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CBD and Erectile Dysfunction: Does CBD Help Improve Sex Life?

Erectile dysfunction (ED) affects millions of Americans every year. But like many conditions affecting people every day, cannabidiol (CBD) may offer a solution – but there’s a significant emphasis on “may.”

Realistically, we don’t know how to use CBD or cannabis plant extract for erectile dysfunction. There are a lot of questions to answer before we know if CBD oil can help.

But it’s not all doom and gloom. The indirect evidence provides some clues on how to use CBD oil for erectile dysfunction or the role of the endocannabinoid system.

If you’re looking for help without conventional medication, it doesn’t hurt to see what CBD can do to help with libido, ED, sexual performance, sexual pleasure, and more.

How does CBD Affect Libido?

We don’t have much data on how CBD affects libido – if at all. So far, studies have shown mixed results supporting and doubting whether CBD can improve your sex drive.

For instance, a 2015 study by du Plessis et al. noted that heavy cannabis use among males led to an increased chance of ED. However, THC is a factor, making it difficult to determine if CBD, THC, or other compounds in cannabis are responsible for those adverse effects.

At the same time, a 2018 review in the Journal of Affective Disorders noted how CBD might have a calming effect, potentially reducing things – like performance anxiety – that hamper sex drive. We’ll get into a lot more detail on that later.

Does CBD Make You Last Longer in Bed?

CBD may help you last longer in bed – at least according to many anecdotal claims. There’s also no feasible way to collect that kind of data in a controlled lab setting. Theoretically, peer-reviewed research would rely on self-reporting.

CBD Oil for Erectile Dysfunction

Unfortunately, no peer-reviewed studies specifically focused on CBD oil as a potential treatment for erectile dysfunction. However, erectile dysfunction isn’t an isolated condition. Instead, it’s a consequence of other underlying issues, both physical and mental.

Early evidence suggests CBD oil can help mitigate some physical and psychological factors known to cause erectile dysfunction. We’ll cover those later.

What Research Says about CBD and ED

We all know that endocannabinoid (ECS) receptors exist in the central nervous system (CB1) and many areas of the body, including the immune system (CB2). However, a 2009 article from Annals of the New York Academy of Sciences found CB1 receptors in the testes of lab rats.

This discovery is incredibly relevant because CB1 receptors are primarily found in the central nervous system, whereas the peripheral areas mostly contain CB2.

So what does this mean for erectile dysfunction? It proves that the ECS’s reach extends to the reproductive system in rodents. If the same is true for humans, it may be possible to use CBD oil for erectile dysfunction.

According to a 2014 study published in Biomed International, cannabis has a long history as a sexual aid. People who follow the Ayurveda lifestyle – an ancient Hindu health approach involving herbal remedies, yoga breathing, and strict diet – claim the plant helps improve ejaculatory function and performance.

However, there’s no hard evidence to support these anecdotes.

A 2017 study in JCI Insight revealed CBD’s potential to help with blood pressure. However, it focused on arteries to the heart, not the reproductive system. Consequently, we can only infer from this existing research whether CBD oil can help with ED.

But if the same mechanism works with erectile dysfunction, CBD oil could help dilate reproductive blood vessels and increase blood flow to the penis. This effect may improve sexual function.

Does CBD Oil Increase Testosterone?

Research isn’t conclusive – at least not yet – but what we have so far doesn’t indicate a connection between CBD and increased testosterone.

A 2009 study published in the Journal of Toxicology and Environmental Health tested the effects of several cannabinoids on hormones in monkey and rat test subjects. Admittedly, it was heavily THC-focused. However, testosterone levels in monkeys remained unchanged. Rodents showed a decrease in testosterone levels at very high – and impractical – doses.

A 2019 review in the Journal of Applied Toxicology revealed more bad news. The article analyzed over 30 pieces of existing literature covering studies on men, rodents, monkeys, and invertebrates. The publication says CBD shrunk mammalian testes, impaired fertility, and reduced general blood hormone concentration.

They further say:

“Moreover, chronic doses of CBD have impaired sexual behavior in mice. From the studies identified in this review, it is possible to conclude that CBD has negative effects on the reproductive system of males.”

But the authors also say research is limited, calling for a deeper look at CBD’s potential benefits and risks to the male reproductive system.

Overall, those studies don’t indicate that CBD can increase testosterone – at least not directly, anyway.

But what about indirect routes? Could some of CBD’s benefits help increase or balance testosterone?

