Top 10 Best CBD Oil for Pain in 2022—Reduce Chronic Pain & Inflammation
Managing any type of pain is a challenge. The complexities of choosing a medication that won’t interfere with performing routine tasks while still being strong enough to manage pain symptoms makes it easy to understand why so many seek an alternative to traditional pharmaceutical and OTC medications. One option whose popularity is growing exponentially is CBD oil. CBD oil is made from extracts of the cannabis or hemp plant and has shown a variety of benefits, including relief from acute and chronic pain.
CBD oil may be an effective pain reliever because of its influence on the body’s endocannabinoid system (ECS). CBD works with this system to regulate the central nervous, immune, and endocrine systems. Although CBD does not work directly on brain receptors, it influences them to help relieve pain. CBD may be the answer for those seeking pain management treatment using a naturally sourced cannabinoid that is free from adverse side effects and can be dosed to meet specific pain management needs.
Top Ten CBD Oils for Pain Relief
: Top Pick : Runner Up : Worthy Mention : Broad Product Variety : Many Offers : Various Options : High Bioavailability : Full Spectrum : Good Service : Full-Spectrum CBD Specialists
How Did We Select These 10 CBD Oils?
Finding the best CBD oil for pain options started with a wide variety of CBD oil products. Our team of testers used a scoring system that took into account the CBD potency, price, taste, and customer service. The ten best CBD oils for pain on this list have high-quality ingredients, third-party lab testing, and competitive prices. They also offer a wide range of potencies so that you can find the perfect CBD oil for your individual needs.
Whether you are a first-time user of CBD or an experienced CBD enthusiast, this list has the perfect choice for meeting your specific acute or chronic pain management needs.
Top 10 CBD Oils for Pain
CBDfx: Top Pick
- Multi-cannabinoid formula
- cGMP certified manufacturing facilities
- On-staff medical advisory board
- 60-day money-back guarantee
- Up to 25% discount on orders
- Only available to USA customers
CBDfx Company Info
Established in 2014, CBDfx is a key player in the CBD industry. They have been praised for their high-quality products and commitment to customer service. The company is based in California and offers a mix of capsules, gummies, vape oils, topicals, and tinctures for humans and pets.
Using a solvent-free supercritical CO2 extraction process to extract essential cannabinoids such as CBD, CBN, CBG, and Delta-9 from organically grown hemp plants, CBDfx utilizes GMP (Good Manufacturing Practice) certified facilities to ensure quality, consistency, and safety. Their third-party lab-tested products offer a safe and accurate way to manage your chronic or occasional pain without prescription drugs. They also provide a 60-day money-back guarantee so that you can try their products risk-free.
CBDfx CBD Oils
CBDfx has an extensive product line of CBD oil for pain management and to treat various conditions. Their 2:1 Wellness tincture combines the anti-inflammatory properties of CBD and CBG in formulas containing 500mg, 1000mg, 2000mg, 4000mg, and 6000mg of CBD, and 250mg of CBG.
These types of cannabinoid compounds provide an entourage effect that is effective for pain management. CBDfx also offers their potent full-spectrum CBD oil for pain formulas with added natural ingredients to promote calm, better sleep, and appetite.
Who Should Use CBDfx Products?
CBDfx products are ideal for those experiencing chronic pain and inflammation, as well as those seeking relief from acute injuries. For those looking for an all-in-one health and wellness supplement to manage chronic pain in addition to other chronic conditions such as anxiety, insomnia, or depression, CBDfx provides the best CBD oils with multiple cannabinoids and added botanical extracts.
CBDistillery: Runner Up
- Formulas available in broad and full spectrum
- Excellent online user interface
- Ability to shop by ailment/condition/benefit
- US Hemp Authority Certified
- The safety mechanism on the dropper can be difficult to use at first
CBDistillery Company Info
Focused on transparency, quality, and the pursuit of wellness for all individuals, CBDistillery is a leader in the CBD industry. Based out of Colorado, CBDistillery was one of the first companies to receive US Hemp Authority Certification. Their products are made from organically grown hemp and undergo third-party lab testing to ensure purity and potency. Their formulas are available in both broad-spectrum and full-spectrum CBD oil varieties so that you can find the perfect oil for your specific needs.
