Epidiolex Vs CBD Oil


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FDA approved Epidiolex (cannabidiol) oral solution, the first drug comprised of an active ingredient derived from marijuana, to treat two rare and severe forms of epilepsy. Epidiolex is a CBD-based pharmaceutical prescribed to treat epilepsy. Is it the same as CBD oil? Apparently not. Let’s dive into the differences between Epidiolex and CBD oil. Epidiolex is an FDA-approved cannabidiol (CBD) based oral solution used for the treatment of seizures in those with Dravet and Lennox-Gastaut syndrome.

FDA Approves First Drug Comprised of an Active Ingredient Derived from Marijuana to Treat Rare, Severe Forms of Epilepsy

The U.S. Food and Drug Administration today approved Epidiolex (cannabidiol) [CBD] oral solution for the treatment of seizures associated with two rare and severe forms of epilepsy, Lennox-Gastaut syndrome and Dravet syndrome, in patients two years of age and older. This is the first FDA-approved drug that contains a purified drug substance derived from marijuana. It is also the first FDA approval of a drug for the treatment of patients with Dravet syndrome.

CBD is a chemical component of the Cannabis sativa plant, more commonly known as marijuana. However, CBD does not cause intoxication or euphoria (the “high”) that comes from tetrahydrocannabinol (THC).

It is THC (and not CBD) that is the primary psychoactive component of marijuana.

“This approval serves as a reminder that advancing sound development programs that properly evaluate active ingredients contained in marijuana can lead to important medical therapies. And, the FDA is committed to this kind of careful scientific research and drug development,” said FDA Commissioner Scott Gottlieb, M.D. “Controlled clinical trials testing the safety and efficacy of a drug, along with careful review through the FDA’s drug approval process, is the most appropriate way to bring marijuana-derived treatments to patients. Because of the adequate and well-controlled clinical studies that supported this approval, prescribers can have confidence in the drug’s uniform strength and consistent delivery that support appropriate dosing needed for treating patients with these complex and serious epilepsy syndromes. We’ll continue to support rigorous scientific research on the potential medical uses of marijuana-derived products and work with product developers who are interested in bringing patients safe and effective, high quality products. But, at the same time, we are prepared to take action when we see the illegal marketing of CBD-containing products with serious, unproven medical claims. Marketing unapproved products, with uncertain dosages and formulations can keep patients from accessing appropriate, recognized therapies to treat serious and even fatal diseases.”

Dravet syndrome is a rare genetic condition that appears during the first year of life with frequent fever-related seizures (febrile seizures). Later, other types of seizures typically arise, including myoclonic seizures (involuntary muscle spasms). Additionally, status epilepticus, a potentially life-threatening state of continuous seizure activity requiring emergency medical care, may occur. Children with Dravet syndrome typically experience poor development of language and motor skills, hyperactivity and difficulty relating to others.

Lennox-Gastaut syndrome begins in childhood. It is characterized by multiple types of seizures. People with Lennox-Gastaut syndrome begin having frequent seizures in early childhood, usually between ages 3 and 5. More than three-quarters of affected individuals have tonic seizures, which cause the muscles to contract uncontrollably. Almost all children with Lennox-Gastaut syndrome develop learning problems and intellectual disability. Many also have delayed development of motor skills such as sitting and crawling. Most people with Lennox-Gastaut syndrome require help with usual activities of daily living.

“The difficult-to-control seizures that patients with Dravet syndrome and Lennox-Gastaut syndrome experience have a profound impact on these patients’ quality of life,” said Billy Dunn, M.D., director of the Division of Neurology Products in the FDA’s Center for Drug Evaluation and Research. “In addition to another important treatment option for Lennox-Gastaut patients, this first-ever approval of a drug specifically for Dravet patients will provide a significant and needed improvement in the therapeutic approach to caring for people with this condition.”

Epidiolex’s effectiveness was studied in three randomized, double-blind, placebo-controlled clinical trials involving 516 patients with either Lennox-Gastaut syndrome or Dravet syndrome. Epidiolex, taken along with other medications, was shown to be effective in reducing the frequency of seizures when compared with placebo.

The most common side effects that occurred in Epidiolex-treated patients in the clinical trials were: sleepiness, sedation and lethargy; elevated liver enzymes; decreased appetite; diarrhea; rash; fatigue, malaise and weakness; insomnia, sleep disorder and poor quality sleep; and infections.