This brings us back to some information and studies we covered earlier. Specifically, CBD’s potential benefits against things that affect testosterone production – like anxiety and high blood pressure (hypertension) – can make a difference.

Overall, it’s best to proceed with caution before using cannabis or CBD for the treatment of any condition. With luck, the research could one day shed more light on the subject, but we’re a far cry from FDA-approved CBD treatments for hormonal deficiencies.

What Causes Erectile Dysfunction?

There are many causes of erectile dysfunction (ED), ranging from temporary problems to chronic health conditions. Furthermore, erectile dysfunction can be a symptom of something else, making it more than just a roadblock to your sex life.

Physical Causes of ED

The Urology Care Foundation provides an extensive list of physical reasons for why you may experience ED. Below are some common causes:

  • High blood pressure
  • Diabetes
  • Impaired blood flow to the penis
  • High cholesterol
  • Heart disease
  • Prostate issues
  • Injuries to the spine or pelvic area
  • Medicinal side effects
  • Hormone imbalance

Psychological Causes of ED

You may feel healthy, but sometimes the root of sexual dysfunction lies beyond the physical causes of ED. According to the Urology Care Foundation, several emotional factors can contribute to ED.

  • Performance anxiety
  • Anxiety disorders
  • Depression
  • Stress from work, friends, or family
  • Guilt or shame
  • Relationship problems

Lifestyle Causes of ED

While we can’t control some of the things that trigger erectile dysfunction, there are many ways we can actively reduce the chance of ED affecting sexual performance.

  • Obesity
  • Tobacco use
  • Drugs and alcohol
  • Lack of exercise

How CBD May Help with Erectile Dysfunction

How can CBD oil help with erectile dysfunction? Based on what we see so far, the answer lies in treating some of the underlying issues responsible for ED.

Anxiety and Depression

Sexual health and mental health are intertwined. Even if you don’t have a chronic issue like anxiety or depression, those states of mind can still trigger erectile dysfunction.

A 2018 review in the Journal of Affective Disorders examined cannabis’ impact on depression, stress, and anxiety. Based on the research, CBD oil could reduce anxiety and depression for some individuals.

Keep in mind THC was a factor, making it difficult to determine which (if any) cannabinoid was responsible for the therapeutic effects.

Hormone Imbalance

Hormone imbalance can also lead to ED. But while a natural supplement like CBD may not – at least according to current research – impact testosterone, hemp-derived CBD may still impact other hormones.

According to a 2006 study from Endocrine Reviews, the endocannabinoid system and endocrine system are closely linked, so much so that CBD could alter hormones meant to reach other glands. This helps contribute to the body’s equilibrium or “homeostasis.”

Although theoretically promising, nobody has explored this connection’s impact on erectile dysfunction.

Links to Diabetes

Erectile dysfunction isn’t just a source of anxiety, stress, and depression that disrupts your sex life. Sometimes, it’s a sign of something more sinister.

According to the Centers for Disease Control (CDC), 34.2 million Americans have diabetes (1 in 10), while a staggering 88 million (1 in 3) are on the cusp of developing the condition (prediabetes).

We don’t recommend foregoing conventional treatment for diabetes because the research into CBD isn’t solid enough to take such a risk. However, a 2012 study in Obesity discovered that the ECS might play a role in blood sure regulation and insulin activity.

Although the research focused more on the endocannabinoid 2-AG and the ECS as a whole, they noticed that obese individuals have higher endocannabinoid levels. The authors theorized:

“Thus, the increased endocannabinoid levels observed in human obesity may constitute an initial compensatory mechanism to improve insulin function and to overcome insulin resistance associated with obesity.”

In plain English, this means the higher endocannabinoid presence for obese patients could be the first line of defense against insulin resistance and irregular blood sugar levels.

Links to Atherosclerosis

Atherosclerosis refers to the buildup of fatty plaque that blocks arteries and shrinks blood vessels. This condition reduces blood flow and – in time – potentially leads to life-threatening health complications.

“The potential ability of CBD treatment in humans to reduce the cardiovascular (as well as behavioral) response to stress could have significant effects on the development of atherosclerosis and hypertension [high blood pressure], which are known to be accelerated by stress.”

In other words, CBD’s possible two-pronged approach to cardiovascular and mental health may help reduce the chance of developing or exacerbating atherosclerosis.

Is It Worth Trying CBD for ED?

Yes, it is worth trying CBD for ED, just like it’s worth trying for any other symptoms or just as a nutritional supplement.

