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Best cbd oil full spectrum for anxiety

7 Best Full-Spectrum CBD Oils in 2022 – Natural Relief for Pain, Inflammation & Anxiety

CBD is a natural compound that can be used to help with a wide variety of issues, from anxiety to pain relief and CBD oil is becoming more and more popular as people learn about its benefits. Full-spectrum CBD oil products contain all the beneficial natural components of the hemp plant, so it offers the full goodness of hemp, unlike broad-spectrum and CBD isolate products that use slimmed down versions of hemp extract.

But with so many different CBD oils on the market, it can be hard to know which one is best for you. We did the work for you by combing through the internet to find the highest-quality full-spectrum CBD oils available. Read on to discover the 7 best full-spectrum CBD oils that we recommend to our readers. We’ll also help you determine which full-spectrum CBD product might be best for you based on your needs and preferences.

7 Best Full-Spectrum CBD Oil Brands

    – Editor’s Choice – Close Second – Honorable Mention – Great Discounts – High Bioavailability – Many Flavors
  1. NuLeaf Naturals – Informative

7 Best Full-Spectrum CBD Oil – Reviews

1. CBDfx – Editor’s Choice


  • USA-grown organic hemp
  • Third-party tested
  • 60-day money-back guarantee
  • Free Shipping Available
  • Mild taste


Company Overview

Founded in 2014, CBDfx has been making a name for itself as a reputable company in the CBD space and has become one of the most well-known CBD brands. Their full-spectrum CBD is derived from organic USA-grown hemp and their products go through a third-party lab test for potency and purity. These results are provided for customers to look at on their website before purchase. They use CO2 extraction methods to ensure no solvents end up in the final product.

About the Product

CBDfx’s full-spectrum CBD products offer a wide range of CBD benefits. You can purchase oils that have added ingredients like melatonin for sleep or brain-boosting mushrooms for better focus. The products are highly reviewed by over 23,000 customers and most people agree that they enjoy the lack of strong taste in the oils they’ve purchased from CBDfx.

There are several perks available like subscribe and save features and discounts on bulk or bundle orders. Their CBD products are also medically reviewed and come in several different potencies so you can find the perfect dose for you.

Why We Recommend It

The CBDfx full-spectrum tincture is a great choice for those just starting out with CBD. It’s a mild and easy-to-use product with a pleasant taste. Their third-party testing and medically reviewed products give the company credibility so you know you can trust the products you receive. CBDfx also offers a 60-day money-back guarantee, so you can try it out without any risk.

2. CBDistillery – Close Second


  • USA-grown hemp
  • Many options
  • 60-day money-back guarantee
  • Third-party lab tested


Company Overview

CBDistillery uses Colorado-grown hemp for its full-spectrum CBD products and all the farms they work with use modern and pesticide-free farming practices. Their CBD products are third-party lab tested for potency and purity with results available to review before purchase. They use CO2 extraction methods to ensure the purest products, and they give you lots of options when it comes to picking a full-spectrum CBD oil.

About the Product

The full-spectrum oils offered by CBDistillery come in several different potency options, which makes this brand a great choice for anyone looking to dial in their perfect dose. They also have a wide range of flavors to choose from, plus an unflavored option for anyone who prefers a natural taste to their CBD products. You can also choose oils that have added terpenes or other nutrients to boost the effects of your CBD and get added benefits.

Why We Recommend It

CBDistillery is a great choice for full-spectrum CBD oils. They offer a wide range of potency and flavor options, which makes them a great choice for anyone who hasn’t decided on their top favorite yet. They also offer a 60-day money-back guarantee so you can shop with confidence. All of their products are third-party lab tested for potency and purity, so you can trust that you’re getting a quality product.

3. Green Roads – Honorable Mention


  • Formulated by a licensed compounding pharmacist
  • Multiple potency options
  • USA-grown hemp
  • Third-party tested


  • Some people aren’t a fan of the taste

Company Overview

Green Roads was founded by a pharmacist after she saw all the positive research coming out about CBD and how it could help so many people with several health conditions. She noticed that there were a lot of bad CBD products on the unregulated CBD market and wanted to fix that by offering high-quality CBD to everyone who needs it. Green Roads makes their full-spectrum CBD oil using USA-grown hemp and all-natural ingredients. The products are third-party tested, and the results are made available to view on the website for transparency.