Epidiolex must be dispensed with a patient Medication Guide that describes important information about the drug’s uses and risks. As is true for all drugs that treat epilepsy, the most serious risks include thoughts about suicide, attempts to commit suicide, feelings of agitation, new or worsening depression, aggression and panic attacks. Epidiolex also caused liver injury, generally mild, but raising the possibility of rare, but more severe injury. More severe liver injury can cause nausea, vomiting, abdominal pain, fatigue, anorexia, jaundice and/or dark urine.

Under the Controlled Substances Act (CSA), CBD is currently a Schedule I substance because it is a chemical component of the cannabis plant. In support of this application, the company conducted nonclinical and clinical studies to assess the abuse potential of CBD.

The FDA prepares and transmits, through the U.S. Department of Health and Human Services, a medical and scientific analysis of substances subject to scheduling, like CBD, and provides recommendations to the Drug Enforcement Administration (DEA) regarding controls under the CSA. DEA is required to make a scheduling determination.

The FDA granted Priority Review designation for this application. Fast-Track designation was granted for Dravet syndrome. Orphan Drug designation was granted for both the Dravet syndrome and Lennox-Gastaut syndrome indications.

The FDA granted approval of Epidiolex to GW Research Ltd.

The FDA, an agency within the U.S. Department of Health and Human Services, protects the public health by assuring the safety, effectiveness, and security of human and veterinary drugs, vaccines and other biological products for human use, and medical devices. The agency also is responsible for the safety and security of our nation’s food supply, cosmetics, dietary supplements, products that give off electronic radiation, and for regulating tobacco products.

CBD Oil vs Epidiolex — Which Is Better for Epilepsy?

The approval of Epidiolex in June 2018 signified a turning point in the treatment and management of seizures. Since the FDA-approved drug has CBD as its major component, its inclusion into the medical space as a prescription drug convinced even CBD’s skeptics of its potential

However, are Epidiolex and CBD Oil the same?

Proponents assume that since both products contain Cannabidiol, they must have the same uses. However, ongoing research does not support this claim.

This article seeks to spell out the differences between Epidiolex and CBD Oil, their principal pharmacological effects, side effects, and how best to increase the former and subdue the latter.

About Epilepsy

Epilepsy is a chronic non-communicable disease of the nervous system that affects about 50 million people worldwide. The condition is marked by unprovoked seizures, during which an individual loses voluntary control of the entire body or just a part of the body.

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One seizure does not make an epileptic. According to the World Health Organisation, an individual must have had at least two seizures in his lifetime to be diagnosed with epilepsy. Epilepsy is a sensitive condition; the risk of premature death in epileptics is three times that of an average person. Statistics declare that 70% of epileptics can live seizure-free with proper management.

Common medications used to manage epilepsy include anti-epileptic drugs (AEDs) such as Clonazepam, Diazepam, Valproic acid, which usually present with side effects like lack of energy, drowsiness, tremors, headaches, and hair loss.

CBD is a potent anti-seizure medication that has found its use in some particular kinds of epilepsy; the drug-resistant Dravet Syndrome, Lennox-Gastaut Syndrome which plagues infants, and in Tuberculosis Sclerosis Complex. CBD products present with milder side effects than typical AEDs and are much more tolerable.

The only FDA-approved brand of CBD for managing seizures is Epidiolex. Nonetheless, other formulations containing organically-sourced CBD will have similar effects on seizures. The potency of CBD Oil against a seizure is dependent on its dose, form, and preparation.

What is CBD?

CBD stands for cannabidiol. It’s one of the cannabinoids found in the Cannabis Sativa plant. CBD is not psychoactive like tetrahydrocannabinol (THC), its sister component. This makes it more appealing when it comes to relieving pain and other symptoms without psychoactive side effects, and is suitable for children above the age of two.

Cannabidiol is one of the most active ingredients of medical cannabis, second only to THC. You can derive it directly from the marijuana flowers, or by using larger amounts of hemp plants. It can also be manufactured in a laboratory. Cannabidiol comes in different forms such as oils, vapes, creams, extracts, and capsules.

Research on human and animals have suggested some benefits of CBD such as:

  • Anti-seizure properties
  • Neuroprotective effects
  • Anti-acne and Anti-inflammatory
  • Anti-cancer
  • Fights anxiety disorders
  • Lowers cravings for tobacco and heroin
  • Lowers high blood pressure
  • Improves sleep

What is Epidiolex?

Epidiolex is an extract from cannabis that contains 99% CBD that has been purified and is prescribed for medical purposes.

