ECS.
Q7. Can CBD be used to alleviate general body aches and pains?
CBD’s cannabinoids bind to certain receptors in the activation of the immune response after being eaten. The CB2 receptor, for example, aids in the management of pain in the immune system. When the purpose of using CBD oil is for pain, it changes the way the brain and body react to the signals it receives, resulting in a reduction in pain.
CBD may also assist in relieving the pain of joint injuries acquired when exercising, as well as headaches and muscular soreness. It is crucial to keep in mind that CBD products are not intended to identify, treat, cure, or prevent any condition.
Q8. What is the “entourage effect,” and how does it work?
The entourage effect occurs when a number of components from the industrial hemp plant operate together. These ingredients work together to maximize the plant’s potential benefits, with each molecule enhancing the medical properties of the others while lowering the chance of side effects. This synergistic interaction is expected to increase the potential for therapeutic success, but clinical studies have yet to confirm the impact of this effect.
Q9. What is the significance of full-spectrum?
CBD is one of over 100 cannabinoids found in the cannabis plant. Full-spectrum CBD oil contains all of the cannabinoids found in the cannabis plant, but just tiny quantities of THC.
These cannabinoids work in tandem with CBD to give your body benefits that CBD isolation cannot. The “entourage effect” describes how cannabinoids and terpenes work better together in groups.
Conclusion: Does CBD Oils & Tinctures Really Help With Pain Management?
You should now be ready to make an informed decision after reading the reviews and recommendations provided in this article. All of the brands are effective in relieving pain, have a great taste, and are reasonably priced for the quantity and quality of the products.
If we had to make our pick, Exhale Wellness and BudPop offer the best CBD oils for pain, in our opinion. On the other hand, all of the other brands are equally good and offer their own set of benefits. CBD oils may be the answer for anyone who is suffering from pain.
We are certain you will make the best choice for you and your body since you are the one who understands what is best for you. Before taking CBD oils or any other cannabis products, see your doctor if you are pregnant, have a medical condition, or are on any medication.
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Best CBD Oil for Pain Relief & Inflammation: Highest Quality Brands On The Market
Over the past three years, CBD oil has become increasingly popular as a health and wellness supplement.
One of the main reasons people are interested in trying CBD oil is because of its pain-killing benefits. We’ll get into the details of how CBD is suggested to help with pain later, along with some suggestions for the best CBD oils for pain and inflammation.
The ability for CBD to help with pain is a significant advantage over conventional pain management options — which often involve addictive and potentially harmful medications. Instead, this natural supplement has very few side effects and an exceptional safety profile — all without compromising on effectiveness.
But how do you choose the right CBD oil for the job?
This is an important question to ask because the truth of the matter is that not all CBD oils work. Many simply contain too little CBD to be of any help, while others contain harmful contaminants like heavy metals, pesticides, or chemical solvents — all of which could add to the pain you’re already experiencing by damaging the sensitive nerve cells around the body.
We’re going to cover all of this in the article below. You’ll learn how to spot a high-quality CBD oil and how current evidence shows CBD to work inside the body.
This is a big topic, so let’s get started with our list of top-rated CBD oils for pain.
Top 10 Best CBD Oil Brands for Pain Management in 2022
Not sure which CBD oil to buy to help with chronic pain? Before we get into the nitty-gritty of how CBD is suggested to work for pain and inflammation, here’s our top 5 list of CBD oils I’ve used myself for back pain.
We’ll also offer some advice on a few ways you can spot a trustworthy CBD vendor even if they didn’t quite make it onto our list.
I’ve been using CBD for over 5 years now and I’ve stumbled upon some stellar companies with top-notch oils and fly-by-night businesses with oils that can’t simply don’t work.
I have a relatively short list of CBD brands that I fully trust and I want to share my choices with you so you can avoid some of the headaches and disappointment I’ve already endured.
Here are my top 10 CBD oil brands for pain:
1. Royal CBD (Best CBD Oil On The Market)
|Total CBD Content||250 – 2500 mg|
|Available Flavors||Natural, Mint, Vanilla, Berry|
|Potency||8.3 – 83.3 mg/mL|
Get 15% off all Royal CBD products. Use code “CFAH” at checkout.
Why Royal CBD is My Top Pick:
As skeptical as I am towards the majority of new CBD brands, I decided to give Royal CBD a try because I liked the company’s dedication to quality. I love seeing companies that take what they do seriously.
You can tell right away from the color, flavor, and consistency of the oil that you’re dealing with a product well above average.
This oil is cheaper than most of the other premium CBD oils I’ve tried, comes in a full range of potencies, and uses some of the best full-spectrum hemp extracts I’ve ever seen. I’ve heard friends using this brand for quite some time and decided to give it a try for myself — so I ordered a few bottles in different strengths.
After taking the Royal CBD’s 2500mg full-spectrum CBD oil for just over a week, I noticed an improvement in my back pain. There was a time when I had serious problems falling asleep because of the sharp pains in my back that seemed to intensify whenever I laid down to fall asleep. It was a nightmare. I’d lay awake for hours changing positions to try and find a spot that didn’t leave me writhing in discomfort.
With this oil, my experience went far beyond what I expected. Not only did it help ease the pain, but my overall quality of sleep improved. I mean, I didn’t sleep longer but I began to wake up rested and with a clear head.
My favorite combination for this particular oil is the vanilla in the 1000 mg bottle. This is the largest potency option currently offered by Royal CBD and has the best value overall. I took the oil twice per day, once in the morning when I woke up, and again in the evening before bed. One bottle of the 1000 mg CBD oil lasted me about a month.
- Sourced from US-grown organic hemp
- Extracted with supercritical CO2
- Contains the full spectrum of cannabinoids and terpenes
- Available in 4 different strengths
- Up to 2500mg of CBD per bottle
- Lab-tested for potency and purity
- Great natural flavors (no aftertaste and comes in multiple flavor options)
- Free shipping within the USA
- Newer brand on the market that only sells online, no physical presence
2. Gold Bee (Best Organic CBD Oil)
- Premium Colorado-grown hemp
- CO2 extraction
- Contains full-spectrum CBD
- Delicious kiwi flavor
- Sweetened with organic honey
- Lab-tested for potency and purity
- Only one flavored option available
- No high-strength oils (yet)
What I Like About Gold Bee:
I honestly believe Gold Bee makes the best organic CBD products out there. The brand combines premium Colorado-grown hemp with organic honey sourced from the Brazillian Rainforest. While Gold Bee offers a modest selection of oils — with up to 1200 mg of CBD per bottle — the formula is spot-on when it comes to the quality of ingredients. I’m totally not going to complain about the potency, as my back pain and sleep quality got better than with some high-strength oils I’ve tried in the past. Considering the quality of these products, they actually come at a bargain price. If you want to try other formats from Gold Bee, you can choose between its high-strength capsules and CBD-infused honey.