About the Product

Green Roads’ full-spectrum CBD products come in a wide range of potencies, from 10 mg CBD per ml to 50 mg per ml, making it a great choice for anyone who knows what potency they need. These oils are made with natural ingredients and lack artificial colors and flavors. The oil is vegan, gluten-free, and formulated by a pharmacist. If you’re interested in CBD isolate, this company offers it, too. Green Roads is unique in that they offer daily dose packets that you can buy that have a single dose in them for convenience. They also have generous discounts for first responders, teachers, and veterans.

Why We Recommend It

Green Roads’ full-spectrum hemp-derived CBD products are a great choice for those looking for a high-quality product. The company was founded by a pharmacist, so they have a deep understanding of CBD and how it can help people. They use only USA-grown hemp and all-natural ingredients in their products. The full-spectrum CBD oil products are third-party tested for potency and purity, and they offer generous discounts to first responders, teachers, and veterans.

4. Absolute Nature CBD – Great Discounts


  • Generous discounts
  • Third-party tested
  • USA-grown hemp
  • Organic and vegan ingredients


  • Only one potency is available

Company Overview

Absolute Nature CBD was founded with a mission to provide the best all-natural full-spectrum CBD products to enhance people’s lives with the benefits of CBD. They noticed the lack of quality and transparency that was running wild in the CBD market and wanted to do their part to provide safe and effective CBD to anyone who wants it. They value transparency and make all third-party lab results available for viewing on their website. They also use natural, organic, and vegan ingredients as well as USA-grown hemp from Colorado.

About the Product

The full-spectrum CBD oil offered by Absolute Nature CBD is USDA Certified Organic and contains a host of other beneficial ingredients like terpenes, minerals, fatty acids, and vitamins that can be found in the hemp plant. With only two ingredients (CBD hemp extract and MCT oil), this full-spectrum CBD oil tincture is about as pure and natural as you can get.

This company has a lot of positive reviews from customers who say the customer service is fantastic. The company accepts returns on its products with a 30-day money-back guarantee and they also offer generous discounts for veterans, first responders, low-income households, and anyone who has autism, epilepsy, or anyone on long-term disability.

Why We Recommend It

Absolute Nature CBD is a great choice for full-spectrum CBD oil because they are transparent about their ingredients and use third-party testing. They use only organic and vegan ingredients as well as USA-grown hemp, which makes them a great choice for anyone looking for a clean and pure product. They have generous discounts for veterans, first responders, low-income households, and anyone who has autism, epilepsy, or anyone on long-term disability. Anyone who falls into any of those groups could benefit greatly by purchasing from Absolute Nature CBD.

5. CBD American Shaman – High Bioavailability


  • High bioavailability
  • USA-grown, organic hemp
  • Third-party tested
  • 45-day money-back guarantee


  • Only one potency option

Company Overview

CBD American Shaman is a family-owned business with a mission to provide the highest quality CBD products to the public. They use only organic, USA-grown hemp in their products and strive to be eco-friendly. The company follows the highest standards to produce an effective, safe, and trustworthy hemp extracted CBD while using proprietary nanotechnology that makes their oil nine times more bioavailable than other nonprescription CBD products on the market. CBD American Shaman also shows that they care about their customers by offering generous discounts for veterans, people in need, or in low-income households.

About the Product

CBD American Shaman’s water-soluble full-spectrum CBD oil is much easier for your body to absorb than other CBD oils on the market, meaning you will reap more benefits from their oil than oils made by other companies. Their organic, vegan, and gluten-free oil comes in three different flavors, and you can purchase it at a strength of 10 mg per ml of CBD.

Why We Recommend It

CBD American Shaman’s full-spectrum CBD oil is one of the most bioavailable CBD oils on the market. It is made with organic, USA-grown hemp and is vegan and gluten-free. The company also offers generous discounts for veterans and people in need, as well as a money-back guarantee so you can shop without the fear of wasting money if you decide the product isn’t for you.