CBDistillery CBD Oils
CBDistillery oils for pain relief come in 4 different potencies:
- Regular Strength – 500mg of CBD
- Extra Strength – 1000mg of CBD
- Maximum Strength – 2500mg of CBD
- Maximum Plus Strength – 5000mg of CBD
Full-spectrum CBD oil formulas use a CO2 extraction process to ensure that all beneficial cannabinoids and terpenes are included in the oil. In addition, the formula is blended with coconut carrier oil (MCT oil) to provide the synergistic benefits of fatty acids and better absorption into the body.
For those that don’t want to ingest the trace THC amounts found in CBDistillery’s full-spectrum CBD oil, the CBD company offers broad-spectrum CBD and CBD isolate formulas that are just as potent without any trace of THC.
Who Should Use CBDistillery Products?
Anyone looking for a high-quality, budget-friendly broad-spectrum or full-spectrum CBD oil online should consider CBDistillery. Additionally, those who do not like CBD oil’s earthy taste will enjoy the natural fruity flavors incorporated into various CBD products offered online at CBDistillery.
Sunday Scaries: Worthy Mention
- Flavored CBD oil tincture
- Low dose perfect for beginners
- Enriched with anti-anxiety vitamins
- THC-free broad-spectrum formula
- Limited supply in comparison to other products available
Sunday Scaries Company Info
Created by those who understand the effects of stress on the body, Sunday Scaries is a CBD company focused on providing everyday CBD wellness tinctures. Certified with just about every popular CBD certification you can think of, Sunday Scaries is committed to providing safe products that incorporate broad-spectrum natural CBD oils.
Offering subscription-based and one-time purchases, the team at Sunday Scaries is committed to providing anxiety-free living as an effective solution to chronic and acute pain.
Sunday Scaries CBD Oils
The Sunday Scaries CBD tincture is a THC-free, broad-spectrum CBD oil enriched with essential vitamins B12 & D3 and a coconut carrier oil for the best in absorption and bioavailability. Low in dose (500mg of CBD per bottle), this is a great introductory oil for those who have never used CBD before to start their journey to a stress and pain-free life. Enhanced with a light fruit punch flavor, Sunday Scaries oil tastes great on its own or mixed with water or tea.
For those looking for a best CBD oil for pain relief in addition to a powerful sleep aid, Sunday Scaries also offers a sleep formula that includes a variety of additional cannabinoid compounds to ensure a restful night’s sleep as well as providing powerful anti-inflammatory effects.
Who Should Use Sunday Scaries Products?
Sunday Scaries CBD products are perfect for those just starting their CBD journey, especially those looking for a THC-free option enhanced with essential vitamins.
Green Roads: Broad Product Variety
- Formulated by pharmacists
- Wide range of CBD products
- Rewards program
- Military, first responder, and teacher discounts
- Daily dose packets available
- A bit more expensive than other CBD brands on this list
Green Roads Company Info
Started by a pharmacist with 25 years of experience helping others, Green Roads is a popular provider of CBD oil online that strives to provide easy-to-take CBD products. With a variety of oils, edibles, spa products, soft gel capsules, and more available through their online store, Green Roads offers a way to manage pain and anxiety symptoms for everyone.
Green Roads CBD Oils
Unlike companies that stick to a few ingredients in their CBD oil tinctures, Green Roads goes above and beyond, formulating their proprietary blend of full and broad-spectrum CBD with no less than six active ingredients to manage pain and treat various ailments. The full and broad-spectrum CBD formulas are available in 30ml bottles containing 250-1500mg of CBD, depending on your potency preference. Additionally, these formulas are available in convenient daily dose packages for those who do not like to fuss with droppers or measuring. As an added benefit, Green Roads offers all of their CBD oil tinctures in a Kiwi Apple Bliss or Mint Breeze flavor in addition to the standard natural CBD flavor.
To further enhance a user’s CBD experience, Green Roads infuses their oils with various carrier oils, including hemp seed oil and sunflower oil, to provide essential fatty acids that are beneficial to the body.
Who Should Use Green Roads Products?