While studies so far show CBD may not help increase testosterone levels, many of its other reported benefits might help mitigate some of the mental and physical factors that lead to erectile dysfunction.

There’s promising evidence that CBD products can address many of the issues above, thanks to their relationship with the endocannabinoid system.

CBD Products to Try for Erectile Dysfunction

Although the Food and Drug Administration hasn’t examined cannabidiol for erectile dysfunction, CBD products are still widely available for you to try.

CBD Oils

CBD oils are pretty self-explanatory. You ingest a pre-measured dose and wait for the effects. However, due to the delay of 15 to 45 minutes, it’s not a viable option for instant results.

On the other hand, regular daily doses could help keep things like anxiety, depression, stress, and other ED-related health issues in check.

CBD Topicals

Many people use CBD creams for their possible anti-inflammatory and analgesic effects. However, there are other products besides simple creams and balms.

Some vendors offer sexual lubricants made with hemp-derived CBD. There’s no research about the effectiveness of these products, but anecdotal evidence suggests it helps increase sexual pleasure and improve sex life.

CBD Vapes

Vaping or smoking carries the advantage of virtually instant effects. However, we know nothing about how vaping CBD can directly impact ED. But again, cannabidiol’s other alleged health benefits can quickly address some of the underlying factors, like stress and performance anxiety.

How do I Use CBD Oil for Erectile Dysfunction?

To use CBD oil for erectile dysfunction (or anything else), you first need to discuss it with a doctor. If you get the go-ahead, gradually titrate the dose per the manufacturer’s instructions.

If you need help figuring out your ideal dose, Colorado Botanicals offers an excellent beginner’s guide that addresses everything you need to know as a new CBD user.

When to Take CBD?

When to take CBD depends on your needs. Some consume their dose in the morning, the evening, or split throughout the day. There’s no established rule, so experiment to see what works for you.

However, if you choose vaping or topicals, your CBD consumption will vary on an as-needed basis due to the instant effects. For instance, you might vape CBD when hit with a sudden case of performance anxiety.

How Long for CBD Oil to Take Effect?

CBD oil typically takes effect in 15 to 45 minutes.

Is it Safe to Take CBD?

It’s safe to take CBD oil in most cases. However, some people experience minor side effects that typically go away fast.

However, if you take any prescription medications, we recommend avoiding ingestible CBD products without medical supervision.

The Bottom Line: Does CBD Improve Sex Life?

There’s no denying that the cannabis plant has enormous potential, but a lack of evidence makes it difficult to learn how to use CBD oil for erectile dysfunction. But if you think CBD will instantly cure sexual dysfunction, erectile or otherwise, we’re sad to say the evidence so far doesn’t support that.

Still, CBD’s more established (but still unconfirmed) benefits can address many of the underlying problems that contribute to ED.

From mental health issues like stress, anxiety, and depression; to injuries or poor health habits, CBD could ease those contributing factors and improve your sex life.

However, the Food and Drug Administration isn’t eager to get behind cannabidiol. And not to sound like a broken record, but we need much more research to see how CBD oil can help – if at all.

Considering the ambiguity behind CBD’s relation to erectile dysfunction (if any), it’s best not to get too excited. Don’t start using CBD or any supplement without first taking medical advice from a doctor or other licensed health professional.


Carvalho, Renata K., et al. “The Effects of Cannabidiol on Male Reproductive System: A Literature Review.” Journal of Applied Toxicology, vol. 40, no. 1, 17 July 2019, pp. 132–150, 10.1002/jat.3831. Accessed 9 Nov. 2021.

“National Diabetes Statistics Report, 2020.” Centers for Disease Control and Prevention, 11 Feb. 2020, Accessed 10 Nov. 2021.

Chauhan, Nagendra Singh, et al. “A Review on Plants Used for Improvement of Sexual Performance and Virility.” BioMed Research International, vol. 2014, 2014,, 10.1155/2014/868062. Accessed 9 Nov. 2020.

Cuttler, Carrie, et al. “A Naturalistic Examination of the Perceived Effects of Cannabis on Negative Affect.” Journal of Affective Disorders, vol. 235, Aug. 2018, pp. 198–205,, 10.1016/j.jad.2018.04.054. Accessed 10 Nov. 2021.

du Plessis, Stefan S., et al. “Marijuana, Phytocannabinoids, the Endocannabinoid System, and Male Fertility.” Journal of Assisted Reproduction and Genetics, vol. 32, no. 11, 16 Aug. 2015, pp. 1575–1588,, 10.1007/s10815-015-0553-8. Accessed 29 Jan. 2020.