6. Charlotte’s Web – Many Flavors


  • Best flavors
  • Organic and USA-grown hemp
  • Added flavonoids
  • Natural ingredients
  • Third-party tested


  • Customer service can be hard to get a hold of

Company Overview

Charlotte’s Web was founded in 2011 to save a child who suffered over 300 grand mal seizures a day. The brand has been making a name for itself as one of the most reputable brands in the CBD space ever since. This company uses USA-grown and organic hemp as well as all-natural ingredients for their full-spectrum CBD oil, making their products healthy and pure. Each batch is tested by a third-party lab and those results are made available on the company’s website for full transparency.

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About the Product

Charlotte’s Web’s full-spectrum oils come in several different potencies and are made from organic hemp that is pesticide-free and free of heavy metals, and chemical fertilizers. The terpenes and flavonoids included in their CBD oils will help boost the entourage effect that full-spectrum CBD oil gives you, so you will get more benefits out of your oil. The company also offers broad-spectrum CBD and CBD isolate for anyone who would like to try them. Customer reviews mention that they like the taste of Charlotte’s Web products over other products on the market.

Why We Recommend It

The full-spectrum CBD oils available at Charlotte’s Web are some of the best-tasting oils on the market. They are also made with organic and USA-grown hemp, as well as all-natural ingredients. Charlotte’s Web is also one of the most reputable CBD brands available, and they offer full transparency by making the results of their third-party lab testing available for viewing on their website. Anyone who wants a great-tasting and effective oil from a trustworthy brand will benefit from buying from this brand.

7. NuLeaf Naturals – Informative


  • Wide potency range
  • Fast shipping
  • Organic, USA-grown hemp
  • Organic


  • No flavor options

Company Overview

NuLeaf was founded in 2014 by health-conscious lovers of plant-based medicine who were concerned about the wide range of untrustworthy CBD products that were emerging on the market. Its mission is to provide CBD products that are clean, healthy, and effective so that everyone can reap the benefits of a happier and healthy life with the aid of CBD. They use third-party testing and make the results available on their site so all customers can see what they’re buying before they click the order button.

About the Product

The full-spectrum oil offered by NuLeaf is made with whole-plant hemp extract and organic virgin hemp seed oil. With only these two ingredients, NuLeaf CBD oil is one of the most natural products that you can find on the market today. The CBD is pulled from the hemp using a CO2 extraction method – the cleanest way of extracting CBD from hemp plants. You can purchase their full-spectrum CBD oil in a wide range of sizes, from 300 mg CBD to 6000 mg CBD.

Why We Recommend It

NuLeaf CBD oil has a wide range of potencies to choose from, making it an excellent choice for people who want to experiment with different potencies to find the one that works best for them. They also offer full transparency by making their third-party lab test results available on their website. Additionally, they use only organic and USA-grown hemp in their products, making them a safe and healthy choice.

How We Chose Our Top Full-Spectrum CBD Products

Finding the best full-spectrum CBD oil on the market isn’t always easy, especially given the lack of regulation in the CBD space. It’s even more challenging if you aren’t sure what qualities to look for when searching for your CBD. We set out to find the best full-spectrum CBD oils by judging each product in an unbiased way using these four criteria:

  1. Potency range: Not everyone needs the same dosing of CBD, and it can be difficult to find your perfect dose when you only have one potency available. Giving customers options adds to convenience and can also end up saving customers money. That’s why companies with multiple doses available got more points from us.
  2. Transparency. Since the CBD market is largely unregulated, it’s important to be able to trust a brand when they tell you what’s in their product. The best way to get that trust is by being as transparent as possible and granting customers easy access to third-party lab results. Companies that made their results easy to find scored more points.
  3. Ingredients: CBD is the most important ingredient when it comes to full-spectrum CBD oil, but where that ingredient comes from matters. Any added ingredients matter, too. Products made with organic hemp and no added artificial ingredients are considered healthier and get more points from us.
  4. Company reputation: You can tell a lot about a company’s products by looking at their reputation. If a brand has a lot of good reviews and satisfied customers, you can trust that you will have a better chance of being satisfied by the product you buy, too. For that reason, CBD companies with more positive reviews scored more points for this list.