Although it contains no THC, as of 2018, it was placed on the list of controlled drugs and classified as a Schedule V prescription drug. This means that the regulatory body suspected that the drug may be subject to misuse by individuals seeking the psychoactive effects of THC.

As of 2020, Epidiolex was taken off the controlled drugs list, and pharmacists were free to dispense without retaining the prescription. Epidiolex remains a prescription-only drug. However, this legislation makes it easier to refill when it runs out.

Ingredients of Epidiolex

The formula of Epidiolex includes the following ingredients:

  1. Cannabidiol: the exact mechanism through which cannabidiol halts seizures remain unknown to scientists. One proposed mechanism involves the activation of the CB1 receptors of the endocannabinoid system, which are concentrated in the brain, and sparsely distributed in the periphery.
  2. Sucralose: Sucralose is an artificial sweetener. It has almost no calories and is 600 times sweeter than real sugar. Sucralose is used in ice cream and yogurt.
  3. Sesame seed oil: Sesame oil is edible vegetable oil. It is derived from sesame seeds. Sesame oil contains omega-3 and omega-6 fatty acids. It provides the benefit of protecting skin from sunburn and managing inflammation.

What is CBD Oil?

CBD oil is a viscous extract with high concentrations of CBD. The extract is diluted in a carrier oil, such as MCT oil or hemp seed oil to improve its bioavailability and speed up absorption. People use it for daily supplementation as well as to treat or manage the aforementioned health conditions.

Ingredients of CBD Oil

These are the following main ingredients:

  1. Hemp: A hemp flower is an unprocessed bud from the hemp plant. Hemp has a higher concentration of cannabidiol and a lower level of tetrahydrocannabinol.
  2. MCT Oil: MCT oil is a supplement made from medium-chain triglycerides. It is easily oxidized and breaks down rapidly to release energy. The oil, which can be found in coconut and palm oil, is rich in antioxidants and anti-inflammatory effects by activating neutrophils and mitochondrial reprogramming.

Comparing CBD Oil and Epidiolex: Epilepsy Treatment

Epidiolex in the Treatment of Epilepsy

Epidiolex is the first FDA-approved drug that is a CBD-derived medication for the treatment of epilepsy.

The FDA approved Epidiolex for the treatment of two severe and rare forms of epilepsy in patients two years of age and older — Lennox-Gastraut syndrome and Dravet syndrome. Epidiolex is also approved to treat seizures associated with tuberous sclerosis complex.

The job of the FDA is to protect public health by ensuring the safety, effectiveness, and security of human and veterinary drugs, vaccines, and other biological products for human use and medical services. First of all, the manufacturers of a product conduct laboratory, animal, and clinical testing. Then, the FDA reviews the results of the testing and grants approval.

Three clinical trials involving 516 patients with Lennox-Gastaut syndrome and Dravet syndrome studied the effectiveness of Epidiolex. In one of these trials, Epidiolex was combined with other anti-seizure medications. Compared to a placebo, Epidiolex was more effective in the reduction of seizures.

CBD Oil in the Treatment of Epilepsy

CBD oil is a mixture of Cannabidiol with a carrier oil. CBD oils that contain other compounds such as supportive cannabinoids, terpenes, and traces of THC are labeled as full-spectrum by manufacturers. The presence of these supporting compounds boosts the effect of CBD, a mechanism called the entourage effect. This phenomenon doesn’t occur in the highly purified Epidiolex.

CBD oil may help in treating some seizure symptoms but it has some side effects. CBD Oil typically comes as a tincture, with a dosage of 25-50mg of CBD per ml. The CBD market isn’t regulated like the pharmaceutical industry, so there’s no standardization among products, both when it comes to potency and purity. Therefore, it’s difficult to evaluate the efficacy of specific dosages.

More research still needs to be carried out to understand the risks and benefits of CBD oil.

Which is Better in the Treatment of Epilepsy?

The option of Epidiolex and CBD Oil gives patients and caretakers a chance to individualize their regimen. The best pick would depend on each patient’s individual circumstances.

CBD oil has a broader spectrum of activity and fewer side effects. It may treat other coexisting conditions such as acne and inflammation, as opposed to the rash occasionally associated with Epidiolex use. Even so, always consider the effect of seizure relief. At the appropriate dosage, CBD Oil is just as potent as Epidiolex.