3. CBDPure (Runner Up)
|Total CBD Content||100 – 600 mg|
|Potency||1.6 – 10 mg/mL|
What I Like About CBDPure CBD Oil:
I love how transparent this company is. If I were judging companies solely by their transparency level, CBDPure would have scored the second place, right after Royal CBD. The company provides all the details about each stage of production when making this CBD oil. You can find all the third-party lab test results for each batch on the product page — something we’ve come to expect from any high-quality CBD company.
What really makes this company stand out is its incredible satisfaction guarantee. If you order the product and decide it wasn’t working for you, simply send it back and get a full refund. This satisfaction guarantee extends over 3 whole months — which is about three times longer than the industry average.
I keep a bottle or two of CBDPure oil in my medicine cabinet for achy moments after a run or hike with the kids.
The only real downside to this oil is the potency — which comes in denominations of 1.5, 5, and 10 mg/mL. This is suitable for more minor symptoms, but may not be enough for people with heavy CBD demands.
- Sourced from Colorado-grown organic hemp
- Extracted with supercritical CO2
- Tested for the cannabinoid content and purity in a third-party lab
- Rock-solid 90-day return policy
- Narrow product range
- Low potency
- They don’t ship to every state (i.e. Louisiana, Indiana, Arkansas, Kansas)
|Total CBD Content||300 – 4000 mg|
|Available Flavors||Unflavored, Acai Berry, Orange Creamsicle, Peppermint, Watermelon|
|Potency||10 – 133.3 mg/mL|
What I Like About HempBombs:
I used HempBombs CBD isolate-based hemp oil for quite some time before switching to full-spectrum CBD oil and in my opinion, this is the best brand when it comes to CBD isolates. Their products contain 99% pure CBD and ZERO THC.
Now don’t get me wrong, CBD isolates are great, they offer consistent doses of CBD, contain 0% THC, and are generally cheaper than their full-spectrum counterparts. In most cases, I like using a full-spectrum extract like Royal CBD oil because of something called the entourage effect — which is a concept highlighting the phenomenon where cannabinoids like CBD tend to work better when other hemp-derived compounds are also present.
In isolates, the only cannabinoid present is CBD.
HempBombs CBD oil is available in five different strengths — from 300mg to 4000mg per bottle. The CBD is added in the form of a 99% pure isolate — which means there’s going to be virtually no traceable amounts of any other cannabinoids, including THC, CBC, CBG, or CBN.
You can also buy these oils in different flavors. Hemp Bombs often adds new flavors to the list, but my all-time personal favorite is the Acai berry. It’s not too sweet but adds a really pleasant flavor to the otherwise bland CBD and MCT oil formula.
- Sourced from 100% certified organic hemp from European farms
- Extracted with supercritical CO2
- Completely THC-free
- Tested in third-party laboratories for purity and potency
- Available in 5 separate strengths
- Up to 4000mg of CBD per bottle
- Lacks the synergistic effects from other cannabinoids
- The highest potencies are overkill for most users
- Uses synthetic flavoring agents
|Total CBD Content||250 – 5000 mg|
|Potency||8.3 – 166 mg/mL|
What I Like About CBDistillery:
CBDistillery is now one of the largest CBD companies in North America. The company began in 2016 as a legacy brand for Balanced Health Botanicals.
Over the years, CBDistillery has had the chance to really dial-in its CBD oil formula. The company now sells its CBD oil in two formats — “full-spectrum” and “THC-free.” The THC-free option is great for people who want to benefit from the synergy of CBD and other cannabinoids but without bringing any THC whatsoever into their system.
Even the full-spectrum option contains less than 0.3% THC — which is well below the amount needed to cause any psychoactive effects. These oils are both completely non-psychoactive.
You can choose between five different strengths, starting at 250mg up to 5000mg of CBD per bottle. This covers just about every range of potencies you would ever need. We recommend opting for the higher potency options because they have the best value overall. The higher potency you purchase, the further your dollar gets you.
The more potent options also las the longest because you need smaller amounts of the oil each time to get the desired dose of CBD.
I tried the 1000mg bottle to keep myself calm during the first few months after giving birth to my first son and I must admit it helped me maintain my sanity during that time. I found it to have a remarkable calming effect on the body and mind.
- Available as full-spectrum CBD or pure CBD oil (THC-free)
- 5 strengths to choose from
- Carries up to 33.3 mg of CBD per mL (in the 1000 mg bottle)
- Excellent value CBD oil
- The hemp isn’t certified organic
- No flavor options available
- The company website is clunky and hard to navigate
6. NuLeaf Naturals
|Total CBD Content||240 – 4850 mg|
What I Like About NuLeaf Naturals
Nuleaf Naturals is one of the most popular CBD companies in the United States — most likely related to how long the company has been in the business of selling CBD. Nuleaf naturals were one of the first CBD companies to enter the mainstream market.
Despite the companies longstanding reputation, Nuleaf Naturals only sells one CBD oil. When you go to the website you’ll find a few different options, including a pet oil — but it’s important to understand that these are all the exact same full-spectrum extract, the only difference is the bottle sizes.
We love the simplicity of Nuleaf Naturals product lineup. The oils come with a decent potency of around 48 mg/mL, and just about every bottle size you can imagine. This makes it easy for everybody to find a product that works for them regardless of the budget.
With that said, if you have the cash, we highly recommend getting the larger bottle sizes in order to get the best value for your money.
You can choose between five different sizes:
- Sourced from organic Colorado-grown hemp
- Extracted using supercritical CO2
- Made from a full-spectrum hemp extract
- More expensive than the other brands in this ranking
- Narrow product range
7. Charlotte’s Web
|Total CBD Content||200 – 1800 mg|
|Available Flavors||Mint Chocolate, Lemon Twist, Orange Blossom, Olive Oil|
|Potency||7 – 60 mg/mL|
About Charlotte’s Web:
Charlotte’s Web is one of the pioneers in the American CBD industry. Established by the Stanley Brothers, the company has coined a reputation of a trustworthy manufacturer by helping now late Charlotte Figi with her treatment-resistant epilepsy. Although the company has recently received a warning letter from the FDA due to their health claims, they still have many faithful customers and a massive number of positive reviews on the web.