What Are the Different Types of CBD Oil?

CBD oil is a type of cannabinoid oil that is derived from cannabis. CBD can be made from either marijuana or hemp plants, but is typically made from hemp plants because, by definition, they have very low amounts of THC so do not cause any psychoactive effects. There are three primary types of CBD oil: full-spectrum CBD oil, broad-spectrum CBD oil, and CBD isolate.

Full-spectrum CBD oil is made from the whole hemp plant, while broad-spectrum CBD oil is made from the plant but without the THC. CBD isolate is what the name implies – pure CBD with no other cannabinoids, terpenes, or other natural compounds found in hemp.

Many consider full-spectrum CBD to be the most effective type of CBD, as it contains all the cannabinoids, terpenes, fatty acids and other beneficial compounds found in the plant that help promote what is known as the entourage effect, which boosts the effectiveness of CBD in the body. However, it does contain trace amounts of THC, so it is not recommended for those who may be concerned about drug tests.

Broad-spectrum CBD oil is a good choice for people who want the benefits of full-spectrum CBD without any THC. Since it still contains all other cannabinoids, this type of oil can still help to promote the entourage effect.

CBD isolate is good for people who are looking for the pure effects of CBD, since isolates contain nothing but CBD. Ideal for those who absolutely can’t ingest any THC, CBD isolate products are most often found in powder form that makes it easy to mix with food and drinks.

What Are the Benefits of CBD Oil?

CBD oil has a variety of benefits, including reducing anxiety, relieving pain, and treating seizures. CBD oil is also effective for treating other conditions like the side effects of cancer treatment and Alzheimer’s disease.

Many studies have found that CBD can help regulate blood sugar levels to combat diabetes, reduce inflammation related to arthritis, and improve heart health. CBD oil can also help to improve sleep quality and reduce stress levels. CBD has also been found to improve sleep and boost cognitive performance.

How Do I Choose the Right Full-Spectrum CBD Oil?

There are thousands of different full-spectrum oils on the market today, which makes it hard to find the perfect one for you. But even if you’re completely new to buying CBD, there are a few things you can look out for to make it easier for you to decide on the right product.

First, consider the potency of the full-spectrum CBD oil. The potency is the amount of CBD in the product, and it is typically measured in milligrams (mg). If you have never used CBD before, you might want to start with a product that has low potency and work up from there. On the other hand, if you’re an experienced CBD user, you might want to look for a full-spectrum CBD oil that has a high potency, as this means that you will get more CBD per dose.

Second, consider the price. full-spectrum CBD oils can vary in price significantly, so you’ll want to find one that fits into your budget. Keep in mind that a high-quality product won’t be cheap, but it shouldn’t cost you a month’s salary, either. Try to find an oil that is competitively priced – like any of the products included in this review.

Third, consider the company that is selling the full-spectrum CBD oil. Not all companies are created equal, and you’ll want to do your research on the company before you buy from them. Look for a company that has a good reputation and that sells high-quality products. All of the companies on this list are reputable and trustworthy, so you know you’ll get a great product from them.

Finally, consider the ingredients in the full-spectrum CBD oil. Full-spectrum CBD oils contain all the cannabinoids and terpenes found in the hemp cannabis plant, so you’ll want to make sure that the oil you’re considering contains all of these ingredients. If an oil doesn’t contain all of these ingredients, it’s not a full-spectrum CBD oil and you should avoid it. Also, take notice of any added ingredients. Avoid oils with artificial flavors or coloring.

How Do I Use Full-Spectrum CBD Oil?

There are several different ways to take CBD oil, and the best way for you depends on your personal preferences and how you want it to work. You can use CBD oil by taking it by mouth or sublingually. Taking CBD sublingually (putting it under the tongue) is the most common way to take it, as it’s the quickest and most effective way to absorb the CBD.

You can also add CBD oil to your food or drink it straight. This takes a little while longer to absorb since the CBD has to go through your digestive system, but it’s a good option if you don’t want to taste the oil.

Finally, you can also use CBD topically. Many companies make creams, lotions, serums and other topical CBD products that can be applied directly to the skin. This is a good option if you’re looking for relief from pain or inflammation in one specific area of your body.