What to Consider When Choosing Between Epidiolex vs CBD Oil


The FDA is yet to approve any commercial CBD brands for the treatment of epilepsy. Epidiolex is a prescribed drug that has gone through well-controlled clinical trials, has been reviewed and approved by the Food and Drug Administration (FDA) to treat Lennox-Gastraut and Davet syndrome. You may get a prescription for Epidiolex, and purchase it at the nearest pharmacy.

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CBD oils are recommended by doctors and can be purchased from online or physical stores. You don’t need a prescription for such products.


FDA studies suggest Epidiolex has been proven to be safe. Epidiolex is a cannabis extract made up of 99% CBD that has been purified. It also contains no tetrahydrocannabinol. THC is a principal psychoactive component of cannabis with a “high” effect.

CBD oil may contain other cannabinoid compounds and some contaminants. The FDA does not regulate CBD products, so CBD oils are not proven to be safe. The concentration of THC may vary with the brand.


According to Dr. Devinsky, a professor of neurology, neurosurgery, and psychiatry at the NYU Grossman school of medicine and director of NYU Langone’s Comprehensive Epilepsy Center, “The approval of Epidiolex or cannabidiol is a landmark in medicine. It is the first time such a medication, based on a cannabis plant, has been approved and scientifically established to be an effective treatment in the United States.” The pharmacological actions of CBD are not fully understood. However, Dr. Devinsky says, “We do understand some of how it helps to control seizures (by working) on a receptor system that no other drug touches.”

More research still needs to be carried out to understand the effectiveness of CBD oil.

Side Effects

Clinical trials carried out on Epidiolex suggest significant side effects were experienced by some of the participants like fever, vomiting, diarrhea, lethargy, fatigue, and drowsiness. Epidiolex may also lead to a change in liver function, jaundice, unusual darkening of the urine, and right upper abdominal pain.

CBD, the main component of CBD oil, is well-tolerated and its effects are considered mild Some of these adverse reactions include abnormalities in liver function, drowsiness, diarrhea, and dry mouth. In some studies, some patients experienced an increase in seizures with CBD. CBD Oil may interact with other medications, such as blood thinners.


It can be expensive to purchase Epidiolex. However, insurance may cover it in certain regions. The Epidiolex Copay Savings Program is eligible to legal residents of the United States or Puerto Rico. Some people who lack access to these privileges opt to buy CBD products from stores as an OTC alternative.

How to Use Epidiolex vs CBD oil

How to Use Epidiolex

Epidiolex is a liquid pharmacological drug. It is administered orally. The required dosage of Epidiolex depends on body weight and symptom severity.

The dosage based on a child’s body weight:

  1. Starting dosage: 2.5 milligrams per kilogram (mg/kg) taken twice daily per oral.
  2. Maintenance dosage: 5 mg/kg taken twice daily per oral.
  3. Maximum dosage: 10 mg/kg taken twice daily per oral.

How to use CBD oil

Most CBD oils come in bottles with a dropper. There are no guidelines for the proper administration but there are methods of using CBD oil. CBD oil is administered sublingually. place a few drops under the tongue and retain for 30 to 60 seconds without swallowing. The dose may be 5mg-25mg daily depending on what you are treating.

Interactions Between CBD and Medications

Certain side effects may occur when CBD is used with other drugs and medications such as:

  • Antipsychotics
  • Benzodiazepines
  • Clonazepam
  • Fluoxetine
  • Erythromycin
  • Clarithromycin
  • Calcium channel blockers
  • Carbamazepine
  • Ketoconazole
  • Fentanyl
  • Rifampin

CBD inhibits some enzymes of the large family of CYP450 and alters the way they metabolize certain drugs. It’s a similar mechanism to the one demonstrated by grapefruit juice. When taken together with other medications, CBD may either decrease or increase its concentration in the bloodstream — leading to toxicity or subtherapeutic effects depending on the type of interaction.

If you take any medications, talk to your doctor before adding CBD oil to your routine. Doing so will help you find the right timing for both compounds, as well as the dose to avoid interactions.

Key Takeaways on CBD vs Epidiolex

The major difference between the purified and FDA-approved Epidiolex and CBD Oil brands is that Epidiolex contains 99% CBD and no other cannabinoids. CBD oils, on the other hand, contain supportive cannabinoids that enhance their pharmacological activity. On the flip side, CBD Oils may contain contaminants and psychoactive compounds if they’re improperly manufactured and not tested by a third-party laboratory.

CBD oils also vary in terms of potency, appearance, and taste, based on brand. This may be desirable when a wider range of options positively affects treatment results.