Charlotte’s Web CBD oil comes in several potencies: 200 mg, 500 mg, 1500 mg, and 1800 mg of CBD per bottle. The highest strength offers 60 mg of full-spectrum CBD per milliliter. There are two bottle sizes to choose from: 30 mL and 100 mL; Charlotte’s Web also has flavored variants of its CBD oil, including Lemon Twist, Orange Blossom, Mint Chocolate, and Olive Oil.
What could the company do better?
First off, they could change their extraction method because they use ethanol, which is less efficient than CO2 extraction. Secondly, and most importantly, the suspension in olive oil makes them taste a bit bitter — even in the flavored versions.
- One of the most reputable brands on the market
- Full-spectrum CBD
- Delicious flavored versions
- Up to 1800 mg of CBD per bottle
- Available in two sizes: 30 mL and 100 mL
- Third-party tested for potency and purity
- Non-organic hemp
- Ethanol extraction
- Suspension in olive oil (bitter taste)
- The company received a warning letter from the FDA in the past due to inappropriate health claims
|Total CBD Content||300 – 7500 mg|
|Available Flavors||Natural, Berry, Orange, Mint|
|Potency||10 – 250 mg/mL|
cbdMD is another popular manufacturer that offers a wide range of CBD extracts, from tinctures to gummies to capsules, bath bombs, topicals, sleep aids, and pet products.
The brand offers a wide range of pure CBD oils, with up to 7500 mg of CBD per bottle. The highest potency comes with a whopping dose of 200 mg of pure CBD suspended in MCT oil for higher bioavailability and a smoother flavor. cbdMD also has three flavored CBD oils: Berry, Orange, and Mint.
Despite an impressive potency range, cbdMD uses broad-spectrum CBD in their products, which doesn’t evoke the full entourage effect. The higher potency may not necessarily mean better results in this case.
The company has high transparency standards; not only does cbdMD broadly describe their activity from farming to testing, but they also provide batch-specific certificates of analysis for their products, including the results for potency and common contaminants like pesticides, heavy metals, and residual solvents.
- US-grown, non-GMO hemp
- CO2 extraction
- Up to 7500 mg of CBD per bottle
- Batch-specific certificates of analysis
- Limited entourage effect due to the lack of THC
- Most people don’t need such high doses of CBD in their routine
|Total CBD Content||500 – 3000 mg|
|Available Flavors||Natural, Citrus, Mint Chocolate|
|Potency||16 – 100 mg/mL|
Medterra is a small craft company from California. The brand offers premium CBD oils in different spectra: full-spectrum CBD, broad-spectrum CBD, and isolates. The potency of these products ranges between 500 mg and 3000 mg of CBD per bottle, which is a standard range. On top of the unflavored version, there are two flavored options: Citrus and Chocolate
Medterra prides itself on making the real full-spectrum CBD because each bottle of its full-spectrum CBD oil comes with 2 mg of THC. However, these products are only legal in the states that have legalized higher amounts of THC for recreational use. So, if you want to buy the company’s products in all 50 states, your options are limited to broad-spectrum CBD and CBD isolate. These provide more CBD per bottle — upwards of 1000 mg.
The entire Medterra’s product range is tested in a third-party laboratory for their CBD content and safety.
- Premium-grade CBD oils
- Up to 3000 mg of CBD per bottle
- Available as full-spectrum CBD, broad-spectrum CBD, and isolates
- Lab tested for potency and purity
- The “real” full-spectrum CBD oil isn’t available in all states
- Some of the lab reports indicate higher CBD levels than stated on the bottle
- No discounts for returning customers
10. Joy Organics
|Total CBD Content||450 – 900 mg|
|Available Flavors||Tranquil Mint, Fresh Lime, Summer Lemon|
|Potency||15 – 30 mg/mL|
About Joy Organics:
Joy Organics holds the reputation of one of the most reputable CBD vendors in the industry. The company was established by a woman named Joy Smith, who has been using CBD oil to manage her problems with pain and sleep. After experiencing the benefits of CBD first-hand, she has decided to share her passion for cannabis with other health-conscious consumers.
The brand sells a range of broad-spectrum CBD products from certified organic hemp. They have many positive reviews all over the Internet; they also haven’t received any warning letter regarding health claims from the FDA — unlike many companies in this space (even the veterans like Charlotte’s Web).
The Joy Organics CBD oil features a broad-spectrum CBD formula in a modest potency range, from 450 to 900 mg of CBD per bottle. You can choose from three refreshing flavors: Summer Lemon, Fresh Lime, and Tranquil Mint. The strongest version of the Joy Organics CBD oil contains 30 mg of broad-spectrum CBD in every milliliter, which is a standard dose for most people who take CBD oil for daily supplementation.
In 2018, one of the company’s flavored CBD oils was found to contain a fungicide that is commonly sprayed on citrus fruit during independent lab testing. Fortunately, Joy Organics recalled the product shortly after this incident and implemented a new third-party testing system to make sure there are no flaws in the end product.
- Non-GMO, US-grown hemp
- Supercritical CO2 extraction
- Broad-spectrum CBD
- Delicious flavors
- A bit expensive
- No high-strength oils
CBD Oil for Pain Management: Complete Guide for Beginners
Now that we’ve covered a few CBD oil options that are going to provide the best value for your money, let’s discuss how CBD is suggested to support chronic pain in the first place. We’ll also cover some of the most common ways people are using CBD oil for pain.
What is CBD Oil?
CBD stands for cannabidiol _ it’s one of the primary active ingredients in the cannabis plant. It’s completely non-psychoactive and offers a wide range of benefits to the human body.
CBD oil is a combination of a CBD extract, with a carrier oil to help dissolve and store the CBD. Most CBD oils use carrier oils like MCT oil, or hemp seed oil — which is then combined with CBD isolate, or full-spectrum hemp extract rich in CBD and other similar cannabinoids.
Cannabinoids like CBD are fat-soluble — which means they dissolve when mixed with oil, but won’t dissolve in water. By dissolving these compounds in an oil solution, the CBD becomes much easier to store and use. Instead of measuring out micrograms of CBD crystals or hemp resin, all you need to do is measure oil to get your dose of CBD. This can be done using a simple dropper that comes standard with most CBD oils.
Because of their ease of use, and long shelf-life, CBD oils have become the go-to method of using CBD and other hemp extracts.
You can also opt-out to use CBD-infused gummies if you wanted something discreetly, read our in-depth review on CBD Gummies to understand better.