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Safety and Side Effects of CBD

CBD is a great product that people often turn to for natural relief from pain, anxiety, and other health conditions because it’s considered very safe and rarely has any side effects. However, there are some minor side effects that you might experience when taking CBD, including diarrhea, changes in appetite, and fatigue. Most of the time, these side effects are very mild and temporary and go away within a few days. However, if you experience any severe or persistent side effects, you should stop taking the CBD and consult your doctor.

Also, keep in mind that CBD has been found to interact with several different medications. If you’re taking any medications, you should consult your doctor before taking any of their approved nonprescription CBD products to make sure that there are no interactions. The most common medications that CBD interacts with are blood pressure medications, anti-seizure medications, and antidepressants.

How Does CBD Work?

CBD works by interacting with the body’s endocannabinoid system. The endocannabinoid system helps maintain balance in the body, and when it’s disrupted, it can lead to a variety of health conditions.

When you take CBD, it gets released into your bloodstream, where it travels to receptors in the brain and immune cells. The CBD interacts with the receptors and stimulates your brain to release neurotransmitters like dopamine and serotonin, which can help with pain relief, anxiety, and other conditions. The CBD that interacts with receptors in your immune system helps to block pain signals to the brain and can help with conditions like inflammation and autoimmune diseases.

How Much CBD Should I Take?

The amount of CBD that you should take depends on your individual needs and the condition you’re trying to treat. Most people start with a low dose of CBD and increase it gradually if needed. For best results, you should talk to your health care provider to get their recommendation for dosing.

If your health care provider doesn’t give you a recommendation, start by taking 5 mg full-spectrum CBD oil per day for a week. If after a week, you don’t think you’re getting the full benefits of CBD, increase your dose by 5 mg and repeat for a week. Do this until you reach a good dose that gives you the benefits you’re looking for.

What’s the Difference Between CBD and THC?

CBD and THC are both cannabinoids that interact with your endocannabinoid system, but they have different effects on the body. THC is the cannabinoid that’s responsible for the psychoactive effects that are associated with marijuana. CBD, on the other hand, doesn’t have any psychoactive effects and is considered safe for people of all ages.

Is CBD Legal?

CBD is legal in all 50 states in the US as long as it comes from the hemp cannabis plant and not the marijuana cannabis plant. All products on this list use hemp-derived CBD and are federally legal. However, the laws surrounding CBD can vary from state to state. You should check with your state’s laws to make sure that you’re following the correct regulations.

Is There Anyone Who Shouldn’t Use CBD?

There is limited research on the use of CBD during pregnancy and breastfeeding, so it’s best to avoid using CBD if you’re pregnant or breastfeeding. There is also limited research on the use of CBD in children, so it’s best to avoid using CBD if you’re a child.

Anyone on certain medications that interact with CBD should avoid using CBD products. When in doubt, consult your doctor. They will tell you if CBD is the right choice for you.

Is CBD Addictive?

CBD is not addictive and won’t cause any psychoactive effects. It will not cause dependency and if you stop taking CBD, you won’t experience withdrawal symptoms. For this reason, it’s a safe choice for people who are looking for an alternative to prescription medications that can be addictive or have harsh side effects.

Will Full-Spectrum CBD Make Me Fail a Drug Test?

It is very possible that full-spectrum CBD may make you fail a drug test. Although full-spectrum CBD is made from hemp-derived CBD and is federally legal, it does contain trace amounts of THC – albeit at very small trace levels (no more than .3%).

To be safe, try taking a broad-spectrum CBD or CBD isolate product instead.

Does CBD Oil Expire?

Like all consumables, CBD oil does expire, but it lasts a long time. To extend its shelf life, it’s best to store it in a cool, dark place. CBD oil can last for up to two years if stored properly.

Studies have found that the potency of CBD will start to degrade starting at 6 months, so to make sure you’re getting the maximum benefit from your CBD, don’t buy more than you can use within 6 months.


Full-spectrum CBD oil is a great product that many people use for natural relief from a variety of different conditions. It has a host of benefits and is considered very safe and rarely causes side effects, which is why more people are seeking out CBD to add to their life as a natural remedy every day.