“Erectile Dysfunction (ED): Symptoms, Diagnosis & Treatment – Urology Care Foundation.”, Accessed 8 Nov. 2021.

Fasano, Silvia, et al. “The Endocannabinoid System: An Ancient Signaling Involved in the Control of Male Fertility.” Annals of the New York Academy of Sciences, vol. 1163, no. 1, Apr. 2009, pp. 112–124,, 10.1111/j.1749-6632.2009.04437.x. Accessed 10 Nov. 2021.

Motaghedi, Roja, and Timothy E. McGraw. “The CB1 Endocannabinoid System Modulates Adipocyte Insulin Sensitivity.” Obesity, vol. 16, no. 8, Aug. 2008, pp. 1727–1734, 10.1038/oby.2008.309. Accessed 10 Nov. 2021.

Pagotto, Uberto, et al. “The Emerging Role of the Endocannabinoid System in Endocrine Regulation and Energy Balance.” Endocrine Reviews, vol. 27, no. 1, Feb. 2006, pp. 73–100, 10.1210/er.2005-0009. Accessed 10 Nov. 2021.

Rosenkrantz, Harris, and Henry J. Esber. “Cannabinoid‐Induced Hormone Changes in Monkeys and Rats.” Journal of Toxicology and Environmental Health, vol. 6, no. 2, Mar. 1980, pp. 297–313, 10.1080/15287398009529853. Accessed 10 Nov. 2021.

Stanley, Christopher P., et al. “Is the Cardiovascular System a Therapeutic Target for Cannabidiol?” British Journal of Clinical Pharmacology, vol. 75, no. 2, 10 Jan. 2013, pp. 313–322, 10.1111/j.1365-2125.2012.04351.x. Accessed 10 Nov. 2021.

How to use CBD oil for erectile dysfunction?

Erectile dysfunction, ED, in short, is a common sexual problem that affects most men’s mental and physical health. Does the therapeutic properties of CBD oil help in treating ED? How to use CBD oil? Let us discuss.

Undoubtedly, there is an increase in demand, supply, and reputation for CBD products for their extensive application in managing several conditions. But, when it comes to erectile dysfunction, most men feel embarrassed to talk about it. In such a case, can the therapeutic potential of cannabis-based CBD products help treat symptoms of ED? Although we have discussed the multiple therapeutic benefits of cannabinoids, it is indispensable to understand the nature of any disorder so that assessing the remedial role of CBD could be more effective, in this case, erectile dysfunction.

Erectile Dysfunction: Top Health Concern

Several websites, blog posts, and social media references point out that as many as 30 million men from different age groups are affected by ED. Although this may be true, our Hemppedia editorial team wanted to look at data about ED from a different perspective.

Although ED is a common cause of concern in men’s health, not many people know it is treatable.

Did you know that during the forecast period 2019-2025, the global erectile dysfunction drugs (Viagra, Tadalafil, Alpostadil cream, and more) market size is valued at USD 2930 million in 2025? Expected to register a Compound Annual Growth Rate (CAGR) of 3.5%.

These numbers seem more alarming than the incidence of ED. Is the data an outcome of the marketing effect of erectile dysfunction drugs, or does it indicate that more population is susceptible to ED?

When it comes to male health, among the top 10 most concerning conditions, depression, diabetes, and alcohol addiction occupy prominent positions. Although these are comorbidities, they are fundamental factors that lead to erectile dysfunction. Moreover, this condition is often multi-factorial, meaning one or more causes lead to this debilitating situation.

Let us understand further.

What is erectile dysfunction?

The National Institutes of Health Consensus Conference has defined erectile dysfunction (ED) as “a consistent inability to attain or maintain a penile erection, or both, sufficient for adequate sexual relations”.

Some people refer to ED as impotent, but not an often-used term by healthcare professionals.

Types of sexual dysfunction

A 2004 study 1 points out five types of sexual dysfunctions affecting men.

  • Low libido (sexual interest)
  • Erectile dysfunction(ED)
  • Premature ejaculation (reaching orgasm too quickly)
  • Delayed or inhibited orgasm
  • Physical abnormalities of the penis

Although there are correlations between these types, this article aims to discuss ED in detail. Equally important, to analyze the potential benefits of CBD oil for managing symptoms of ED.