How Does CBD Work?
Cannabis has been used for managing pain and inflammation for thousands of years.
The earliest records of the medical use of the herb date back to ancient China when the emperor Shen-Nung placed it among other therapeutic substances in the Chinese pharmacopeia (1). The leaves were wrapped around an injury as a poultice to reduce pain and discomfort, and reverse swelling and bruising.
Despite being a known medicine for a long time, scientists have only recently begun to unlock the mechanisms cannabis uses to achieve its important pain-killing benefits.
Since the discovery of the endocannabinoid system in 1992, CBD and other phytocannabinoids have been in the spotlight of modern medicine.
The endocannabinoid system is one of the most important neurochemical networks in the human body (2). It works by interacting with the endocannabinoid system — a series of hormones and receptors that help regulate over a dozen core processes in the human body. The active compounds in the cannabis plant are very similar to the naturally-produced hormones involved with our endocannabinoid system.
By interacting with the endocannabinoid system, CBD and other cannabinoids are able to modulate several key processes, such as:
- Immune function
- Sensory perception (including pain)
- Reproductive health
- Nerve function
How Can CBD Reduce Pain Transmission?
How does all of this relate to pain? The answer lies in the way pain is transmitted to the brain.
When we injure ourselves, cells in the immediate vicinity begin releasing compounds that trigger a cascade of inflammation and sensory activation — which is what triggers the pain transmission.
The pain signal is then sent to the spinal cord through a network of nerves distributed all around the body.
Once in the spine, the pain signal is sent through a gateway (opioid and vanilloid receptors) designed to limit the amount of signal that ends up in the brain for processing. This works like a border crossing. The border security decides whether or not you’re allowed to enter and what you can take with you.
In the context of pain, these gateways can limit the amount of pain signal that continues across the border to the brain. If more pain signal is allowed to pass, the brain perceives more pain. If the pain is stopped at the border, the brain perceives less pain.
Conventional pain medications work by activating the opioid receptors acting as a key gateway for pain transmission to the brain.
CBD has a similar effect, but through a different receptor is known as the vanilloid receptors. These vanilloid receptors are tasked with regulating a specific form of pain caused by either heat or inflammation. CBD has been reported to modulate this vanilloid receptor — leading to a reduction in the pain signals sent to the brain from inflammatory causes such as arthritis, muscle damage, or infection, to name a few.
CBD has other ways it can limit pain transmission as well:
- CBD may reduce inflammation, limiting the initial cause of pain in the body
- CBD acts as an antioxidant, helping the body resist and recover from damage
- CBD relaxes muscle fibers, reducing pain caused by muscle spasms and tightness
More research is needed to fully understand how CBD and other active cannabinoids can block pain. Every year dozens of new research papers are published in an attempt to paint a clear picture of how CBD works, how to get the most benefit from the supplement, and what its limitations are.
(Pain Transmission Pathway to the Brain)
Choosing CBD Oil Companies: How to Differentiate the Good From the Bad
CBD has become a lucrative business. Companies are selling a myriad of different CBD oils and other products in an attempt to cash in on the new health trend. This means there are a lot of excellent products coming to market, but it also means there’s a lot of trash as well. It’s important as a CBD user that you understand what makes a CBD oil good, and what makes it bad so you can avoid wasting your money, or worse — using CBD oils that contain harmful or damaging ingredients.
Let’s cover the most important points to remember when shopping for CBD oil online or in-store.
1. Check the Hemp Source
The source of the hemp used to make the oil is vitally important when it comes to determining which CBD oils are the best. The main reason comes down to the botany of the hemp plant itself.
Hemp is a bio-accumulator — which means it has the tendency to absorb compounds from the soil and accumulate them in its leaves, stems, and roots. The deep taproots of the hemp plant stretch far beneath the soil, pulling out and storing all the heavy metals and other elements it can find in the soil.
This aspect is in part why hemp is so nutritious, but it also means that plants grown in contaminated soils often contain contaminants that can be harmful to your health. Some of the worst offenders are heavy metals — which can build up in the body over time and lead to severe long-term health effects.
You want to avoid consuming heavy metals at all costs.
Poorly grown hemp could contain heavy metals, as well as other contaminants like mycotoxins, or pesticide residues that will end up in the CBD oil after all the processing is complete.
For this reason, it’s important to purchase CBD oil from companies that account for this effect. Only buy from company’s that make an effort to source hemp from organic farms, and take measures to assess every batch of hemp that enters the facility to determine heavy metal, microbial contaminant, and pesticide contamination.
The best hemp sources tend to come from states like Oregon, Colorado, or Alabama, as well as neighboring countries like Canada or Scandinavian countries. These places are all known for having high standards for hemp cultivation, and clean soils.
2. Look for CO2 Extracted Products
Once the company has the hemp, they need to extract the CBD from it. You can do this in many different ways using solvents like ethanol, methanol, hexane, ether, or butane. All of these solvents work to strip the active compounds from the hemp plant and can then be evaporated to leave behind a pure CBD-rich resin.
however, there’s a problem with these solvents.
Even in professional lab settings, it can be very difficult to remove all traces of these solvents from the final product. Most of these solvents are toxic to the human body, even in trace amounts.
Therefore, the best companies are using another method to strop the active ingredients from the starting hemp material. This method uses CO2 placed under high pressure. the high pressure and temperature control convert the CO2 into a phase that’s neither liquid nor gas. This special state is referred to as being supercritical.
Supercritical CO2 acts just like any other solvent, but with one key benefit — as soon as the pressure is relieved, the gas evaporates completely, leaving behind no harmful chemical residues.
when shopping for CBD oil, it’s ideal to look for a company that uses supercritical CO2 to extract the CBD rather than the toxic solvents mentioned above. Supercritical CO2 is very expensive and highly technical — but usually produces a far superior product in the end.
If a company is using harsh solvents like butane or propane (or they don’t tell you anything about their extraction methods), it’s a sign that you should look for another brand.
3. Ask for Third-Party Lab Reports
Every company has the option to send their products to an independent lab or third-party testing.
These laboratory tests check for the entire cannabinoid profile of the extract and are able to detect over 200 common contaminants.
Before a CBD product becomes available for sale, it should pass the laboratory test for potency and purity. If any inconsistencies are shown between different batches of the same product, the company should rework it and send it for analysis once again.
High-quality CBD companies will continually send each batch of product to a lab with no affiliation to the company (called a third-party or independent lab) for testing. These results are then published publicly on the website for customers to view.
