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Cbd oil dosage for narcolepsy

A guide to using CBD oil for insomnia and sleep disorders

Not everyone has the luxury of enjoying uninterrupted sleep. For example, an estimated 50 million Americans suffer from sleeping disorders, which make their day-to-day lives difficult. Fortunately, CBD oil is a proven, effective remedy for insomnia and other sleeping disorders.

Before we get to the sleep disorder medications, let’s look at different types of sleep disorders.

Types of Sleep Disorders


This is, perhaps, the most recognized type of sleeping disorder. Insomnia presents itself as a struggle to fall or stay asleep. Someone might either be suffering from transient or chronic insomnia. Transient insomnia, also known as short term insomnia, is often triggered by certain occurrences happening in our lives, such as stress or jet lag. The chronic kind is when the symptoms of sleep deficiency surpass 30 days with no sign of subsiding.

Sleep Apnea

A person with this sleeping disorder suffers from symptoms of suddenly waking up and gasping for air. What many people may consider a nightmare could very well be sleep apnea. The desperate gasping of air happens due to the patients’ airway closing without warning and restricting airflow. More mild symptoms include heavy snoring and difficulty in breathing.


This is, perhaps, one of the most dangerous kinds of sleeping disorders, where someone suddenly falls asleep without warning. They would fall into slumber as they walk, eat, run, or even while they cook. The danger is that you never know when it might happen.

Restless Leg Syndrome

This sleep disorder occurs when your limbs, mainly your feet, shake uncontrollably, thus preventing you from sleeping. This urge is sometimes accompanied by tingling, aching, or a burning sensation in your feet.


This is not one set disorder but a group of several diseases under the same class, causing abnormal behaviors and movements while you sleep. They include sleepwalking, groaning, talking, nightmares, bed-wetting, and teeth grinding.

CBD and Narcolepsy: An Effective Treatment Option?

Sleep is obviously an essential part of everyone’s life and can have a significant impact on your quality of life. Any interruptions, health concerns, or issues related to your sleeping patterns can create serious worry about your overall well-being. Narcolepsy is an extreme example of something that can affect your sleeping patterns. Studies show that 1 in 2,000 people suffer from narcolepsy and complain about not getting the benefits of sleeping that others do. Keeping this in mind, more people are seeking natural solutions to help alleviate their fatigue and other symptoms. CBD is a natural solution that’s growing in popularity. But what is the relationship between CBD and narcolepsy?

People are looking for simple solutions and supplements that don’t have too many extra chemicals. This is why CBD products have started becoming popular among those dealing with this condition. For those who want to use a natural solution, CBD might be useful. Here is a deeper dive into what makes it a unique option.

Defining Narcolepsy

To better understand what this condition is all about and how CBD products may be helpful, it’s imperative to analyze what the disorder entails and why it can have a major impact on a person’s quality of life.

Narcolepsy is a neurological disorder which impacts a person’s ability to regulate their sleep cycles. For example, an individual with narcolepsy may suddenly feel tired in the middle of the day. This can happen at any time of the day and it can be quite difficult to regulate. It can even occur when the individual has taken the time to sleep for 8-10 hours during the night. These attacks can have a disturbing impact on a person’s quality of life and make it difficult to function and stay healthy.

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It’s important to note, narcolepsy is an umbrella term that describes a disorder that comes in two distinct types. (Type 1, with cataplexy, and type 2, without cataplexy). For reference, the Mayo Clinic defines cataplexy as a sudden, uncontrollable loss of muscle tone. It may be triggered by intense positive or negative emotions. If you have type 2 narcolepsy, you may only experience one or two cataplexy episodes in a year. But you could experience several daily episodes. Each person’s experience is unique.

Understanding the Symptoms of Narcolepsy

CBD has the potential to reprogram your body in subtle yet effective ways that can be sustained long term. This is one of the main reasons CBD products are heralded by the masses as effecting symptoms of many different conditions. For those who are trying to understand how narcolepsy works and what the symptoms are, here is a deeper dive.

Daytime Fatigue/Lethargy

This is the most common symptom an individual is going to have when it comes to dealing with narcolepsy. Essentially the individual is going to feel like they haven’t slept during the night and are starting the next day without any rest at all. This can have a serious impact on a person’s ability to go about their daily activities. It can also lead to additional symptoms such as memory lapses, mental fog, and mood swings.

How Does CBD Help? – CBD may promote the stabilization of energy in the human body, which may then result in consistent sleep patterns, reduced irritability, and the elimination of sudden physical episodes (i.e. muscle weakness).


One of the main symptoms that can lead to accidents involves cataplexy. Cataplexy is when a person loses muscular control and seems to get weak to the point they are unable to regulate how they move. This can cause issues such as total body collapse, slurred speech, and sudden loss of consciousness. Studies show 30-50% of all sufferers end up getting hurt because this symptom comes on suddenly.

How Does CBD Help? – CBD may regulate the production of hypocretin (orexin) in the human body. This plays a role in sudden muscle weakness that can even stem from fluctuations in emotion (i.e. stress/laughter).


Some people will mention starting to see or hear things that aren’t present in real life. The brain can cause these hallucinations in an effort to convince you to get some sleep as soon as possible.

How Does CBD Help? – Studies involving patients with episodes of hallucinations have demonstrated a noticeable effect using CBD [3]. This includes reducing the flaring of specific receptors in the brain that cause hallucinations and/or psychosis.