Causes of erectile dysfunction

A 2017 study 2 reports that ED is a natural part of aging. Its occurrence increases with age coupled with testosterone (androgen) deficiency. A decrease in testosterone causes a decrease in erections, diminishing the blood supply to the penis. Consequently, the penis fails to create rigid erections. Hence, ED not only affects sex life but also could indicate undiagnosed coronary artery diseases(CAD) and diabetes mellitus.

References from the 2016 ED study 3 and a 2018 study 4 report on the causes of ED. They are presented in a simplified tabular form as given below.


Endocrine factors Non-endocrine factors
Reduced serum testosterone levels Vasculogenic: affecting blood supply, clogged arteries. For eg: Hypertension, high blood pressure, cigarette smoking
Hormonal imbalances, sexual function, reproduction, sleep, mood, anger Neurogenic: abnormalities in neural relations. For eg: spinal cord injury, multiple sclerosis, Parkinson’s disease, lumbar disc disease, traumatic brain injury, etc
Metabolic disorders, poorly controlled Diabetes mellitus Iatrogenic: medical or surgical treatment for a pelvic fracture or pelvic surgery
Tissue disorders Kidney diseases, prostate enlargement, urinary tract infection


Psychogenic factors Confounding factors
Adrenaline mediated ED. Alcohol consumption
Stress, depression, and anxiety together defined as heightened anxiety. Periodontal diseases, oral health
avoidance of sex due to performance anxiety, lack of sexual desire, loss of self-esteem, deteriorated quality of life. Medications used to treat ED, anti-ulcer drugs, opiates, hypertension drugs, tricyclic antidepressants, selective serotonin reuptake inhibitors, benzodiazepines,etc
Psychiatric symptoms, personality disorders, social anxiety disorder and schizophrenia Lack of physical activity leading to hyperlipidemia

Summing up from the above two tables, we have understood that ED is a multifactorial condition. A combination of organic, non-organic, and lifestyle-led factors contribute to the development of the disorder.

More key takeaways from the 2016 ED study 3 :

  • There is a strong correlation between ED and lower urinary tract symptoms (LUTS) in men with mild benign prostatic hyperplasia (BPH) or prostate gland enlargement.
  • Erectile dysfunction generally precedes cardiovascular conditions. Therefore, it can be used as an early indicator to ascertain major cardiovascular problems.
  • Tobacco smoking addictions increase the risk of ED as smoking has a direct impact on ED.

Key takeaways from the 2017 study 5 :

  • Vascular diseases are the most common causes of ED, but the exact pathway is still unknown.
  • There is a link between chronic periodontitis (CP) and ED because both diseases share common risk factors and lead to endothelial dysfunction. Therefore men with mild to severe ED showed a higher prevalence of CP.

(Chronic periodontitis is a common oral cavity disease that causes chronic inflammation of the periodontal tissues and accumulation of dental plaque)

Additionally, research suggests that ED can begin due to an injury to the penis from sports or accident, autoimmune diseases, Peyronie’s disease, medical or family history, etc. These impact sexual health, sexual disorders, or painful sex.

How to treat ED?

There are several treatment options available to treat ED. If you seek timely professional medical advice, you can improve your sex life and overall well-being.

A 2014 study 6 points out that reports of ED date back to 2000 BC.

The 2016 study 3 reports that since the 15th-century, interest in this subject and its remedies have remained constant.

Therefore we can say that modern advanced treatments for ED have drawn inspiration and guidance from conventional remedies.

Let us briefly look at some of the current remedies in practice to treat erectile dysfunction.

  • Oral prescription medications
  • Penile Implantable Devices
  • Surgery ( Artery reconstruction)
  • Injectable medicines & Suppositories
  • Alternative medicines, Dietary supplements, Botanical drugs from plants & herbs

Oral prescription drugs:

Oral drugs such as sildenafil, tadalafil, and vardenafil are PDE5 inhibitors. They help relax penile tissues and stimulate sexual arousal leading to enhanced sexual performance or longer-lasting sex. Phosphodiesterase 5 (PDE5) helps increase blood flow to the penis by relaxing the blood vessels.

From a 2013 study 7 we can understand that PDE5 is an enzyme found in the penis and the clitoris, smooth vascular, bladder and prostate muscles, and platelets.

Research suggests that complete care must be taken into account while treating erectile dysfunction patients. Especially examining their other health problems, history, and psychological examinations, accompanied by constant follow-ups. Because, unlike natural supplements, these prescription drugs do present side effects.

For example, the 2005 study 8 reports that although sildenafil is safe in men with coronary heart disease, and not to be used with nitrates. And side effects include headache, flushing, and dyspepsia.