The best companies will take this even one step further — adding a database and batch numbers on every bottle of CBD oil so you can view the results for your specific bottle of oil. Third-party testing is now an industry standard.
Always buy your CBD oil from companies that show third-party lab reports on their website. Only then will you know what’s inside the bottle before you even order a product. If the company is producing CBD oil that’s as high quality, as they say, there should be nothing to hide in these lab tests and they should be listed publicly on the company website. If you can’t find them on the site, you can ask customer service for these as well.
If these tests don’t exist, or you can’t track them down from the website or customer service — it’s best to avoid this company and move on to another that takes this important step seriously.
What the Research Says About Using CBD Oil for Pain:
Understanding how CBD works is no simple task. This compound is incredibly complex — working through a number of unrelated receptors around the body, interacting with enzymes, cell membranes, and various other cell structures. This makes studying CBD very difficult.
Nevertheless, there have been thousands of research papers published on medical marijuana — seeking to understand the interaction between cannabinoids like CBD and the human body. A lot of this research specifically focused on the effects of CBD on various forms and causes of pain. Let’s explore some of the results this research has yielded in the context of pain management.
1. CBD Oil for Chronic Back & Nerve Pain
The painkilling properties of cannabidiol have been most thoroughly studied in animal models, as well as a handful of human clinical trials.
One of the best studies we have available on the topic is a meta-analysis published in 2017. This analysis looked at 24 different clinical trials involving 1,334 patients over several years and demographics. These studies all used various forms of cannabis for treating chronic pain. The analysis reports that many of these studies showed a reduction in chronic pain scores by 50% or more (3) — suggesting the cannabis plant to be a potential treatment for chronic pain.
Another clinical trial looked at the effects of a combination of CBD to THC in the treatment of intractable cancer pain. This study found that twice as many people in the treatment group given CBD and THC had a 30% or more reduction in pain symptoms at the conclusion of the trial (6).
Even though more clinical trials on humans are needed to gauge how CBD affects specific forms of pain or other conditions, scientists believe the efficacy of CBD in treating chronic pain is related to its anti-inflammatory effects (3).
2. CBD Oil for Arthritis
CBD has had a lot of research as a potential alternative to prescription and non-prescription pain medications commonly used for alleviating arthritis pain.
Researchers have found a clear link between the endocannabinoid system and the pathophysiology of osteoarthritis, which is a degenerative joint disease associated with chronic pain and inflammation (4).
One of the key areas CBD is thought to support osteoarthritis specifically is through the effects on an enzyme known as 5-lipoxygenase — AKA 5-LOX. CBD has been shown to inhibit this enzyme (7), which converts fatty acids into pro-inflammatory compounds. These inflammatory messengers have been shown to be a key component in the underlying inflammation involved with osteoarthritis (8).
By reducing the underlying causes of arthritis pain, CBD is thought to reduce the overall burden of pain from the condition over the long term.
3. CBD and Multiple Sclerosis (MS) Pain
Due to its antioxidant and anti-inflammatory properties, CBD is a potent neuroprotective — which is how experts believe CBD is able to relieve debilitating MS pain, —which affects roughly 50–70% of patients diagnosed with the condition.
A study conducted on animals at Cajan Institute tested the anti-inflammatory effects of CBD on mice the researchers wanted to find out if CBD can provide a reversed inflammatory response on those cells. After ten days, the researchers found a reduction in inflammatory markers with a rodent encephalitis model designed to imitate the impact MS has on the body (5).
More research is needed to see exactly how these effects are translated to humans. Currently, there are 23 clinical trials currently underway, or planned within the next 12 months seeking to explore the effects of CBD on MS.
4. CBD Oil in Sports: Injuries & Muscle Endurance
Cannabidiol can be applied in two different ways when it comes to pain and physical activities. For example, when you administer CBD orally in the form of oil as a post-workout, it helps alleviate the muscle inflammation that troubles athletes once they go beyond the edge again.
If, however, you’re suffering from an injury, it’s best to apply CBD topically. Its anti-inflammatory and neuroprotective properties allow the cannabinoid to relieve pain and improve regeneration capacities.
Does CBD Have Any Side Effects?
The main reason why parents are so enthusiastic about CBD is that this cannabinoid is completely non-intoxicating, doesn’t cause addiction, and has only a few mild side effects when taken at excessive doses.
Research shows that even doses up to one and a half grams have no severe side effects on human health (9).
Despite being a notoriously safe supplement, there are some side effects of using CBD in high doses. Let’s cover the most common side effects people report from using CBD:
- Brain fog
- Reduced appetite
- Mood changes
- Diarrhea or constipation
- Dizziness or lightheadedness
- Drowsiness or fatigue
- Dry mouth
- Nausea and vomiting
The most common side effect by far, like other forms of cannabis, is dry mouth. This is best managed by taking your CBD oil along with some juice like pineapple or orange juice.
Another common side effect is lowered blood pressure, which may trigger another unwanted reaction — lightheadedness. This side effect is important to consider if you suffer from low blood pressure already or are taking blood pressure-lowering medications.
Always consult your doctor before using CBD or other cannabis extracts if you’re taking prescription medications or have underlying medical conditions.
In Summary: Buying CBD Oil For Pain
As CBD becomes more popular around the world, scientists are publishing new research on cannabinoids on a near-weekly basis. As time goes on, experts are mapping out the complicated mechanisms CBD and other hemp derivatives are using to support both acute and chronic pain of all different origins.
Here are the main takeaways from the current research:
- CBD inhibits inflammation at several different levels
- CBD offers antioxidant support
- CBD may relieve muscle tension and inflammation
- CBD interacts with the vanilloid receptors in the brain responsible for regulating inflammatory pain transmission
When it comes to pain, CBD appears to target the cause of the problem instead of just masking its symptoms.
Getting relief on so many levels and without any harmful side effects or risk of addiction is the reason why CBD oil has become so popular over the past half a decade.
I hope this guide has managed to clear up any confusion regarding CBD oil and pain, and given you the insight necessary to find the right CBD oil for the job.
Have you tried CBD oil for chronic pain? Did you feel any difference? Let me know in the comments below!
- Brand, E. J., & Zhao, Z. (2017). Cannabis in Chinese Medicine: Are Some Traditional Indications Referenced in Ancient Literature Related to Cannabinoids?. Frontiers in pharmacology, 8, 108.
- Alger B. E. (2013). Getting high on the endocannabinoid system. Cerebrum: the Dana forum on brain science, 2013, 14.