Green Roads CBD products are perfect for those who want high-quality, vegan, and gluten-free CBD oil available in various flavors and dosages.
Charlotte’s Web: Many Offers
- Available in large 100ml bottles
- Significant savings for subscription purchases
- Informative educational resources
- Ships to Canada
- Broad-spectrum formula only available in mint chocolate flavor
Charlotte’s Web Company Info
Boosted to international acclaim after being featured in some of the most reputable media outlets such as USA Today, The New York Times, and CNN, Charlotte’s Web is a world-renowned CBD company that was one of the first to market CBD products. B Corp Certified and family-owned, Charlotte’s Web offers many CBD products, including oils, capsules, topicals, and pet products designed to improve health and well-being.
Charlotte’s Web CBD Oils
Charlotte’s Web offers full-spectrum and broad-spectrum CBD oil formulas to help manage joint pain and other aches and pains that often accompany serious workouts. The full-spectrum CBD oil formulas have the most variety in potency, with 30ml bottles containing 7, 17, 50, and 60mg of CBD per mL. This means that there is a CBD oil for every need, whether you are a beginner or an experienced CBD user, or dealing with chronic pain or looking to relieve sore muscles or joint pain after working out. The broad-spectrum formula is THC-free and comes in a 25mg of CBD per mL bottle with a delicious mint chocolate flavor.
Using an alcohol extraction process to preserve the essential phytocannabinoid and terpene profiles, Charlotte’s Web oils are some of the purest and most effective on the market, especially for those suffering from acute inflammation and pain related to daily physical activity such as exercise.
Who Should Use Charlotte’s Web Products?
Charlotte’s Web CBD options are beneficial for those looking for a highly-effective, full-spectrum CBD formula that comes in large bottles to reduce cost per dose.
Zatural: Various Options
- Free shipping available
- Founded by a Naturopathic physician
- Voted Best Broad-Spectrum CBD 2021 by Miami Herald
- Potent CBD isolate formulas
- Full-spectrum formulas don’t ship to all 50 US states
Zatural Company Info
Founded by a woman who has dedicated her life to natural remedies and the science of alternative health, Zatural is a CBD company dedicated to helping people heal from chronic conditions related to pain, anxiety, and stress. Their products are made in the USA in an FDA-registered laboratory that adheres to Good Manufacturing Practices (GMP). Using the best in extraction methods, Zatural’s best CBD oil for pain options are potent and effective.
Zatural CBD Oils
Zatural offers CBD in full-spectrum, broad-spectrum, and CBD isolate formulas. The full-spectrum CBD oil formula is available in 30ml, 60ml, and 120ml bottles with CBD dosages as low as 300 mg and as high as 12,000mg of CBD per bottle. In addition, customers can choose between a natural CBD flavor or a peppermint flavor sweetened with stevia. The award-winning broad-spectrum formula is available in similar bottle sizes and CBD strengths with an additional array of flavors, including coffee, spearmint, lemon-lime, natural sweet, cinnamon, and peppermint.
For those looking for pure CBD that is THC-free, Zatural has you covered with a potent formula containing up to 2500mg of pure CBD. Their oils are formulated with hemp seed carrier oil for maximum CBD absorption and effectiveness.
Who Should Use Zatural Products?
Anyone experiencing chronic pain from arthritis, injuries, or other conditions, should try a Zatural CBD product. Their CBD oil has been shown to provide relief from chronic pain and inflammation using potent formulas containing high concentrations of CBD – particularly their isolate products.
CBD American Shaman: High Bioavailability
- Water-soluble CBD oils
- Nanotechnology enhances bioavailability
- Batch tested using Ultra Performance Convergence Chromatography
- Eco-friendly processing practices
- Other products offered on the website may not be gluten-free
CBD American Shaman Company Info
CBD American Shaman is a leader in the hemp-derived CBD industry, offering competitive pricing, proprietary CBD formulas, and the latest technology to make their best CBD oil products. CBD American Shaman uses non-GMO ingredients and eco-friendly processing practices to create pure, safe, and effective hemp oil extracts in full-spectrum and THC-free formulas.