Implantable devices or prostheses:

Implantable devices or prostheses are physical objects, usually one to a three-piece device.

The device gets placed inside the penis through a surgical procedure. Post recovery from surgery, the patient could control his erection with the help of the implant.

External Devices such as vacuum erection devices help achieve an erection. Here, the penis is inserted through a plastic cylindrical vacuum pipe to pull blood into the penis. An elastic ring is placed at the base of the penis to prevent blood from flowing back to the body.

Artery reconstruction:

The physiological process of erection involves the brain, nervous and vascular systems. The process begins with the brain that sends arousal signals to the penile nerves transmitting the same to the spinal cord and penis to cause an erection. When the nerve impulse reaches the two erection chambers inside the penis(corpora cavernosa), it relaxes the penile tissue, and the blood vessels in the chambers get filled with blood. Subsequently, the penis swell in size traps the blood and makes it hard and erect.

Arterial surgery is a remedy to help erectile function normally by removing blockages in penile chambers and create better blood flow.

A 2013 study 9 reports that penile vascular reconstructive surgery should be a promising option in the near future provided it is handled cautiously with appropriate surgical methods.

Injectable medicines and suppositories:

Injectable medicines trigger automatic erections, unlike oral medications.

For example, Alprostadil is injected into the penis and as a urethral suppository.

Suppositories are pills specially designed for administering certain medications through anal or vaginal cavities. They are generally in a cone or oval shape that contains the medicine.

New advancements in treating ED

The 2014 study 10 elaborately discussed new technological advancements in ED management. Such as external penile support devices, vibrators, low-intensity extracorporeal shockwave, impulse magnetic field therapy, tissue engineering, nanotechnology, endovascular treatment, and new penile implants

Alternative medicines:

More and more people are turning to non-mainstream approaches to health care, which are outside western practices. They include alternative contemporary medicines and Integrative therapies.

Alternative medicines include herbal products, nutraceutical products, dietary supplements, and probiotics available as tablets, powder, syrup, capsules, teas, and extracts. The global complementary and alternative medicine market size is valued at USD 82.27 billion in 2020 and is expected to expand at a compound annual growth rate (CAGR) of 22.03% from 2021 to 2028.

A recent study 11 reports that the FDA is developing a framework under which CBD-containing products could be labeled as dietary supplements, supported by expanded research, a corporate stewardship program, and a rigorous adverse event reporting system.

Does CBD help treat symptoms of erectile dysfunction?

Well, we might not always get direct answers to what we seek.

We are aware that research is inadequate in several areas of medical cannabis and its pharmacological aspects.

But, Hemppedia has compiled several blog posts about the various therapeutic aspects of cannabidiol CBD, the non-psychoactive compound of the cannabis sativa plant. Moreover, we have also discussed other cannabinoids (CBG, acidic forms, THCA, THC, CBDA) and their potential health benefits in managing mental, neurological, pain, and inflammatory conditions and a lot more.

So, let us try to connect some dots and explore the role of cannabinoids in improving the quality of life for men affected with ED.

In this blog post, we discussed the symptoms of endocrine, non-endocrine, psychogenic, and compounding factors that lead to erectile dysfunction.

The 2018 study 12 confirmed that endogenous cannabinoids have a role in regulating food intake and energy homeostasis of the body, and have a significant impact on the endocrine system, including the activity of the pituitary gland, adrenal cortex, thyroid gland, pancreas, and gonads. This establishes the interrelations between the endocannabinoid system (ECS) and the endocrine system and could be a potential target for proving the therapeutic benefits of several drugs in the treatment of infertility, obesity, diabetes, and prevention of cardiovascular diseases.

Let us once again recall the neurogenic causes of ED.

  • In the blog post, CBD for Multiple Sclerosis, we had pointed out the benefits of using CBD to treat symptoms of Multiple Sclerosis to improve the quality of life of most patients.

A study published in 2013 13 in the journal “Neurobiology of Disease” addresses this topic. It confirms cannabidiol (CBD) long-lasting protection against harmful effects of inflammation in a viral model of multiple sclerosis.