Sleep Paralysis

In rare cases, some individuals cite sleep paralysis as a symptom of their condition. This means they are unable to move/speak when they wake up. This usually doesn’t last for a long time (a few seconds or minutes) but is something that can have a profound impact on a person’s psychological well-being.

How Does CBD Help? – Sleep paralysis may be restricted through CBD use by increasing the central nervous system’s response time during the REM cycle. Thus, when an individual wakes up, they are not left in a state of immobility.

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Understanding the Causes of Narcolepsy

Treating narcolepsy requires a good understanding of the underlying symptoms. The reason CBD is noted as being a potential tool for managing narcolepsy comes down to the root causes of this condition. By understanding these causes, it becomes easier to realize the importance of the relationship between CBD and narcolepsy. So what are the main causes of narcolepsy?


In general, narcolepsy can be triggered by certain factors throughout a person’s life. For example, this could be something as simple as going through a stressful break up with your partner and finding it difficult to overcome. This sort of traumatic experience can develop into an onset of narcolepsy.

How Does CBD Help? – High cortisol levels can elevate a person’s stress and cause the endocannabinoid system to malfunction. This leads to significant symptoms such as fatigue, anxiety, and other related symptoms. CBD helps regulate the body’s cortisol levels and keeps them within a manageable range.

Rapid Fluctuations in Emotions

In the same vein, there are additional triggers that can do the same thing. Extreme excitement at the birth of a child or dealing with death in the family can both be very emotional events. Though these events may lead to different types of emotions, they can both trigger narcolepsy symptoms.

How Does CBD Help? – CBD may act as a relaxant to ease a person’s emotional triggers and thus soothes the body too. This may help limit an individual’s likelihood to drastically fluctuate between emotions (i.e. elation, depression) .

Genetic Predisposition

On the other hand, other causes are inherent according to medical professionals. For example, some individuals are going to be born with a specific genetic code that causes them to be predisposed to narcoleptic episodes.

This has to do with chromosome 12 in the human body and it directly affects your ability to sleep. If something is off in this regard, you are more likely to have a longer-term battle against narcoleptic episodes.

How Does CBD Help? – While CBD cannot change an individual’s DNA, it can offer respite from the resulting symptoms (i.e. stress, fatigue, and a malfunctioning endocannabinoid system). This should improve a person’s quality of life.

In most cases, a person won’t deal with gene-related issues when it comes to narcolepsy and it will only play a role in your life based on the triggers mentioned above. However, it’s best to stay informed and aware of all possible causes.

Final Thoughts on CBD and Narcolepsy

Since CBD products (from the right source) are 100% organic, this makes it easier for individuals to use them without hesitation. Pharmaceutical medications can have dangerous side effects and may not be worth taking because of the impact they can have on your health. CBD is a straightforward supplement that may help control symptoms associated with narcolepsy. It is easy to use and has many other potential benefits for your body and mind.

Individuals that use CBD products claim to notice a change in how they sleep and how they feel when it comes to symptoms such as cataplexy. They feel more in tune with themselves throughout the day and don’t lose as much control of their limbs. Whether this has to do with hallucinations, daytime sleepiness, and/or fatigue, there is nothing worse than feeling like you are not in control of your body.

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If you are living with narcolepsy and its related symptoms, feel free to browse Tanasi’s wide range of high quality CBD products. This is a world-class CBD provider with millions of dollars of research behind it. They can deliver 100% natural CBD straight to your front door.

Cannabidiol Partially Blocks the Excessive Sleepiness in Hypocretindeficient Rats: Preliminary Data

Background: Excessive daytime sleepiness and cataplexy are among the symptoms of narcolepsy, a sleep disorder caused by the loss of hypocretin/orexin (HCRT/OX) neurons placed into the Hypothalamus (LH). Several treatments for managing narcolepsy include diverse drugs to induce alertness, such as antidepressants, amphetamine, or modafinil, etc. Recent evidence has shown that cannabidiol (CBD), a non-psychotropic derived from Cannabis sativa, shows positive therapeutic effects in neurodegenerative disorders, including Parkinson´s disease. Furthermore, CBD provokes alertness and enhances wake-related neurochemicals in laboratory animals. Thus, it is plausible to hypothesize that excessive somnolence observed in narcolepsy might be blocked by CBD.

Objective: Here, we determined whether the systemic injection of CBD (5mg/kg, i.p.) would block the excessive sleepiness in a narcoleptic model.

Methods: To test this idea, the neurotoxin hypocretin-2-saporin (HCRT2/SAP) was bilaterally injected into the LH of rats to eliminate HCRT leading to the establishment of narcoleptic-like behavior. Since excessive somnolence in HCRT2/SAP lesioned rats has been observed during the lights-off period, CBD was administered at the beginning of the dark phase.

Results: Hourly analysis of sleep data showed that CBD blocked the sleepiness during the lights-off period across 7h post-injection in lesioned rats.

Conclusion: Taking together, these preliminary findings suggest that CBD might prevent sleepiness in narcolepsy.

Keywords: Cannabidiol; hypocretin-deficient rats; lateral hypothalamus; narcolepsy; neurodegenerative disorder; rapid eye movement sleep..

Copyright© Bentham Science Publishers; For any queries, please email at [email protected]

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