CBD American Shaman CBD Oil
With various potencies, flavors, and bottle sizes, CBD American Shaman leaves nothing to be desired in their products. Their water-soluble CBD oils are some of the most bioavailable and effective oils on the market due to the nanotechnology-based enhancement of absorption.
Available in strengths ranging from 300 to 900 mg of CBD, these full-spectrum CBD oil options have everything a person needs to manage pain and other chronic conditions. Their terpene-rich formulas include considerable concentrations of Myrcene, Limonene, Linalool, A-pinene, and many others to benefit the body’s endocannabinoid system.
Who Should Use CBD American Shaman Products?
Anyone looking for high-quality CBD in a water-soluble oil to mix into their favorite drinks and meals as an alternative to sublingual drops should consider the high-quality oils formulated by CBD American Shaman.
Extract Labs: Full Spectrum
- ISO Certified labs
- International shipping available
- 100% secure checkout
- Excellent customer service
- Free shipping only on orders over $60
Extract Labs Company Info
One of the few American brands to offer international shipping, Extract Labs is committed to providing the highest quality CBD products to as many people as possible. Voted Top Ten CBD Oil in 2020, Extract Labs offers a full range of CBD products, from tinctures to capsules and topical ointments.
Founded by a military veteran who understands the need to provide the best CBD oil products, Extract Labs is one of the most reliable and customer-focused brands in the CBD industry.
Extract Labs CBD Oil
A customer favorite at Extract Labs is their 100% organic, vegan, and gluten-free CBD oil tincture. The high-quality CBD oil comes in a variety of strengths ranging from 300 mg to 3,000 mg so that customers can find the ideal dose for their pain management needs. The full-spectrum hemp extract oil contains quick-acting cannabinoids (CBG) that are ready to boost the body’s endocannabinoid system to provide relief from pain and other chronic conditions
For those seeking a THC-free alternative, Extract Labs offers a potent isolate formula that’s pure CBD – perfect for those who want to mix their daily dose of CBD into drinks and food.
Who Should Use Extract Labs Products?
CBD newbies and old-hands alike will appreciate Extract Labs’ high-quality tinctures that are potent and specifically designed to enhance the body’s endocannabinoid system.
Bloom Hemp: Good Service
- Independently owned and operated
- Certified organic
- Up to 20% discount available for new customers
- Manufactured in GMP and ISO certified facility
- No international shipping
- Domestic shipping more expensive than others on this list
Bloom Hemp Company Info
Started in 2018, Bloom Hemp has made it their mission to produce CBD products specifically designed to combat chronic and acute conditions such as pain, depression, digestive issues, and more using Ayurvedic practices combined with potent CBD formulas. Always going above and beyond the standards set within the CBD industry, Bloom Hemp products are certified organic with no pesticides, heavy metals, or solvents.
Bloom Hemp CBD Oil
For those seeking effective pain relief with CBD products that contain herbs and natural ingredients proven in Ayurvedic medicine to be powerful anti-inflammatories, Bloom Hemp’s oil might be a perfect choice. The Ayurvedic infusion in Bloom Hemp’s CBD oil helps to improve digestion, reduce inflammation, and promote a sense of calm and well-being with its proprietary Recovery Tincture that contains:
- 1200mg of CBD
- 100mg of CBG
- Terpene-rich profile: A-Pinene, Terpinolene, Linalool, Myrcene, B-Caryophyllene
- Turmeric extract
- Blackseed extract
- Ginger extract
Bloom Hemp also offers other full-spectrum CBD and THC-free formulas made with the same dedication to quality and purity as their oil.
Who Should Use Bloom Hemp Products?
Anyone looking for a high-quality, organic CBD oil that is Ayurvedically infused should consider Bloom Hemp. With discounts available for new customers, military personnel, and first responders, this brand is committed to making its premium CBD products affordable for all.
Five CBD: Full-Spectrum CBD Specialists
- Easy to navigate website
- Special deals and discounts
- Three flavors to choose from
- Multi-cannabinoid formula
- Online quiz to help select the best CBD product for customers
- No THC-free CBD oil is currently available
Five CBD Company Info
Focused on creating effective full-spectrum CBD oil tinctures that enhance the body’s endocannabinoid system, Five CBD is dedicated to providing relief to those suffering from chronic pain, anxiety, and other conditions. Offering an extensive online CBD knowledge base and a handy quiz to help customers select the perfect Five CBD products for their needs, this company uses its eco-friendly practices and organically grown hemp to create products that everyone can enjoy.
