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Cbd oil suppositories for cancer

Rectal Cannabis Suppositories

Despite the fact many people start to giggle when someone mentions rectal suppositories, this way of application is not funny and has many advantages. Suppositories are especially suitable for patients who cannot or don’t want to ingest or inhale cannabis.

Suppositories infused with medicinal cannabinoids have relatively fast onset of action – a bit slower than while you smoke cannabis, but faster than edibles; and its effects last longer. However, the biggest advantage of this way of application is that even if you apply a relatively large dose of psychoactive THC you will not feel as “high” as if you consume the same amount orally (both smoking and eating).

How Do They Look Like?

Cannabis suppositories have usually conic shape and they are administered rectally (vaginal suppositories are specific, and they would deserve a separate article). A two grams suppository (the most common) is approximately 2.5 cm long, and the basic mixture is made from cocoa butter with a “touch” of coconut oil or shea butter – all of that mixed with cannabis extract. If you do not have an access to the extract, you can mix cocoa butter with dried cannabis buds and prepare the basis the same way, as if you were making homemade cannabis cream.

How Do They Work?

Suppositories are an effective way of administering cannabis during the treatment. After they are inserted into rectum, the cannabinoids are quickly absorbed through large intestine wall directly into bloodstream. Process of application is not difficult at all – you can ask your doctor or find instructions on the internet.

In case of smoking, the effects are almost immediate, but they do not last long unless the inhalation is frequently repeated. When eaten, the effects can be felt as late as 30 minutes after consumption because active ingredients have to pass through intestines and liver. To the contrary, the effects of cannabis suppositories are noticeable already after 10–15 minutes and they last from four to eight hours.

Bioavailability (absorbability) of cannabis during smoking is just 10–25 per cent depending upon frequency of smoking and dosing. The efficiency of eating of cannabis products is approximately 20–30 per cent and the effects can vary greatly. On the other hand, the bioavailability of rectal administration is between 50–70 per cent and its effects on individual patients with various diagnoses can be easily predicted.

Who Are They for?

Suppositories are ideal choice for many patients – for example for those undergoing chemotherapy; these people suffer from severe nausea and thus it is often impossible for them to digest cannabis edibles. They are also suitable for elderly and children and for those who cannot swallow pills. Moreover, suppositories would benefit surgical patients who cannot eat immediately before and after operations, and also patients who are unable to swallow due to stroke or another disease.

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Concerning specific indications, suppositories are suitable for patients with Crohn’s disease, ulcerative colitis, and other diseases associated with a gastrointestinal tract and excretion. Many male patients also report that suppositories are effective especially in treating various health problems associated with prostate.

However, we should note that there has not been much of scientific research in this method of cannabinoids application.

How to Use Them?

Suppository forms are usually sold in two-gram version for adults and one-gram version for children. When they are prepared, they should be stored in a cold place. Before inserting, it is good to make sure that the suppository is firm. If not, put it into a fridge or a freezer (it is actually best to store them in fridge the whole time).

Lie sidelong and crouch. Using your index finger, insert the suppository into your rectum, pointed end first. Insert it circa 2.5–4 cm deep, all the way behind the inner anal sphincter.

To prevent the suppository from slipping out, you must clench your buttocks together firmly and flex muscles of your anal sphincter for 2–3 seconds.

Keep lying sidelong at least for next few minutes. There is a risk that fluid from the suppository will mildly leak during next few hours – you should take that into account when planning other activities (this is why the best time to apply the suppository is before you go to sleep).

What Can You Expect?

You will probably feel warm feeling spreading from the area of your pelvis to the rest of your body. It should pretty quickly alleviate your pain (of course it depends on the particular cannabinoid content) and the effects should last up to 5–6 hours, and at the same time you should not be feeling anxious or “high”. Most of the patients are delighted by the effects of suppositories when they compare them to other ways of application of cannabis.

Preparation:

The time-tested mixture contains 75–80 per cent of cocoa butter and 10 per cent of coconut oil and shea butter. Shea butter and coconut oil have tendency to melt already around 25 degrees of Celsius – that is the reason why they should not be put into the basic mixture in bigger amounts.

You can order moulds for suppositories in various e-shops with medical supplies (they can be also rarely found in pharmacies). Volume of these moulds should be one or two millilitres / grams.

To start making your suppositories you also need last important thing – a cannabis extract (in case you cannot obtain it proceed the same way as if you were making cannabis cream with dried buds).

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Example of dosing: to make one set (10 pieces) of one-gram suppositories containing 10 per cent of cannabis extract, warm 9 millilitres of basic mixture with 1 millilitre of extract in water bath until the extract completely dissolves. Mould for the suppositories should be then fixed into a holder. Let the mixture cool for a while and then pour into moulds of all 10 suppositories.