- Aviram, J., Samuelly-Leichtag, G. (2017) Efficacy of Cannabis-Based Medicines for Pain Management: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Pain Physician, 20(6), E755-E796.
- Bruni, N., Della Pepa, C., Oliaro-Bosso, S., Pessione, E., Gastaldi, D., & Dosio, F. (2018). Cannabinoid Delivery Systems for Pain and Inflammation Treatment. Molecules (Basel, Switzerland), 23(10), 2478.
- Elliott, D. M., Singh, N., Nagarkatti, M., & Nagarkatti, P. S. (2018). Cannabidiol Attenuates Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis Through Induction of Myeloid-Derived Suppressor Cells. Frontiers in immunology, 9, 1782.
- Johnson, J. R., Burnell-Nugent, M., Lossignol, D., Ganae-Motan, E. D., Potts, R., & Fallon, M. T. (2010). Multicenter, double-blind, randomized, placebo-controlled, parallel-group study of the efficacy, safety, and tolerability of THC: CBD extract and THC extract in patients with intractable cancer-related pain. Journal of pain and symptom management, 39(2), 167-179.
- Takeda, S., Usami, N., Yamamoto, I., & Watanabe, K. (2009). Cannabidiol-2′, 6′-dimethyl ether, a cannabidiol derivative, is a highly potent and selective 15-lipoxygenase inhibitor. Drug Metabolism and Disposition.
- Lascelles, B. D. X., King, S., Roe, S., Marcellin‐Little, D. J., & Jones, S. (2009). Expression and activity of COX‐1 and 2 and 5‐LOX in joint tissues from dogs with naturally occurring coxofemoral joint osteoarthritis. Journal of orthopaedic research, 27(9), 1204-1208.Chicago
Nina created CFAH.org following the birth of her second child. She was a science and math teacher for 6 years prior to becoming a parent — teaching in schools in White Plains, New York and later in Paterson, New Jersey.
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10 Best CBD Oil for Arthritis: Top CBD Brands Reviewed 2022
Arthritis is a severe and debilitating condition that can affect people of all ages (although it’s more prominent in older individuals). The latest statistics from the Centers for Disease Control (CDC) reveal that up to 58.5 million Americans over 18 had some form of arthritis in 2015.
But an aging population coupled with the repetitive daily tasks we perform—such as computer work or physical labor – likely means the number will be much higher now in 2022. Alarmingly, the CDC predicts that arthritis patients will hit 78.4 million by 2040.
Numbers aside, it’s pretty clear that arthritis poses a considerable risk to people’s health, and it’s not going away anytime soon.
Although research is still ongoing, there’s strong anecdotal and preliminary evidence suggesting CBD may help address some of the symptoms associated with arthritis. As a result, cannabidiol may be a viable alternative for those concerned about medication side effects or dependence on painkillers.
To effectively address arthritis symptoms, you need a CBD oil that’s potent, pure, and safe. Unfortunately, there are now thousands of brands, making it hard to find quality products. We’ve compiled our ten best choices for CBD oil based on several benchmarks to measure quality, strength, safety, and transparency to narrow down the list.
Is CBD Oil Good for Arthritis?
We can’t conclusively say CBD oil is good for arthritis, but the ever-growing pile of preliminary research seems to support that conclusion. It’s also important to consider the mounds of anecdotal evidence that poured in long before experts took CBD seriously. Judging by the number of people who use CBD for arthritis pain and inflammation, the case for cannabidiol gets stronger every day.
For example, an Arthritis Foundation poll surveyed several arthritis patients, revealing some surprising information. According to the survey, 79% of respondents “are currently using CBD, have used it in the past or are considering using it.” Meanwhile, 29% say they currently use it for arthritis symptoms.
Interestingly, the products used are almost evenly split between oils and creams. Of the active CBD users polled, 62% use liquid CBD (oils, tinctures, beverages), while 55% use topical CBD products (creams, balms, lotions).
How CBD Oil Helps with Arthritis
If you plan to try CBD oil for arthritis, it’s helpful to understand how CBD oil helps with arthritis. The mechanism of action is a lot more complex than with other cannabinoids, like THC. But that’s one of the many reasons CBD is so versatile.
Most cannabinoids bind to the CB1 and CB2 receptors that form our endocannabinoid system. This network of receptors and internally-produced cannabinoids keeps our body in balance or “homeostasis.”
THC, for example, binds to both the CB1 and CB2 varieties. Some cannabinoids bind to one or the other. CBD, however, has little affinity for either. Instead, it works through different receptor pathways, including:
● GPR-55 orphan receptors
● TRPV1 vanilloid receptors
● PPAR receptors
● Serotonin receptors
Those pathways serve several functions, including pain regulation, appetite, sleep, and mood to name a few. In the case of arthritis, however, the TRPV1 or “vanilloid” receptors are primarily responsible for mitigating the condition’s symptoms. Researchers induced inflammation in rat subjects during a 2009 study published in the British Journal of Pharmacology.
Based on the observations, CBD’s interaction with the TRPV1 receptors contributed to the anti-inflammatory benefits that also helped reduce pain.
Inflammation is a textbook arthritis symptom inevitably accompanied by pain. Evidence suggests that CBD may help reduce joint pain related to arthritis. For instance, a 2017 research paper in the academic journal Pain studied the anti-inflammatory properties of CBD. Experts applied a CBD-infused topical on rats with osteoarthritis. Although the rodents didn’t show immediate improvement, observers noticed a significant reduction in inflammation by the 14th day of their experiment.
Analgesic 2019 Gallup poll shows 14% of Americans use CBD. But out of all the potential symptoms, 40% of those CBD consumers—the most significant chunk—use it for pain.
This pattern is even more prominent when you look at the Arthritis Foundation’s poll we covered earlier. That survey determined 94% of CBD users with arthritis took cannabidiol for pain.
But one notable piece of research is a 2008 review of existing literature by famous cannabis researcher and medical expert Ethan Russo. Russo is known for “Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects,” a paper where he proposed and explained the synergistic “entourage effect” that we frequently refer to today.
Russo examined studies on synthetic (prescription) cannabinoids and external cannabinoids (phytocannabinoids). Unsurprisingly, he concluded that, based on existing evidence, CBD and other cannabinoids might help manage chronic pain.
CBD was far from mainstream in 2008, but subsequent research—such as that mentioned above—has helped support Russo’s conclusions.
Best CBD Oil for Arthritis: Top CBD Brands Reviewed
If you’re looking to try full-spectrum CBD oil for arthritis pain, it’s hard to find the right product—especially if you’re new to CBD. You need a clean, tested, potent CBD oil for the best results.