  • CBD blocks a receptor known as GPR6 that is known to cause some impaired movements in a patient with Parkinson’s. Another study showed positive results and improved the quality of life of affected patients without any other psychiatric disorder.
    blog post brings out references from studies that analyzed the use of cannabis and CBD for high-risk sports professionals. The role of CBD in decreased inflammatory cell activation, improvements in mood for traumatic brain injury, concussions, and pain management is noteworthy here.
  • CBD can stimulate the growth of the hippocampus, thereby triggering the creation of new neurons. Neurogenesis can be a powerful method to reduce the symptoms of anxiety disorders and depression. Moreover, cannabis and its components help alleviate depression and stabilize moods (induced by chronic stress) by activating paralimbic and limbic areas in the patient’s brain. CBD has a role in modulating serotonin levels and promoting restful sleep.
  • CBD for Enlarged Prostate (Benign Prostatic Hyperplasia): BPH is a condition of an enlarged prostate, not necessarily cancer. Symptoms like painful urination, pain in the hips and pelvic area, blood in the urine or semen, painful ejaculation, and frequent urination show up. Urinary tract infection (UTI), kidney stones, and increased testosterone production could also lead to BPH.

Let us quickly understand some terms here. Testosterone is the male sex hormone that regulates sex drive or libido, bone and muscle mass, fat, red blood cells, and sperm production. And, Leydig cells present in the seminiferous tubules in the testicle are responsible for producing testosterone, the male sex hormone.

Therefore, the role of CBD in inhibiting testosterone is noteworthy. A 1979 study 14 reported that cannabinoids at very low concentrations may interfere directly in Leydig cells with both protein and testosterone synthesis, and thus with their function.

  • Having discussed the role of CBD, a few points about THC are mention-worthy.

Two hormones are essential for reproduction ( both male and female): Luteinizing hormone (LH) and follicle-stimulating hormone (FSH). These get secreted from the pituitary gland called gonadotrophs.

A 1984 study 15 reports that THC lowers the LH and FSH, which are responsible for reduced testosterone production by the Leydig cells of the testis. Moreover, THC suppresses prolactin, thyroid gland function, and growth hormone while elevating adrenal cortical steroids.

In essence, we have understood that sex is more than a physical relationship. Homeostasis of the mind and body together play a crucial role in sexual health and vice versa.

How to use CBD oil for erectile dysfunction?

The exact manner in which CBD oil for erectile dysfunction works is not yet fully understood. Unlike THC, CBD is not psychoactive and does not make you high. But the calming and relaxing properties of CBD regulates mood, stress, and performance anxiety leading to the possibility of boosting libido.

There are only tertiary references about the use of cannabis-derived CBD products, including CBD oil, capsules, concentrates, CBD edibles, CBD lube, or lubricants for managing pain, discomforts in ED.

Since there are different formulations of CBD, the best and the easiest choice is CBD oil. CBD oil comes in different strengths and potencies. Most importantly, in the context of ED, since we have discussed the negative effects of THC in male hormone function, make sure to procure high-quality CBD products that are THC-free.

CBD and Erectile Dysfunction: Are There Benefits?

Yvelette Stines, MS, MEd, is an author, writer, and communications specialist specializing in health and wellness.

Verywell Health articles are reviewed by board-certified physicians and healthcare professionals. These medical reviewers confirm the content is thorough and accurate, reflecting the latest evidence-based research. Content is reviewed before publication and upon substantial updates. Learn more.

Jamin Brahmbhatt, MD, is a board-certified urologist and Chief of Surgery at Orlando Health South Lake Hospital.

Erectile dysfunction (ED) affects approximately 52% of people between the ages of 40 and 70 years of age who have a penis. It is estimated that there will be 322 million cases globally by the year 2025.

Cannabidiol (CBD) is a compound derived from the cannabis plant that has become increasingly popular as a natural treatment for a range of health conditions. Some research suggests that CBD has the potential to help manage pain, reduce anxiety, and improve mood.

While there’s currently no evidence that CBD can effectively treat ED, CBD has been shown to help with some of the underlying physical and psychological causes of ED.

This article will look at the possible benefits of CBD for ED, how to use the oil, and the potential risks and side effects.

PeopleImages / E+ / Getty Images Plus

What Is Erectile Dysfunction?

Erectile dysfunction is defined as the inability to achieve or maintain an erection more than 75% of the time. It can be frustrating, and it also can impair the quality of life for those who experience it.

This condition may be triggered by a number of factors, including hormonal changes, side effects from medication, reduced blood flow, stress, or psychological concerns.

In addition, certain health conditions such as diabetes, heart disease, high cholesterol, sleep disorders, alcoholism, obesity, and Parkinson’s disease have been shown to increase the risk of developing ED.

What Is Cannabidiol (CBD)?