But we know that finding the best full-spectrum CBD oil can be difficult without knowing what to look for. That’s why we put together this review of the best full-spectrum CBD oils on the market. We hope this review has been helpful. If you’re looking to dive into the world of full-spectrum CBD and start enjoying all the benefits it has to offer, we recommend any of the products on this list.

The Best CBD Oil Brands for Anxiety & Depression

In the past several years, CBD has become a popular and natural way for people to help manage their anxiety. What is the best CBD for anxiety? And how does CBD help with anxiety? In this article, we highlight our favorite brands of CBD for anxiety and provide important background information on how to use CBD oils to help manage anxiety and depression.

CBD stands for cannabidiol, and it is one of the active ingredients found in cannabis. Though CBD is a critical component in medical marijuana, most commercially available CBD products are derived from the hemp plant. These products are said to offer a range of personal health benefits, and one of the most significant of those benefits is relief from anxiety.

A Harvard report notes that CBD is commonly used as a way to manage anxiety symptoms, and that those who struggle with various mental health concerns may use CBD to help them combat sleeplessness.

But what does the science really say about using CBD oil for anxiety and depression? And for those who wish to use CBD products to help with anxiety, what are the best CBD for anxiety brands out there?

Does CBD Help for Anxiety?

Studies show that, while CBD doesn’t necessarily alter a person’s baseline anxiety level, it may be useful for reducing experiential anxiety. Indeed, research points to CBD as a potentially effective way to address the symptoms of seasonal affective disorder (SAD), generalized anxiety disorder (GAD), and post traumatic stress disorder (PTSD). Additional research indicates that CBD “has a promising role as alternative therapy in the management of anxiety disorders,” though more clinical testing is needed to verify safe dosage levels.

Based on the available evidence, CBD may potentially help manage the symptoms of anxiety, though it is not a cure. Be sure to consult with your primary care physician or mental health care provider before taking CBD for anxiety and depression if you have any questions or concerns.

Best CBD Oil for Anxiety in 2022

Each product featured here has been independently selected by the writer. You can learn more about our review methodology here. If you make a purchase using the links included, we may earn commission.

  • Best Overall – CBDistillery Strongest Full Spectrum – Spruce
  • Best Full Spectrum – NuLeaf Naturals
  • Best Organic – Cornbread Hemp

How We Chose CBD Product for Calming

When creating our list of the best CBD oils for anxiety and depression, we compared brands and products ib six specific categories.

  • Type of CBD — Does the brand use full spectrum, broad spectrum, or CBD isolate?
  • Strength — How many milligrams of CBD does the oil contain per recommended dose?
  • Source — Where does the get the hemp used in their hemp extract? Is it grown in the U.S.?
  • Flavor — Do they offer multiple flavors, and if so, do they use natural flavoring instead of artificial flavors?
  • Transparency — Is the product tested by an independent third-party lab and do they make the results easy to access?
  • Customer Experience — What are customers saying about the product and if it has helped them manage stress and anxiety?

Learn more about each of the CBD oils on our list below.

Our Complete Reviews & Opinions

Best Overall: CBDistillery

CBDistillery is known for high-quality, pure CBD products, and their full spectrum oil is a great choice to help you relax. All of their products are third-party lab tested and confirmed to be safe and effective. We like their Relief + Relax CBD oil because it is a full spectrum oil that provides plenty of additional active cannabinoids and plant compounds like CBG, CBC, and terpenes to give you the full benefits of the entourage effect.

  • CBD: Full Spectrum
  • Strength: 33 mg CBD per serving (1000 mg per bottle)
  • Hemp source: Colorado

Why buy: We love this strong full spectrum CBD oil for anxiety because it is sourced from non-GMO, U.S. Hemp Authority Certified hemp grown in Colorado. Taking CBD Relief + Relax in the morning may be a great way to support a sense of calm throughout the day.

Strongest Full Spectrum: Spruce

Spruce CBD oil checks all of the right boxes: it’s all-natural, made from USA-grown hemp, and is backed by rigorous third-party lab testing. You can get this lab-grade CBD oil tincture in a range of potencies, ranging from 750 mg to 2,400 mg per bottle. We like that Spruce CBD oil is all-natural, organic, vegan, gluten-free, and contains no artificial flavors, preservatives, or sweeteners. Note that Spruce products may be too strong for entry-level customers.