To help determine the best CBD oil for arthritis, we’ve compiled a list of top ten vendors based on our objective benchmarks (more on that later).
1. Colorado Botanicals: Best CBD Oil for Arthritis
Colorado Botanicals was established in 2017, offering a trustworthy and effective line of inexpensive Full and broad-spectrum CBD products. Today, they carry an even more extensive selection of hemp supplements, but they have never wavered from their commitment to transparency, safety, and quality. We’re proud to give Colorado Botanicals our top spot as the Best CBD Oil for Arthritis.
Colorado Botanicals offers the best CBD oil for pain (or other possible uses). But we’re not the only ones to notice. Observer and Discover Magazine chose Colorado Botanicals as their top pick as Best CBD Oil and Best CBD Oil for Pain, respectively.
But Colorado Botanicals advantage isn’t just what you see on their shelves. Behind the scenes, those products are backed by quality assurance, sustainable farming, independent testing, and lab-grade production.
CO2 extraction is becoming the primary approach to quality CBD oils. It leaves no trace solvents, making it cleaner – albeit more complicated – than other methods. Unfortunately, the process also destroys many terpenes, cannabinoids, and other beneficial compounds. Typically, vendors artificially add terpenes from other plants to make up for the loss.
However, Colorado Botanicals perfected a proprietary CO2 extraction technique followed by an unmatched purification process that maximizes terpene, cannabinoid, and flavonoid retention for an all-natural product.
Colorado Botanicals full-spectrum CBD oil ranges in potency from 300 to 3,000mg of CBD per 30 ml bottle, but their 750mg Full-Spectrum CBD Oil—at 25 mg/ml—is strong enough to meet the needs of an average CBD user.
The already low price gets better with repeat shipping at a 15% discount.
Based in Denver, Colorado, CBDistillery has grown by leaps and bounds since its founding in 2016. CBDistillery focuses on quality sourcing. They use Colorado hemp grown through “natural farming practices,” although they never mention “organic.” The vendor is also certified by the U.S. Hemp Authority.
All of the company’s CBD oils are very affordable. Veterans and active military personnel may further offset the cost with CBDistillery’s 30% military discount.
Regular customers can also save money by subscribing to a 20% discount on every order.
CBDistillery offers excellent value along with a range of CBD extract products. However, we feel the best option is their mid-range product. CBDistillery’s 1,000mg Full-Spectrum CBD contains 33 mg/ml of CBD, allowing it to address mild to moderate symptoms.
3. NuLeaf Naturals
Established in 2014, NuLeaf Naturals keeps its products pure and simple. Although they were strictly CBD-focused, their offerings expanded to CBG, CBN, and CBC oils. NuLeaf’s approach to hemp CBD is similar to that of Colorado Botanicals. Both prefer to focus on purity rather than flavors and other proverbial bells and whistles. One thing they haven’t done is expand beyond oils, topicals, and capsules. But this isn’t necessarily a bad thing. Rather than branch out to new options, they continue refining and perfecting the products that made them successful. Unfortunately, this can limit their customer base, but those that are loyal can expect to enjoy some of the purest CBD oils available. If you’re looking to try Nuleaf Naturals CBD oil, their 900mg Full-Spectrum CBD Oil is a perfect mid-range starting point.
4. Lazarus Naturals
Based out of Seattle, Lazarus Naturals grows its organic hemp in Oregon.
They offer CBD and other cannabinoid extracts in various sizes and options. Like most premium CBD vendors, they’ve since expanded into other extracts, adding CBG and CBN to some of their formulations.
One thing that stands out about Lazarus Naturals is their price. Customers can pick up a bottle of full-spectrum 2,400 mg 60 ml CBD oil for just $120.00. Lazarus Naturals also has one of the best return policies possible. You can return your unwanted items for free with a prepaid shipping label up to 90 days after receiving them.
We recommend the Lazarus Naturals High Potency 1,500mg Tincture. All of the oil products in this line contain 50 mg/ml, so our choice is based on volume and price.
5. Charlotte’s Web
Charlotte’s Web is one of the most established CBD brands. Originally opening in 2012, their high-CBD cannabis strains put cannabidiol on the map. The brand rose to prominence after a story went public about Charlotte Figi, a young girl whose severe epilepsy was controlled by the company’s CBD oil.
Charlotte’s Web isn’t the cheapest brand, but it’s not prohibitively expensive either. It helps that they offer a 20% discount for subscribers and an assistance program for veterans.
Charlotte’s Web sells 30 or 100 mg bottles in 7, 17, 25, 50, and 60 mg/ml concentrations. In our view, however, the best mid-range choice is their THC-Free CBD Oil at 25 mg/ml. The broad-spectrum product is perfect for moderate users and carries no THC.
6. Joy Organics
Joy Organics is among the few who can say their hemp is USDA Certified Organic, the highest tier possible.
Like CoBo, Joy says they use a proprietary CO2 extraction method that maximizes natural hemp compound retention. Of course, you can see that with lab test results available on each product page.
The company also offers decent potency options, ranging from 15 mg/ml to 75 mg/ml – all at surprisingly affordable prices. Customers can save even more with Joy’s 20% discount for subscribers.
We highly recommend Joy Organics Full-Spectrum 1350 MG Fresh Lime Organic CBD Tincture, popular among customers looking to try CBD for arthritis pain.
At 45 mg per serving, the product’s potency offers an excellent balance for beginners and intermediate CBD enthusiasts.
cbdMD embodies what success in the industry should look like. Opening in 2015, their company grew exponentially and now offers a diverse selection of CBD oils, edibles, skincare products, and more.
As far as potency is concerned, cbdMD tops our list. Their most potent product (7500 mg) contains a staggering 250 mg/ml in a 30 ml bottle – far above the 100 mg/ml cap we’ve seen so far with other companies.
Considering what they offer, cbdMD is quite affordable, with their strongest oil retailing for just $209.99 – a price that’s much lower with their 30% subscriber discount. The cbdMD Premium 750 mg CBD Oil Tincture is a solid medium-dose product that may help people who are trying to address arthritis pain and other symptoms. At 25 mg/ml, the concentration isn’t excessive for beginners yet also adequate for those with moderate needs.
Established in 2017, Medterra is a bit of a youngster compared to some of its competitors. But despite its comparative inexperience, the CBD company has a lot to offer. Medterra only carries a handful of CBD products, but their formulas reflect the more advanced recipes that many companies adopted. Certain lines include other beneficial ingredients, like CBG and nutritional supplements.