Cannabidiol (CBD) is one of over 85 active chemical compounds found in the cannabis (marijuana) plant. Unlike the cannabis compound tetrahydrocannabinol (THC), CBD is not psychoactive, meaning it does not cause the feeling of getting “high.”

Researchers have found that CBD has anti-inflammatory, antioxidant, and neuroprotective properties. It shows promise as a treatment for mood, sleep, and pain disorders due to its effects on the endocannabinoid system.

The endocannabinoid system involves a body-wide network of cannabinoid receptors that help regulate a number of important functions, including digestion, immunity, inflammation, reproductive health, and pain. CBD can activate these receptors, which may have potential health benefits.

Benefits of CBD Oil for ED

There is currently no research on the benefits of using CBD to treat erectile dysfunction specifically. And one recent review suggested that CBD may impair male sexual function.

However, there is evidence that CBD may be beneficial in treating underlying health conditions that can cause ED. In particular, CBD has been shown to aid in reducing stress and anxiety in multiple studies. It also shows potential for managing depression, performance anxiety around public speaking, and social anxiety.

Stress, anxiety, and depression are all known to impair libido and increase the risk of ED. The effects of CBD may help improve libido in people who struggle with ED due to psychological reasons. More research needs to be done to determine the effectiveness of CBD and the best dosage.

CBD has also been shown to lower blood pressure. This has the potential to improve circulation, which may help facilitate more blood flow to the penis.

Are There Any Side Effects?

Overall, using CBD oil is considered generally safe. Some people may experience a reaction or side effects such as fatigue, change in weight and appetite, and diarrhea.

Studies have also shown that CBD can interfere with certain medications, so it is important to contact your healthcare provider before trying any alternative treatments like CBD for ED.

Best CBD for Erectile Dysfunction

There are different ways that you can use CBD oil for your ED.

Topical oils and CBD-infused lubricants can be applied to the penis and the medicine will go directly to the skin. This can help promote blood flow to the penis, which can aid in getting a firm erection. Be sure to read the ingredients of these products as some may include additives that could cause sensitivity or a reaction.

The other way to use CBD is to consume it. Consumable forms of CBD include:

  • Chewing gum
  • Vaporized
  • Creams
  • Gummies
  • Liquid oils

When choosing a CBD product, you’ll find there are three main types of CBD oil on the market. They include the following:

  • Isolate CBD: This contains just CBD.
  • Broad-spectrum CBD: This contains CBD and other cannabinoids but not THC.
  • Full-spectrum CBD: This contains CBD and all other cannabinoids, including 0.3% or less trace amounts of THC.

Studies have shown that other cannabinoids may help increase the bioavailability and the activity of CBD due to a mechanism known as the entourage effect. For this reason, most proponents recommend using a broad or full-spectrum CBD.


There currently is no clinically recommended dosage for CBD oil. The effects vary from person to person, and it may take some experimentation to find a dose that is effective for you. Before trying CBD for ED, contact your healthcare provider and ask for their advice.

How to Buy CBD

CBD has been legalized across the United States and it is increasingly widely available. Places where you can get CBD oil include:

  • Manufacturer websites and retail locations
  • Large e-commerce sites
  • Health and wellness shops
  • Marijuana dispensaries


CBD has garnered some interest as a potential natural treatment for ED. While there’s limited evidence that CBD can treat ED specifically, the compound has been shown to reduce stress and anxiety and improve blood flow, which may be beneficial for ED.

A Word From Verywell

Dealing with ED can be frustrating, embarrassing, and hard on your relationship. If you are struggling with the condition, it’s important to talk with your healthcare provider, as ED can be indicative of an underlying health issue.

Your healthcare provider can help you rule out any health issues and help you understand your treatment options. CBD is one alternative option that is safe and easily accessible, so it may be worth trying along with other treatments.

There are many paths to treating ED effectively, and finding what works best for you may take some trial and error. But there is a way forward to a healthy, thriving sex life.

Frequently Asked Questions

During sex, CBD oil or a CBD-infused lubricant can be used externally on the genitals as you would any lubricant. It is thought to stimulate blood flow, reduce stress, and increase pleasure. You can also take CBD oil orally before having sex to help reduce performance anxiety and improve blood flow.

Some research suggests that CBD oil may help to lower blood pressure and increase blood flow. In terms of ED, increasing blood flow may help support erections.

There are a number of lifestyle habits that you can try that may help ED. These include exercising regularly, trying stress-reducing activities like yoga and meditation, eating a healthy diet, and creating space to take care of yourself.