Five CBD Oil
Five CBD full-spectrum CBD oil tincture comes in natural, citrus, and lavender flavors. Customers can order potencies of 1500, 3000, and 6000mg of CBD per 30ml bottle. Containing a rich terpene profile and additional minor cannabinoids such as CBC and CBG, this oil is designed to maximize the body’s endocannabinoid system.
In addition to their potent tincture, Five CBD uses their full-spectrum CBD formula in a variety of other powerful products such as vape oils, gummies, chocolates, and soft gel capsules, all containing a 5:1 ratio of CBD to minor hemp compounds. Customers can choose to purchase one bottle at a time or save up to 20% on subscription purchases.
Who Should Use Five CBD Products?
Those looking for a high-quality full-spectrum CBD oil for pain that has been enriched with minor cannabinoids should try Five CBD. With discounts available for subscription purchases, Five CBD is the perfect company for those seeking affordable and reliable pain relief with all-natural products.
How to Choose the Best CBD Oil for Pain
When it comes to using powerful CBD supplements for their superior anti-inflammatory properties, there are many options to choose from. Considering that CBD oil tinctures and supplements come in various potencies and formulations, choosing the best CBD oils for pain relief comes down to understanding your needs and preferences. To make the CBD oil for pain choice that works best for you, it’s essential to consider a few key points.
- The severity of your pain
The more intense your pain, the more powerful the CBD you’ll need to find for an effective result. The CBD concentration per bottle doesn’t always determine power, however. Sometimes, the best way to manage acute or chronic pain is by choosing a CBD formula that contains essential terpenes, flavonoids, and phytocannabinoids found in the cannabis plant to provide what is known as the entourage effect.
The entourage effect causes the synergy between CBD and these other beneficial plant compounds extracted from the hemp plant to boost the body’s endocannabinoid system and relieve acute or chronic pain.
- Your general health and wellness
Depending on your overall health or current health and wellness goals, you might consider purchasing a CBD oil infused with additional vitamins and minerals to help supplement your diet. For example, a CBD oil tincture rich in omega-3 fatty acids and terpenes might be a better choice for those who are looking to improve their cardiovascular health in addition to providing pain relief.
- The frequency of dosing
If you experience chronic pain that requires daily doses of CBD oil for pain, you might want to consider an oil formulated with an effective carrier oil like hemp seed oil that improves absorption but has a low to medium CBD concentration. This allows you to take a single dose or up to a few doses per day.
On the other hand, if you only experience mild pain on an intermittent basis, you might be better served with an oil that comes in a smaller bottle with a more powerful CBD potency for pain relief as it happens.
- The type of CBD oil you’re considering
CBD oil tinctures come in three basic formulas: full-spectrum, broad-spectrum, and isolate. Full-spectrum CBD oil formulas are made using the whole hemp plant and contain all the cannabinoids, terpenes, and flavonoids naturally present in the hemp plant. This includes THC, but in very small trace amounts (
A broad-spectrum CBD product is similar to a full-spectrum CBD oil in that both contain all the cannabinoids and terpenes found in the hemp plant, but the broad-spectrum option has had the THC removed. This makes broad-spectrum oils an excellent way to get the benefits of CBD without the risk of putting THC in the body that you get from full-spectrum options.
CBD isolate is a pure form of CBD that has been isolated and concentrated into a potent therapeutic supplement for faster results. Isolate products contain no THC, other cannabinoids or terpenes and are the perfect choice for those who want to strictly take CBD without any other cannabinoids, terpenes, or flavonoids. Isolates are often preferred by those that want to mix their CBD with their favorite foods and beverages.
Each type of CBD has its own unique benefits for the user, and choosing the right one will depend on your needs, your body’s reaction to specific cannabinoid compounds and your preferred method of ingestion.
The Benefits of CBD Oil for Pain Relief
Studies are still ongoing regarding the benefits of CBD oil , and it’s an area that is growing all the time. The following conditions have been linked to positive results when users take CBD oil for pain relief.