  • CBD: Full Spectrum
  • Strength: 25 mg to 80 mg of CBD per serving
  • Hemp source: Kentucky and North Carolina
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Why buy: We love that Spruce offers some of the strongest full spectrum CBD products, including their extra strength formula with 80 mg of CBD per serving. We recommend it for experienced CBD users looking for powerful relief from feelings of anxiety and stress.

Best Full Spectrum: NuLeaf Naturals

NuLeaf Naturals CBD oil is about as natural as a CBD tincture can get. It’s made from organic hemp, it’s additive- and pesticide-free, and it’s carefully lab-tested by independent third-party labs. This Colorado-grown, full spectrum CBD offers the full benefits of hemp extract in a natural, organic product. It may be taken daily to help you manage stress and feelings of anxiety by promoting a sense of calm and wellness.

  • CBD: Full Spectrum
  • Strength: 30 mg of CBD per serving (1800 mg per bottle)
  • Hemp source: Colorado

Why buy: We love this strong full spectrum CBD oil because of its simplicity. It contains organic full spectrum hemp extract and organic virgin hemp seed oil. NuLeaf Naturals also provides a consistent concentration of CBD across all bottle sizes to make dosing easier.

Best Organic: Cornbread Hemp

To make their Distilled CBD Oil, Cornbread Hemp extracts CBD only from hemp flowers. This distillation allows the oil to maintain a full spectrum of cannabinoids, with a CBD-to-THC ratio of 27:1. Lower in THC than their Whole Flower oil, this product is better for finding comfort during the day while staying focused and alert. Cornbread Hemp CBD is USDA organic and offers a cleaner tasting oil than some whole plant extracts.

  • CBD: Full Spectrum
  • Strength: 50mg per 1mL serving
  • Hemp source: Kentucky

Why buy: We love this Cornbread Hemp Distilled CBD Oil because it uses whole flower CBD extract for a cleaner product and milder taste. It may be a great way to help ease anxiety during the day without drowsiness or loss of focus. Plus, it’s USDA-certified organic with third-party, ISO certified lab tests on every batch.

Using CBD to Help With Anxiety & Depression: What the Research Says

As cited above, initial research has found that CBD has the potential to help manage the symptoms of anxiety in a variety of cases.

There is also clinical evidence to suggest that CBD can be a tool for managing panic attacks. Panic disorder (PD) impacts about five percent of the total global population, making the anxiolytic effects of CBD products potentially impactful on a widespread level.

There is even clinical evidence that CBD may help minimize the symptoms of obsessive compulsive disorder (OCD), a nervous condition that can be debilitating. Currently, OCD is treated primarily through cognitive behavioral therapy and antidepressants, but the recovery rate is exceedingly low. The prospect of CBD as an alternative intervention is potentially game-changing.

But how exactly does CBD impact those with anxiety conditions? The short answer is that products from the cannabis plant tend to have a strong, reactive effect with the endocannabinoid system, a molecular system that regulates many core functions of the body, including emotions. Cannabinoids can bind to receptors in the endocannabinoid system and modify the way they function, yielding a range of possible health benefits.

In fact, one study notes that “modulating the activity of the endocannabinoid system turned out to hold therapeutic promise in a wide range of disparate diseases and pathological conditions, ranging from mood and anxiety disorders, movement disorders such as Parkinson’s and Huntington’s disease, neuropathic pain, multiple sclerosis and spinal cord injury, to cancer, atherosclerosis, myocardial infarction, stroke, hypertension, glaucoma, obesity/metabolic syndrome, and osteoporosis, to name just a few.”

While CBD may potentially help to manage stress and anxiety, it is not intended as a cure for anxiety or depression.

How to Choose CBD Oil for You

When you’re looking for the best CBD for depression and anxiety, it’s important to choose a product that is safe, effective, and natural. Here are some important things to keep in mind when shopping for CBD.

What to Look For

Always look for the following pieces of information when comparing CBD oils for anxiety: type of CBD, hemp source, strength, and lab testing. Below are more details on what each of these mean and why they matter.