People now have the choice of using Epidiolex or CBD oil to treat epilepsy. You need to know what they are and how they work before choosing your treatment option. If you would like to explore the prescribed medication, Epidiolex, or store-bought CBD oil, talk to your doctor first.


  1. Esposito, L. (2020), CBD Oil for Treating Epilepsy, U.S News and World Report L.P.
  2. FDA, (2018), FDA Approves First Drug Comprised of an Active Ingredient Derived from Marijuana to Treat Rare, Severe Forms of Epilepsy, FDA News Release.
  3. Iffland, K., Grotenhermen, F. (2017), An Update on Safety and Side effects of Cannabidiol: a Review of Clinical Data and Relevant Animal Studies, Mary Ann Liebert, Inc. 2(1), 139-154.
  4. World Health Organization (2022). Epilepsy. WHO.int. Retrieved from: [1]
  5. Abu-Sawwa, R., & Stehling, C. (2020). Epidiolex (Cannabidiol) Primer: Frequently Asked Questions for Patients and Caregivers. The journal of pediatric pharmacology and therapeutics: JPPT: the official journal of PPAG, 25(1), 75–77. [2]
  6. Martinez, M. (2021). CBD May Help People with Epilepsy Better Tolerate Anti-Epilepsy Medications. John’s Hopkins Medicine. Retrieved from: [3]
  7. Yu, Go, & Kim. (2019). Medium Chain Triglyceride (MCT) Oil Affects the Immunophenotype via Reprogramming of Mitochondrial Respiration in Murine Macrophages. Foods, 8(11), 553. [4]
  8. Singh, J., & Antimisiaris, M. F. (2020). Epidiolex-induced skin rash. Epileptic disorders: international epilepsy journal with videotape, 22(4), 511–514. https://doi.org/10.1684/epd.2020.1189
Livvy Ashton

Livvy is a registered nurse (RN) and board-certified nurse midwife (CNM) in the state of New Jersey. After giving birth to her newborn daughter, Livvy stepped down from her full-time position at the Children’s Hospital of New Jersey. This gave her the opportunity to spend more time writing articles on all topics related to pregnancy and prenatal care.

What Is Epidiolex?

Epidiolex is an oral solution containing cannabidiol (CBD). It is available on prescription in the US to treat seizures in Dravet syndrome, Lennox-Gastaut syndrome (LGS), or tuberous sclerosis complex (TSC) in those ages one and older. A systematic review including human clinical trials concludes that using oral CBD is associated with reducing seizure frequency in those with Dravet or LGS.

What Is Epidiolex?

Epidiolex is a pharmaceutical-grade CBD oral solution. It is a clear, colorless-to-yellow liquid containing CBD at a concentration of 100 milligrams per milliliter (100 mg/mL). Other ingredients include dehydrated alcohol, sesame seed oil, strawberry flavor, and sucralose.

Epidiolex is the first FDA-approved cannabis-based medication in the US, initially for treating seizures in treatment-resistant forms of Dravet syndrome and LGS. Phase 3 clinical trials were initiated in 2015, and the FDA approved Epidiolex in June 2018. The trials showed a positive result in reducing seizures in children with Dravet syndrome and LGS.

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Epidiolex is approved for those with treatment-resistant seizures associated with Dravet, LGS, or tuberous sclerosis complex, but physicians may prescribe it off-label for other conditions.

Epidiolex is made with CBD derived from cannabis instead of being a synthetic cannabinoid. Epidiolex is a 99% pure oral CBD extract and does not contain tetrahydrocannabinol (THC), other cannabinoids, or terpenes.

Epidiolex vs. CBD Oil

Patients have a common question: “Are CBD oil and Epidiolex the same thing?” The answer is “No.”

When people talk about CBD oil, they usually refer to hemp-derived CBD oil that is legally available on the market. However, this is not approved for use for any particular medical condition by the FDA. CBD oils can be CBD-only (CBD isolates), broad-spectrum (CBD and terpenes, with no THC), or full-spectrum (CBD, terpenes, and up to 0.3% THC). Their quality is variable, and how accurate their labels are regarding cannabinoid content is up for debate (i.e., there is no standardization of hemp products).

Although 0.3% THC may not seem like much in theory, it may end up being up to 3 mg of THC per 1000 mg (gram) of product. Again, not necessarily a lot for many, but it can affect some who might be particularly sensitive to THC or need specific, extremely low doses. If large doses are required for any effect in a non-pharmaceutical product (e.g., three 30 ml bottles per day), this can end up being a larger amount of THC being ingested. This can cause great variability in a product’s effects. The fact that so many products are inaccurate in their THC and CBD measurements complicates matters further.