- Depression & anxiety
- Heart disease
- Crohn’s disease
- Multiple sclerosis
The list is expanding as researchers are still finding new ways CBD can help with pain relief. But, so far, it seems that CBD is a safe and effective means of managing a wide variety of chronic and acute pain conditions with few to no side effects.
Currently, the FDA has only approved one CBD drug for use in the United States , but more drugs are in development at medical facilities across the country. As the CBD movement progresses and more research is done on the benefits of CBD, it seems likely that more ailments will be added to the list of illnesses managed with CBD oil in the future.
How to Use CBD Oil for Pain
Each CBD company has different dosing and usage directions for their products. Depending on the CBD oil you take, the method in which it is used, and your specific condition, there are a number of methods to choose from for using CBD oil.
CBD tinctures are the most popular form of CBD oil products and are administered by dropping a few drops under your tongue using the pipette applicator included in the bottle. Holding the oil under the tongue for a minute or two will help it absorb into the bloodstream faster than if you swallow it. You can also add CBD oil to food or drinks, but keep in mind that the bioavailability – the amount of CBD that actually gets absorbed into your system for pain relief – may be reduced when you add it to other substances. If you do choose to mix CBD oil into other substances, be sure to choose a water-soluble CBD oil or a CBD isolate with high bioavailability.
When you first begin using CBD oil for pain relief, it is important to start low and go slow. This means starting with a small dose and increasing gradually until you find the dosage that works best for you. Doing so will allow users to understand how their body reacts to CBD oil and will help to avoid any unpleasant side effects.
What Are the Side Effects of CBD Oil?
While CBD oil is a natural substance typically extracted from organically grown hemp plants that are free from harmful pesticides, heavy metals, and herbicides, there are still a few potential CBD oil side effects to be aware of. These side effects usually occur in new users who are not yet accustomed to the effects of CBD. Side effects may also occur in those that take too high of a dose, which is why starting low and slow is the best way to avoid them.
Side effects reported by new users or those that have taken too high of a dose include:
- changes in appetite
- changes in mood
- dry mouth
- nausea & vomiting
- upset stomach
- fatigue or drowsiness
These CBD oil side effects are very common and often subside after a few days of continued use, but if you do notice any unusual changes in mood or behavior, stop taking CBD oil and consult your healthcare provider immediately.
Frequently Asked Questions
1. How is CBD extracted from hemp?
There are a variety of extraction methods for creating CBD oil. They include ethanol extraction, olive oil extraction, and steam distillation. Currently, the best method is considered to be the CO2 extraction method as it preserves the full profile of the hemp plant’s natural compounds without leaving any harsh resins or solvents behind.
2. Is CBD oil psychoactive?
No, CBD oil is not psychoactive. CBD oil will not get you high and will not change your mental state in any way. If you are worried about trace amounts of THC in CBD oil products, consider purchasing broad-spectrum formulas or CBD isolates as they are THC-free.
3. How long does it take for CBD oil to work?
Effects vary between individuals. Many users report feeling CBD oil’s anti-inflammatory or calming effects within 30-90 minutes of dropping CBD oil under their tongue.
Get Effective Pain Relief With CBD Oil
CBD oil provides users with a natural alternative for pain relief without the potential side effects of OTC or pharmaceutical medications. All our options for the best CBD oils are focused on creating safe, effective, and affordable CBD oil products. Try one of the CBD oil for pain choices we’ve highlighted and take advantage of this helpful plant extract without worrying about the potential for adverse side effects.
This article is sponsored content. The editorial staff of 5280 had no role in the preparation of this content.
Complementary treatments and arthritis – from turmeric to cannabis oil
People use complementary medicine for many different reasons, including:
- wanting to use more natural treatments
- their symptoms aren’t fully controlled by conventional medicine.
Read more about complementary therapies which can help to ease the symptoms of arthritis, from yoga to meditation.
Are they right for me?
As with all complementary treatments, different things work for different people and it isn’t possible to predict which might be the most useful or effective.
There are some key points to consider if you’re thinking about using any complementary treatments.