Product Feature: THC Suppositories

Product Feature: THC Suppositories 2019-08-30 2020-10-28 https://ceresmedvt.com/wp-content/uploads/2021/05/ceres-med-logo-m.png CeresMED https://ceresmedvt.com/wp-content/uploads/2019/08/suppositories_web-e1567185537831.jpg 200px 200px

THC Suppositories can offer a variety of unique benefits for medical cannabis patients, but are generally underused due to a lack of familiarity (and sometimes comfort) with the application method. Suppositories have been used medicinally for centuries, and herbalists and naturopaths often recommend them due to the high level of bioavailability of the active ingredients. The term “suppository” generally refers to a medicine that is inserted rectally, but may refer to vaginal medicines as well. Suppositories are usually well-tolerated with minimal side effects.

Why are THC Suppositories Effective?

Suppositories can be effective for systemic pain and inflammation relief. There are numerous cannabinoid receptors in the GI tract to which cannabinoids can bind, rapidly absorbing through the GI lining into soft tissues and the bloodstream. In general, suppositories have a faster onset, higher bioavailability, shorter peak and shorter duration than oral administration. It is estimated that suppositories result in about 80% bioavailability, compared with 35% for oral administration. This is largely due to the fact that suppositories bypass roughly two thirds of first-pass metabolism that occurs during digestion.

Benefits of THC Suppositories

Suppositories can be ideal for patients that don’t want to experience the intoxicating effects of THC. The cannabis contained within are absorbed directly into the bloodstream and distributed through the vascular system, bypassing the liver altogether. The liver converts THC to the more potent and sedative compound 11-hydroxy-THC. When cannabis is smoked or digested, the THC passes through the liver before it reaches the brain.

While THC suppositories can be therapeutic for a wide variety of different health concerns, patients report that they are particularly effective for symptoms related to Crohn’s disease, IBS, prostate cancer and multiple sclerosis (MS). Suppositories are also commonly used by patients who experience nausea as a result of chemotherapy or underlying illnesses, and are unable to consume cannabis edibles. They can be an excellent alternative to edibles as a sleep aid, as they contain no sugar and are ideally used just before bedtime.

Vaginal Suppositories

Vaginal suppositories that contain THC are typically lower potency because of the extreme sensitivity of vaginal membranes. They are reported to reduce menstrual cramps within 20 minutes (they can be used with tampons), and may also be effective for managing the symptoms of cervical cancer, endometriosis, adenomyosis and pelvic floor dysfunctions. Vaginal suppositories should be made with the correct pH to avoid negative side effects like yeast infections. The suppositories we carry are made with either coconut oil or cocoa butter. Coconut oil is naturally slightly acidic with a pH of 5-6, and cocoa butter has a pH of 5-5.6. A healthy vaginal pH is also slightly acidic, between 3.8 and 4.5 – caution should be used for those who are highly sensitive to changes in pH.

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Tips for Taking Advantage of the Benefits of Suppositories

While suppositories are simple to use, there are a few key things to know about them:

• Suppositories must be kept refrigerated or frozen until immediately before use because they soften rapidly at room temperature.

• Ensure good hygiene by washing hands before and after use.

• To get the full benefits, suppositories should remain within the body until they have fully absorbed.

• To ensure they remain within the body, suppositories should be used just before bedtime.

• When applied rectally, insert past the sphincter muscle and wait 15-20 minutes before a bowel movement to allow the CBD to take effect.

• Vaginal insertion is best done in a reclining position to allow the suppository to be easily placed high in the vagina.

The following options are available at CVD/SVW and Ceres Natural Remedies.

  • 2:1 CBD to THC (Available at CVD/SVW) Made with Indica-dominant cannabis extract, 22mg CBD + 10mg THC, cocoa butter, and coconut oil.
  • THC (Available at CVD/SVW) Made with 17.5mg Hybrid cannabis extract, cocoa butter, and coconut oil.
  • CBD (Available at Ceres Natural Remedies – no medical card needed for purchase) 50mg and 100mg CBD options.

“Women with adenomyosis, endometriosis, and heavy, painful periods often use hormonal birth control, ibuprofen, and opioids to manage pain. The side effects from these treatments can be harmful to your system. CBD and cannabis vaginal suppositories offer a safe, holistic alternative and have given both myself and my clients immediate relief from pelvic pain and menstrual cramps.” – Sara Lopez.

Sara is a Certified Hormone Specialist + Women’s Health Coach with a specialty in adenomyosis, endometriosis and heavy periods. She works with women all over the world to improve their worst symptoms holistically so they can truly thrive. Sara is the founder of Gush Online magazine gushbeauties.com, a digital platform for brave beauties with adenomyosis, endo, & heavy periods. You can follow her on Instagram at @transformadeno.