Indeed, one study shows that people who used artisanal CBD had a 70% increase in seizures, whereas people utilizing pharmaceutical-grade CBD showed a reduction in seizures. Although the study’s sample size was small (only 31 people), it is worth bearing in mind that the variability of non-regulated, hemp-derived CBD products and the cannabinoids and terpenes in them play a part in determining what effect they have when ingested.

Uses and Health Benefits

CBD has displayed anti-inflammatory properties on top of its well-established anti-seizure properties, making it helpful in treating many different health problems. But we cannot say whether or not CBD is beneficial for health beyond those established by scientific research.

Adverse Side Effects

Adverse side-effects of Epidiolex can include, but are not limited to:

  • Sedation and sleepiness
  • Fatigue
  • Sleep problems
  • Rash
  • Decreased appetite
  • Nausea and vomiting
  • Diarrhea
  • Fever
  • Infections
  • An increase in liver enzymes
  • Negative interactions with other anti-seizure medications

Potential Interactions

CBD may interact with the following antiepileptic drugs (AEDs):

  • Clobazam
  • Stiripentol
  • Valproic acid and sodium valproate
  • Topiramate
  • Eslicarbazepine
  • Zonisamide
  • Brivaracetam
  • Gabapentin
  • Pregabalin

CBD and medical cannabis may also interact with sedatives and antihistamines with sedative properties like zolpidem (Ambien), eszopiclone (Lunesta), and diphenhydramine (Benadryl). Anti-anxiety medications and antidepressants as well, like alprazolam (Xanax), diazepam (Valium), chlordiazepoxide (Librium), sertraline (Zoloft), fluoxetine (Prozac), and escitalopram (Lexapro). CBD may also interact with blood thinners like warfarin.

Frequently Asked Questions

Is Epidiolex the same as CBD oil?

No, they are not. Epidiolex is FDA-approved and is a pharmaceutical product produced by Greenwich, a subsidiary of GW Pharmaceuticals. CBD oil is not a pharmaceutical product and is not available for prescription, and is not approved for any medical use by the FDA. Although Epidiolex uses cannabis plants for its CBD, the product is made to a different standard compared to hemp-derived CBD oils.

Is Epidiolex a narcotic?

The DEA has descheduled Epidiolex and is not legally considered a “narcotic.” CBD does, however, have psychoactive effects, even if they’re not necessarily intoxicating or psychotropic in the same way THC is. CBD and THC are different compounds and affect the endocannabinoid system (ECS) differently.

In 2019, the Legislature formally rescheduled Epidiolex as a Schedule V controlled substance. On April 6, 2020, the DEA descheduled Epidiolex entirely, meaning it is no longer subject to the Controlled Substances Act (CSA) and its tracking and monitoring requirements. You are legally permitted to cross state lines in the US with Epidiolex in your possession.

Do you need a prescription to get Epidiolex?

Yes, you will need a prescription to purchase Epidiolex, and you will need to find a specialty pharmacy, too. More information can be found here.

Is it possible to test positive for marijuana when using Epidiolex?

There is the possibility of testing positive for marijuana metabolites on urine drug screenings due to Epidiolex use. However, technically this should be unlikely as most drug screenings do not test for CBD. Patients/caregivers should inform the drug testing site that they have a prescription for Epidiolex from their doctor.

Can I or my child get addicted to Epidiolex?

Current research suggests that CBD is not addictive.

Can I drive under the influence of Epidiolex?

Some people may feel sleepy after consuming Epidiolex (especially if combined with other AEDs, anti-anxiety medications, or alcohol), so it is not advisable to drive if such effects are felt. Many people develop a tolerance to the sedative effects of CBD after taking it for some time so that the sedative effects may subside over time.

Once you start understanding how Epidiolex affects you after ingestion, you can judge what you can do with it for yourself.

Article written by

Dipak Hemraj Head of Research and Education

Dipak Hemraj is a published author, grower, product maker, and Leafwell’s resident cannabis expert. From botany & horticulture to culture and economics, he wishes to help educate the public on why cannabis is medicine (or a “pharmacy in a plant”) and how it can be used to treat a plethora of health problems. Dipak wants to unlock the power of the plant, and see if there are specific cannabinoid-terpene-flavonoid profiles suitable for different conditions.

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