- What are you hoping to achieve? Pain relief? More energy? Better sleep? Reduction in medication?
- What are the financial costs?
- Is there any evidence for their effectiveness?
Are complementary medicines safe?
Complementary medicines are relatively safe, although you should always talk to your doctor before you start any new treatment.
In specific cases they may not be recommended, for example, if you are pregnant or breastfeeding, or they may interact with certain medication.
A starter for five
Here we share a spotlight on the most popular complementary medicines that people call our helpline about.
It’s thought that turmeric can possibly reduce inflammation, which could help people with arthritis.
People with knee osteoarthritis who took part in a research trial reported improvements to their pain levels after taking turmeric. The evidence is limited however, as it is from just one trial. What evidence there is suggested that people only had minor side-effects after taking turmeric.
Turmeric can be bought from health food shops, pharmacies and supermarkets in the form of powder.
Glucosamine sulphate and glucosamine hydrochloride are nutritional supplements. Animal studies have found that glucosamine can both delay the breakdown of and repair damaged cartilage.
The results for the use of glucosamine for osteoarthritis are mixed and the size of the effect is modest. There’s some evidence that more recent trials and those using higher-quality methods are less likely to show a benefit.
Capsaicin is taken from chilli peppers. It works mainly by reducing Substance P, a pain transmitter in your nerves. Results from randomised controlled trials assessing its role in treating osteoarthritis suggest that it can be effective in reducing pain and tenderness in affected joints, and it has no major safety problems. Evidence for its effectiveness for fibromyalgia is related to a single trial.
Other names: Axsain®, Zacin®, chilli, pepper gel, cayenne
Capsaicin is licensed in the UK for osteoarthritis and you can get it on prescription in the form of gels, creams and plasters.
There are no major safety concerns in applying capsaicin gel/cream. A review of capsaicin applied to the skin to treat chronic pain (not specifically related to osteoarthritis, rheumatoid arthritis or fibromyalgia) concluded that around one third of people experience a reaction around the area where the treatment is applied. It’s important to keep capsaicin away from your eyes, mouth and open wounds because it will cause irritation. There have been no reported drug interactions.
Fish oils are rich in omega-3 essential fatty acids, which have strong anti-inflammatory properties. Fish liver oil is also a rich source of vitamin A (a strong antioxidant) and vitamin D (which is important for maintaining healthy joints).
Evidence suggests that fish body oil can improve the symptoms of rheumatoid arthritis. Unconfirmed evidence also suggests a combination of fish body and liver oils might also be useful in the long term, particularly in reducing the use of non-steroidal anti-inflammatory drugs (NSAIDs). There isn’t enough evidence for the use of fish liver oil for osteoarthritis.
Omega-3 fatty acids also play a role in lowering cholesterol and triglyceride levels in your blood, so they can reduce the risk of heart disease and stroke in people with inflammatory arthritis.
In the UK, dietary guidelines recommend eating two portions of fish a week, including one oily. Fish oil is considered to be well tolerated at this dose.
At the correct doses, side-effects are usually minor and uncommon.
Cannabis oil (CBD)
CBD is type of cannabinoid – a natural substance extracted from the cannabis plant and often mixed with an oil (such as coconut or hemp) to create CBD oil. It does not contain the psychoactive compound called tetrahydrocannabidiol (THC) which is associated with the feeling of being ‘high’.
Research in cannabinoids over the years suggests that they can be effective in treating certain types of chronic pain such as pain from nerve injury, but there is currently not enough evidence to support using cannabinoids in reducing musculoskeletal pain. We welcome further research to better understand its impact and are intently following developments internationally.
CBD oil can be legally bought as a food supplement in the UK from heath food shops and some pharmacies. However, CBD products are not licensed as a medicine for use in arthritis by MHRA (Medicines and Healthcare products Regulatory Authority) or approved by NICE (National Institute for Health and Care Excellence) or the SMC (Scottish Medicines consortium).
We know anecdotally from some people with arthritis, that CBD has reduced their symptoms. If you’re considering using CBD to manage the pain of your arthritis, it’s important to remember it cannot replace your current medicines, and it may interact with them, so please do not stop/start taking anything without speaking to a healthcare professional.
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