What truly stands out about Medterra is its commitment to education. Their site is crammed with resources and news for beginners new to CBD. With such tools, it’s easy for anyone to get their feet wet as they enter the ever-growing world of hemp-derived CBD health supplements.
Customers looking for full-spectrum CBD oil can choose Medterra’s True Full-Spectrum oil at 50 mg/ml. The product is only available in 50 and 100 mg/ml doses, with 2 mg of THC per serving.
9. Royal CBD
Royal CBD’s commitment to quality is pretty straightforward. As their slogan states: “no room for mediocrity,” it’s evident that they take their products seriously. Despite the rather intense tone, it offers a sense of reassurance. Their commitment to quality is transparent, with CO2 extraction, natural sourcing, and third-party tests integral to their business.
Royal CBD offers decently potent oils. At up to 83 mg/ml in broad-spectrum and full-spectrum CBD options, they sit in the upper tiers but don’t approach the solid 100 mg/ml of CoBo, or cbdMD’s 250 mg/ml concentration.
Royal CBD’s 1,000 mg Full-Spectrum CBD Oil is a good balance between price and potency – although, at $129.00, it’s a bit expensive. Still, the product contains 33 mg/ml of CBD, an excellent mid-sized dose.
10. Green Roads
Green Roads may not have the same chops as some bigger names, but it makes up for that with its experience, knowledge, and exciting backstory.
Founded in 2013 by pharmacist Laura Fuentes, she was inspired to enter the industry after a friend with health issues approached her for help. What started as a side gig formulating products in her spare time soon became the thriving business we see today.
Green Roads carries isolate, broad-spectrum, and full-spectrum tinctures. We recommend Green Roads 1500mg Broad Spectrum CBD Oil, which contains a solid 50 mg/ml of CBD.
How We Chose the Best CBD Oil for Arthritis
Whether you’re looking for arthritis pain or other chronic pain management, you need the best CBD products. But sorting through the sea of companies is challenging and time-consuming – so we did that for you.
To remain objective, our rankings are based on a specific set of criteria, which determines a CBD vendor’s rank on our list.
An easy way to find the best CBD companies is through company reputation. It’s easy for any CBD retailer to say they’re the best or post reviews on their websites. However, we avoid potentially biased sources and instead focus on independent forums, like Reddit or Trustpilot.
That being said, some companies – while excellent – are still building a place in the market, so company reputation doesn’t carry the same weight as some of our other benchmarks.
Third-Party Lab Reports
Third-party lab reports are necessary for a CBD retailer to make it anywhere near our list. These tests are critical for transparency and safety. Without concrete proof, any vendor can assure us of their products’ quality, accuracy, and purity.
Lab reports should be clear, easy to read, and from a reputable third-party lab. Some vendors do their in-house testing, but that’s a recipe for bias. The tester’s information is supposed to be listed on the test document, making it easy to check with a simple Google search.
Product testing is tied to third-party lab reports. Lab reports won’t exist without a testing process – unless they’re forged, which sadly has been known to happen. Like reports, testing is an absolute must-have. Hemp extracts can contain any number of contaminants, like bacteria, fungi, and heavy metals. It’s also impossible to confirm CBD content without testing the extract first.
Any vendor that doesn’t test its products should be avoided.
While company reputation focuses on brand recognition through customer volume, customer reviews determine whether a vendor—known or obscure—is worth supporting. Again, we base our evaluations on independent feedback from sources like Reddit or other consumer review forums.
Although we understand every company has its share of bad ratings, a large customer base and overwhelmingly positive responses indicate a reputable business.
CBD Oil for Arthritis FAQs
How much CBD oil to take for arthritis?
The amount of CBD oil to take for arthritis is tricky to determine. Conventional medications receive extensive study and are designed to behave a certain way, making dosing easy and predictable.
CBD, however, hasn’t had the same level of research as any medicine you’ll find at your local drugstore – prescription or otherwise. And the information we do have only indicates that textbook CBD dosing is all but impossible.
Many factors affect the correct dose, including:
● Sensitivity (to CBD)
Our endocannabinoid systems are also unique to each of us, further complicating the dosing issue.
Start Low and Go Slow
CBD is biphasic, meaning that too much CBD is just as ineffective as taking too little. That’s why it’s essential to follow the old cannabis adage, “start low and go slow.” If you’ve never experienced CBD before, start with the smallest dose possible – around 2.5 to 5 mg. Increase that dose gradually over several days until you notice results.
When is the best time to take CBD oil for arthritis?
If you suffer from constant flare-ups, your goal will be to keep a steady supply of CBD in your body to hopefully mitigate the pain and inflammation. There’s no right or wrong time to take CBD, but consumers find it works better when taken with food.
Eating something fatty, like peanut butter, also helps speed up absorption since CBD (like all cannabinoids) needs some kind of lipid to carry it.
What is the best way to take CBD for arthritis?
The best way to take CBD for arthritis is through oral ingestion. This approach allows CBD to provide a more generalized anti-inflammatory and analgesic effect. Oils aren’t the only option. Many CBD edibles are available that make taking CBD easier for those who aren’t fans of the “hempy” oil flavor. To that end, CBD gummies are a fantastic alternative.
If you want the best CBD gummies for pain, keep our benchmarks in mind while shopping around. However, topicals are also a practical option for fast, focal relief of joint pain and inflammation. Although they’re not as long-lasting as CBD oil, topicals work almost instantly, right where you need them.
Both oils and topicals are excellent products, but using them together is the best way to prevent arthritis symptoms and quickly address them should they arise.
Does CBD have side effects?
Yes, CBD has side effects. Fortunately, they’re rare and relatively mild. Some examples include:
● Appetite change
● Mood changes
One concern is CBD’s potential interaction with certain prescription medications, such as antiepileptic drugs (AEDs). If you’re on any medicines, speak to your doctor or specialist before trying CBD.
Conclusion: Best CBD Oils for Arthritis of 2022
It’s tough to find the best CBD oils for arthritis. Shopping for the right one can be overwhelming with so many products, brands, and sources. The easiest way is to look for specific indicators of quality, credibility, and safety.
But the world of cannabinoid hemp supplements is rapidly expanding. CBD laid the groundwork, which has since paved the way for other related products. Cannabigerol (CBG) several brands—like those above—created some of the best CBG oil available, which could further help mitigate arthritis symptoms.
While there’s no guarantee CBD will work for you, being a smart shopper increases your chances of seeing positive results.
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