Type of CBD

There are actually three different types of CBD extract, including full spectrum, broad spectrum, and CBD isolate. We typically recommend full spectrum products as the most effective, as they allow you to benefit from the full entourage effect of the hemp extract. However, if you undergo drug testing for work or are sensitive to THC, broad spectrum products offer many of the same benefits without the THC. This can also be important for those who find that THC negatively impacts their anxiety.

Hemp Source

The quality of the CBD is directly related to the source of the hemp used in a product. Always look for brands that use hemp grown in the U.S.A. We also recommend brands that use either USDA organic hemp or hemp grown using organic farming practices. This ensures that the plants do not contain any pesticides and or artificial fertilizers.


It’s important to know the concentration of CBD in a product so that you can take the appropriate dosage level. For those new to CBD, it’s generally recommended to start with a lower dose, 10 mg or less, and slowly increase the amount as you are comfortable to find the right level of relief. Extra strength products, with 30 mg or more per serving, are recommended for those who know how CBD will affect them. You can read more about the strongest CBD oils here.

Lab Testing

Only purchase CBD oils for anxiety that undergo independent third-party lab testing for quality and safety. This is critical to ensure that the product contains the correct levels of CBD and cannabinoids, and that it is free from toxins, heavy metals, or other harmful substances. The brands we recommend all make their lab test results available through QR codes on the product label or on their site.

How to Read Labels

When you check the label of any CBD product, look for information on the four key factors listed above. Labels should clearly state the type of CBD and if it was made with U.S. grown hemp. To evaluate the strength of the product, look for both the amount of CBD per bottle, usually in milligrams per 30 mL, as well as the amount of CBD per serving, usually in milligrams per 1 mL dropper.

Quality products should also include lab-testing certification and a way for you to verify the results for yourself. You can also look for industry certifications and seals from the USDA, Leaping Bunny, the GMO Project, and the U.S. Hemp Authority. Finally, take time to check the list of ingredients to make sure that you are not allergic to any of them. Most CBD oils use a carrier oil like hemp seed oil, olive oil, or MCT coconut oil.

How to Use

For most CBD oils, take a dose once or twice per day, depending on the amount. Some oils work better for daytime use and can be taken in the morning, while others are better suited for nighttime use to help you fall asleep. Again, if you are new to CBD, start with a low amount and slowly increase it to find the correct level to provide relief.

The amount of CBD needed may vary from person to person based on their level of anxiety and other health concerns. One thing that holds true across the board is that using CBD consistently is best for improving stress levels, as the compound builds up within the body, amplifying its effect. In other words, CBD may help you manage anxiety symptoms, but don’t expect it to take effect immediately.

Safety & Side Effects

According to the Mayo Clinic, CBD is generally well-tolerated. There are, however, some mild side effects that can occur. These often result from taking too much CBD, and can include:

  • Dry mouth
  • Diarrhea
  • Reduced appetite
  • Drowsiness
  • Fatigue

Additionally, CBD can potentially interact with certain prescription medications, like blood thinners and certain forms of statins. Always check with your doctor if you plan to start using CBD alongside any prescription medications. No CBD product has been approved by the FDA to treat anxiety or depression, so be sure to do your own research on any product you choose to purchase.

Alternative Options

While CBD may be a great option to help supplement your anxiety management, it is not meant to cure or treat anxiety. If you are suffering from severe anxiety and depression, the best thing to do is speak with your primary care physician or a mental health professional. They may recommend things like cognitive behavioral therapy, journaling, exercise, yoga, or prescription medications to help.

If approved by your doctor, CBD for depression and anxiety may work with these other approaches to help you find relief and better manage stress.

Josh Hurst is a journalist, critic, copywriter, and essayist. He lives in Knoxville, TN, with his wife and three sons. As a writer and independent reviewer of CBD products, Josh covers the relationship between cannabis-based products and the human body. His writing has appeared in Health, Shape, and Remedy Review.

Medically Reviewed By:

Alan Carter
PharmD Scientific Advisor, Medical Reviewer, and Clinical Pharmacist
Adjunct Faculty, UMKC School of Pharmacy